Am J Transplant, Volume 22, Suppl 3 Archives - Page 159 of 190 - ATC Abstracts

2022 American Transplant Congress
CD38 Knockout Mice Demonstrate Decreased Neutrophil Infiltration Following Renal Ischemia Reperfusion Injury
I. Woelfel¹, A. Ruffing¹, I. El-Ayachi¹, K. Washburn², S. Black¹, A. Schenk¹
¹Ohio State University, Columbus, OH, ²The Ohio State University, Columbus, OH
*Purpose: Ischemia reperfusion injury (IRI) perpetuates inflammation and causes significant organ injury in solid organ transplantation. CD38 is a ectoenzyme widely expressed on lymphocytes with…
2022 American Transplant Congress
Defects in Kim-1 Do Not Result In Delayed Graft Function After Kidney Transplantation
R. S. Suri¹, J. Lee², M. Ban³, B. Shrum², O. Z. Ismail⁴, S. Leckie⁵, A. McIntyre³, Q. Xu⁶, S. H. Lee², S. de Chickera², R. A. Hegele², L. Gunaratnam²
¹Research Institute of the McGill University Health Center, Montreal, QC, Canada, ²Schulich School of Medicine and Dentistry, Western University, Lodnon, ON, Canada, ³Robarts Research Institute, Lodnon, ON, Canada, ⁴University of Alberta, Edmonton, AB, Canada, ⁵London Health Sciences Centre, Lodnon, ON, Canada, ⁶University of Pittsburg Medical Center, Pittsburg, PA
*Purpose: Tissue repair is critical to restore organ function after ischemia-reperfusion injury (IRI) during transplantation. During renal injury, upregulation of kidney injury molecule-1 (KIM-1) transforms…
2022 American Transplant Congress
Understanding the Response of Human Lung Microvascular Endothelial Cells During Lung Transplantation via an In Vitro Model of Ischemia Reperfusion Injury
L. Chacon Alberty¹, M. King¹, G. Loor², E. Curty¹, C. Hochman-Mendez¹
¹Regenerative Medicine Research, Texas Heart Institute, Houston, TX, ²Baylor College of Medicine - Lung Transplant, Houston
*Purpose: Lung Transplantation (LTx) is a therapeutic option for patients with end-stage lung disease. One of the major complications is primary graft dysfunction largely attributed…
2022 American Transplant Congress
Early versus Late Ureteral Stent Removal in Pediatric Kidney Transplant Recipients
A. McGrath¹, L. Maestretti¹, S. Samreth¹, K. Sheth², P. Grimm², A. Chaudhuri², A. Gallo²
¹Stanford Children's, Palo Alto, CA, ²Stanford University, Palo Alto, CA
*Purpose: Routine placement of ureteral stent in pediatric kidney transplantation prevents complications by reducing vesicoureteral junction kinking, and promoting drainage from the transplant kidney to…
2022 American Transplant Congress
Case Times For Brain Dead Donors: Longer Is Not Better, No Impact Of Longer Case Time On Organ Yield Or OPO Performance Tier
M. J. Moritz¹, R. Hasz¹, H. Nathan¹, E. Hunt², S. Noreen³, A. Toll⁴
¹Gift of Life Donor Program, Philadelphia, PA, ²Surgery, Lehigh Valley Health Network, Allentown, PA, ³United Network for Organ Sharing, Richmond, VA, ⁴Research, United Network for Organ Sharing, Silverdale, WA
*Purpose: Having observed the steady increase in case times, we wished to examine if this has impacted organ yield*Methods: We conducted a retrospective cohort study…
2022 American Transplant Congress
Patient Preferences for Waiting Time and Kidney Quality: A Discrete Choice Experiment
S. Mehrotra
Industrial Engineering and Management Sciences, Northwestern University, Evanston, IL
*Purpose: The purpose of this study was to elicit patient preferences involving tradeoffs between a lower quality kidney offered today and a higher quality, future…
2022 American Transplant Congress
Less is More. Extensive Cardiac Investigations Add Little Value in Waitlisting Patients for Kidney Transplantation
B. Chow¹, M. Khurram², E. Capuano², F. Pugliese², M. Yaqoob², I. Mohamed²
¹Barts and the London School of Medicine and Dentistry, London, United Kingdom, ²Department of Renal and Transplantation, Royal London Hospital, Bart's Health NHS Trust, London, United Kingdom
*Purpose: Extensive cardiac investigations have long been considered necessary to aid decision-making in waitlisting for kidney transplantation. However, the utility and reliability of such comprehensive…
2022 American Transplant Congress
Humoral Response After a Third Dose of Sars-CoV-2 mRNA Vaccine in Transplant Recipients
A. E. Woolley, N. Sharma, G. Zhou, A. Kim, E. Ryan, M. Joyce, H. Goldberg, M. Givertz, M. Mehra, E. Woodcome, V. Durney, S. Marshall, K. Townsend, A. Coppolino, S. Tullius, S. Malek, H. Mallidi, L. Baden, A. Chandraker
Brigham & Women's Hospital, Boston, MA
*Purpose: Prior studies demonstrated an increased immune response post-3rd COVID-19 vaccine dose when given 1-month post-2nd dose in solid organ transplant recipients (SOT). This study…
2022 American Transplant Congress
Seroprevalence of HHV8 Among Donors and Recipients with HIV
P. H. Nambiar¹, T. Liang², J. D. Motter³, W. Werbel³, S. Mehta⁴, V. Kirchner⁵, M. Rana⁶, S. Florman⁷, J. Odim⁸, W. Miley⁹, N. Labo⁹, D. Whitby⁹, A. Massie¹⁰, D. Segev³, A. Tobian³, C. Durand²
¹Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, ²Medicine, Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD, ⁴New York University Langone Transplant Institute, New York, NY, ⁵University of Minnesota, Minneapolis, MN, ⁶Icahn School of Medicine at Mount Sinai, New York, NY, ⁷Mount Sinai Medical Center, New York, NY, ⁸National Institute of Health, Bethesda, MD, ⁹National Cancer Institute, Frederick, MD, ¹⁰Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Kaposi sarcoma (KS) can develop post-transplant via recipient HHV8 reactivation or donor-acquired HHV8. In the general US population, HHV8 seroprevalence is low (1-5%), yet…
2022 American Transplant Congress
Area Deprivation Index is Associated with Worse Patient Survival Following Adult Liver Transplantation
J. Hendele¹, J. Perkins², J. Nichols³, A. Dick¹
¹Division of Transplant Surgery, Department of Surgery, University of Washington, Seattle, WA, ²Clinical and Bio-Analytics Transplant Laboratory (CBATL), University of Washington, Division of Transplant Surgery, Department of Surgery, Seattle, WA, ³School of Medicine, University of Washington, Seattle, WA
*Purpose: Area Deprivation Index (ADI) has been utilized as a granular measure of local socioeconomic status for nearly two decades. This study is the first…