Am J Transplant, Volume 22, Suppl 3 Archives - Page 155 of 190 - ATC Abstracts

2022 American Transplant Congress
Impact of HLA Matching on Graft Survival in Kidney Transplant Recipients
J. Miller¹, N. Salkowski¹, B. Thompson¹, R. Kandaswamy², P. Stock³, A. Israni¹
¹Scientific Registry of Transplant Recipients, Minneapolis, MN, ²Department of Surgery, University of Minnesota Medical School, Minneapolis, MN, ³Department of Surgery, University of California San Francisco, San Francisco, CA
*Purpose: This study aims to estimate the association of HLA matching at the A, B, DR, and DQ loci with posttransplant graft failure and patient…
2022 American Transplant Congress
The Evolution of Hypogammaglobulinemia in Kidney Transplant Recipients and Its Associated Risk Factors
E. Jo¹, S. Min², A. Han³
¹Surgery, Seoul National University Hospital, Seoul, Korea, Republic of, ²Surgery, Seoul National University College of Medicine, Seoul, Kosovo, Republic of, ³Seoul National University College of Medicine, Seoul, Korea, Republic of
*Purpose: Hypogammaglobulinemia (HGG) has been extensively studied to identify a biological marker for infection. According to Florescu et al. (2013), a meta-analysis of 18 clinical…
2022 American Transplant Congress
The Role Of Combined Gene Expression Profiling And Donor-derived Cell-free Dna In Differentiating Acute Rejection In Liver Transplant Recipients
S. Park¹, M. Kandpal², K. Guo², S. Kleiboeker³, R. Sinha⁴, M. Abecassis⁵, J. Levitsky⁶
¹Transplant nephrology, Northwestern University, Chicago, IL, ²Northwestern University, Chicago, IL, ³Eurofins Viracor, Lee's Summit, MO, ⁴Eurofins Viracor, Lee's summit, MO, ⁵University of Arizona, Tucson, AZ, ⁶Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: In our previous studies, blood-based gene expression profiling (GEP) and donor-derived cell-free DNA (dd-cfDNA) have been independently validated in liver transplant recipients (LTR) to…
2022 American Transplant Congress
Tacrolimus After Rabbit Antithymocyte Globulin And Infliximab Induction Immunosuppression In Kidney Transplantation
O. Viklicky¹, G. Bold², O. Bestard³, P. Hruba¹, I. Zahradka¹, N. M. Otto², M. Stein², A. Sefrin², S. Christakoudi⁴, P. M. Reinke²
¹Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²Charité, Berlin, Germany, ³Vall d'Hebron, Barcelona, Spain, ⁴King's College, London, United Kingdom
*Purpose: Selective targeting of effector/memory T cells as induction immunosuppression has been discussed in kidney transplantation. Confidence-interval-estimation study may help to estimate range of the…
2022 American Transplant Congress
Higher Proinflammatory Cytokines Are Associated with Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients
A. H. Karaba¹, X. Zhu¹, S. E. Benner¹, O. Akinde¹, Y. Eby¹, K. H. Wang¹, S. Saraf², J. M. Garonzik-Wang³, S. L. Klein¹, J. R. Bailey¹, A. L. Cox¹, J. N. Blankson¹, C. M. Durand¹, D. L. Segev¹, W. A. Werbel¹, A. A. Tobian¹
¹Johns Hopkins University, Baltimore, MD, ²National Institute of Allergy and Infectious Diseases, Bethesda, MD, ³University of Wisconsin School of Medicine and Health, Madison, WI
*Purpose: Solid organ transplant recipients (SOTRs) are at increased risk for severe COVID-19 and exhibit lower antibody responses to SARS-CoV-2 vaccines. This study aimed to…
2022 American Transplant Congress
SARS-CoV-2 Infection is Associated with Greater Neutralizing Antibody Response Compared to Three Doses of Mrna-1273 Vaccine in Solid Organ Transplant Recipients
V. H. Ferreira, V. Hall, T. M. Marinelli, M. Ierullo, V. Kulasingam, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: Prior studies suggest that two doses of mRNA vaccine in SOTR may result in lower antibody and T-cell responses relative to levels seen following…
2022 American Transplant Congress
Additional Dose of SARS-CoV-2 Vaccine Increases Neutralization Capacity in Solid Organ Transplant Recipients
Y. Yoo¹, J. Husson², T. Iraguha³, S. Niederhaus⁴, X. Wen⁵, A. Crane⁵, A. Carrier⁵, J. Avruch⁵, A. Ahuja⁶, M. Mathew⁷, S. Dahiya⁸, A. P. Rapoport⁸, D. Atanackovic⁸, K. K. Saharia²
¹Inst of Human Virology, Baltimore, MD, ²Div of Infect Diseases, Univ of Maryland School of Med. and Inst of Human Virology, Baltimore, MD, ³Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD, ⁴Dept of Surgery, Univ of Maryland School of Med., Baltimore, MD, ⁵Dept of Surgery, Univ of Maryland Med. Center, Baltimore, MD, ⁶Dept of Medicine, Univ of Maryland Med. Center, Baltimore, MD, ⁷Div of Infect. Diseases, Univ of Maryland Med. Center, Baltimore, MD, ⁸Dept of Medicine, Univ of Maryland School of Med. and Greenebaum Comprehensive Cancer Center, Baltimore, MD
*Purpose: Solid organ transplant recipients (SOTR) develop weak antibody responses after SARS-CoV-2 vaccination. Published data on neutralizing activity of plasma, a better measure of protection,…
2022 American Transplant Congress
The Impact of Maintenance Immunosuppressive Regimen on COVID-19 Outcomes Among Kidney Transplant Patients
T. V. Sandes-Freitas¹, L. Modelli de Andrade², L. Requião-Moura³, J. Medina-Pestana³, H. Tedesco-Silva³, A. on behalf of Covid-19 KT Brazil Study Group¹
¹Universidade Federal do Ceará / Unidade Pesquisa Clínica CH-UFC/EBSERH, Fortaleza, Brazil, ²Universidade Estadual Paulista - UNESP, Botucatu, Brazil, ³Universidade Federal de São Paulo / Hospital do Rim, São Paulo, Brazil
*Purpose: Compared to azathioprine (AZA), mycophenolate (MPA) is implicated in an increased risk of several viral infections. Contrariwise, mTOR inhibitors (mTORi) are protective. Therefore, the…
2022 American Transplant Congress
What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?
G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo
Research, United Network for Organ Sharing, Richmond, VA
*Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…
2022 American Transplant Congress
Eliminating Hepatitis C Positive Status from Kidney Donor Profile Index (KDPI) Calculations Results in Improved Transplant Rates and Outcomes in an Elderly Veteran Population
R. Lopez-Soler¹, A. Thorndyke¹, C. Trotter¹, A. Abadier², M. Samra¹
¹Surgery, Transplantation, Edward Hines Jr. Veterans Administration Hospital, Hines, IL, ²Surgery, Loyola University Medical School, Maywood, IL
*Purpose: Overall mortality on the kidney transplant waiting list is higher for older patients. The average age of waitlisted veteran patients is 64, with patients…