Am J Transplant, Volume 22, Suppl 3 Archives - Page 151 of 190 - ATC Abstracts

2022 American Transplant Congress
A Population-Based Analysis of Long-Term Outcomes Following Pediatric Acute Liver Failure Highlights High Risk Populations in Access to Transplant
J. Ascher Bartlett¹, M. Lo², K. Etesami³, L. Sher³, R. Kohli¹, J. Emamaullee³
¹Gastroenterology, Hepatology and Nutrition, Children's Hospital Los Angeles, Los Angeles, CA, ²University of Southern California, Los Angeles, CA, ³Surgery, Keck Medicine of University of Southern California, Los Angeles, CA
*Purpose: Pediatric acute liver failure (PALF) is a potentially devastating illness that affects otherwise healthy children. Nearly 70% of children with PALF will recover, while…
2022 American Transplant Congress
Marginal Zone Phenotype B Cells Are Required for Formation of Donor-Specific IgG After Allogeneic Sensitization
M. A. Kallarakal, G. Cohen, S. M. Krummey
Department of Pathology, Johns Hopkins University, Baltimore, MD
*Purpose: The formation of allogeneic antibody directed against non-self MHC, termed donor-specific antibody (DSA), is a significant barrier to successful transplant outcomes. Pre-formed DSA limits…
2022 American Transplant Congress
Regulatory T Cells Suppress Memory IL-17a Production in Highly Sensitised Patients with End-Stage Renal Disease
C. Dudreuilh¹, S. Basu¹, O. Shaw², H. Burton¹, C. Domingo-Vila¹, T. Tree¹, G. Lombardi¹, C. Scotta¹, A. Dorling¹
¹King's College London, London, United Kingdom, ²Viapath Clinical Transplantation Laboratory, Guy's Hospital, London, United Kingdom
*Purpose: Highly sensitised patients exhibit poorer long-term outcomes following renal transplantation compared to those non sensitised individuals. IL17-A has been associated with acute rejection. Presence…
2022 American Transplant Congress
Center-Level Variation in Transplantation Practice Following Acuity Circles Policy Change
A. Burton¹, D. Goldberg²
¹University of Miami Miller School of Medicine, Miami, FL, ²Department of Gastroenterology, University of Miami Miller School of Medicine, Miami, FL
*Purpose: Although early studies suggest that the Acuity Circles (AC) allocation policy has reduced disparities in access to deceased donor liver transplants (DDLTs), changes in…
2022 American Transplant Congress
Natural Antibodies Are Associated With Rejection And Long-term Renal Allograft Loss In A Multi-center International Cohort
S. B. See¹, X. Yang², C. Burger³, B. Lamarthée⁴, R. Snanoudj⁵, R. Shihab¹, D. S. Tsapepas⁶, P. Roy¹, S. Larivière-Beaudoin⁷, K. Hamelin⁷, A. Mendoza Rojas⁸, N. M. van Besouw⁸, A. Bartosic⁹, N. Daniel⁹, E. R. Vasilescu¹⁰, S. Mohan¹¹, D. Cohen¹¹, L. Ratner¹¹, C. C. Baan⁸, J. S. Bromberg⁹, H. Cardinal⁷, D. Anglicheau³, Y. Sun², E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Biostatistics, Columbia University Irving Medical Center, New York, NY, ³Necker Hospital, Paris, France, ⁴Necker-Enfants Malades Institute, Paris, France, ⁵Bicêtre Hospital, Paris, France, ⁶Surgery, Columbia University Irving Medical Center, New York, NY, ⁷CHUM, Montreal, QC, Canada, ⁸Erasmus MC, Rotterdam, Netherlands, ⁹Surgery, University of Maryland School of Medicine, Baltimore, MD, ¹⁰Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ¹¹Medicine, Columbia University Irving Medical Center, New York, NY
*Purpose: Potentially harmful non-donor-specific human leukocyte antigen antibodies have been identified in renal transplantation, including natural IgG antibodies (Nabs) reactive to varied antigenic structures.*Methods: In…
2022 American Transplant Congress
Impact of Immunosuppressive Medications on SARS-CoV-2 Vaccination Response in Kidney Transplant Patients
O. Sogbein¹, A. Rizvi², M. Mujtaba³, M. Kueht⁴, J. Fair⁴, A. Gamilla-Crudo³, S. Hussain⁵
¹Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX, ²Internal Medicine, Nephrology, University of Texas Medical Branch at Galveston, Galveston, TX, ³University of Texas Medical Branch, Galveston, TX, ⁴Surgery, University of Texas Medical Branch, Galveston, TX, ⁵University of Texas Medical Branch, Houston, TX
*Purpose: The COVID-19 pandemic portends significant morbidity and mortality in immunocompromised individuals. Vaccination against COVID-19 among immunocompromised population is an essential step to minimize deadly…
2022 American Transplant Congress
Collaboration for Successful Transition to Adult Care in Liver Transplant: Early Outcomes of a Structured Program with Youth Engagement
B. Kosmach-Park¹, J. Kilpatrick², A. Algeo¹, K. Jones¹, L. Remaley¹, N. Elazzazy², N. Jonassaint³, G. Mazariegos¹
¹Transplant Surgery, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, ³Department of Medicine and Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA
*Purpose: To effectively transition youth to adult hepatology through a structured program and developed partnerships while promoting and maintaining optimal outcomes.*Methods: The pediatric and adult…
2022 American Transplant Congress
Immunomodulatory Effects of Probiotic Bifidobacterium Bifidum with Tacrolimus and Sirolimus in Mouse Skin Graft Model
A. Han¹, C. Chung², H. Kim³, H. Ko⁴, E. Jo¹, S. Min¹, S. Kim⁵, H. Park⁵, J. Ha¹
¹Seoul National University College of Medicine, Seoul, Korea, Republic of, ²Inha University Hospital, Incheon, Korea, Republic of, ³Korea University Guro Hospital, Seoul, Korea, Republic of, ⁴Kyung Hee University Hospital, Seoul, Korea, Republic of, ⁵Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea, Republic of
*Purpose: Accumulating evidence suggests that gut microbiota actively crosstalks with the host immune system, and alterations of gut microbiota may exert immune regulatory effects. We…
2022 American Transplant Congress
Covid-related Neonatal Cholestasis?: Liver Transplantation In Three Infants With Intrauterine Or Perinatal Covid Exposure
S. Sakhuja¹, K. Patel¹, N. T. Galvan²
¹Baylor College of Medicine, Houston, TX, ²Baylor College of Medicine, Houston, TX
*Purpose: The COVID pandemic presents a unique set of challenges during pregnancy including thromboembolic complications, direct placental infection, transplacental transmission, and systemic hyperinflammatory state. The…
2022 American Transplant Congress
A Novel National Program to Maximize Utilization of Lung and Heart Allografts from Donors After Brain Death (DBD) and Donors After Circulatory Death (DCD) for Transplantation
W. Hassanein, N. Dang, A. Hassanein, S. Brann, S. LaFrancesca, S. Reddy, M. Al Salihi, T. Khayal
Transmedics, Andover, MA
*Purpose: To build a national network of dedicated cardiothoracic surgical procurement and Organ Care System (OCS™) ex-vivo perfusion clinical experts to: Maximize cardiothoracic donor organ…