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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Racial Differences in HLA Mismatch Potential Among Kidney Registrations

    A. Robinson1, K. Lindblad1, D. Stewart1, J. Kim2, V. Casingal3, P. Lalli3, J. Lunz4, C. Murphey5, M. Pavlakis6

    1UNOS, Richmond, VA, 2Surgery, Keck Medicine of USC, Los Angeles, CA, 3Carolinas Medical Center, Charlotte, NC, 4LifeLink Foundation Transplant Immunology Lab, Tampa, FL, 5Southwest Immunodiagnostics, Inc., San Antonio, TX, 6Beth Israel Deaconess Med Ctr, Boston, MA

    *Purpose: HLA matched kidneys are associated with better long-term post-transplant graft survival. However, prioritizing patients well-matched with an available donor has historically resulted in disparities…
  • 2022 American Transplant Congress

    XR Tacrolimus Dosing By Ideal Body Weight Reduces Incidence Of Early Supratherapeutic Tacrolimus Concentrations

    G. Codispodo, J. Hedvat, D. Salerno, N. Lange

    Pharmacy, NewYork-Presbyterian Hospital, New York, NY

    *Purpose: At our center, the use of de novo Envarsus XR® (extended-release [XR] tacrolimus) dosed at 0.12 mg/kg is standard of care in adult kidney…
  • 2022 American Transplant Congress

    Baseline Levels and Early Post-Transplant Kinetics of Donor-Derived Cell-Free DNA Following Liver Transplantation

    S. Florman1, D. Axelrod2, J. Miles3, E. Vaskova3, D. Kilam3, K. Dhanireddy4, V. Subramanian4

    1Mount Sinai Medical Center, New York, NY, 2University of Iowa, Iowa City, IA, 3CareDx, South San Francisco, CA, 4Tampa General Hospital, Tampa, FL

    *Purpose: Non-invasive biomarkers in liver transplant (LT) are needed to improve detection of allograft injury in routine surveillance and during immunosuppression modulation, prior to the…
  • 2022 American Transplant Congress

    Single Center Early Experience with Urinary Multi Biomarker – Qsant

    Y. A. Qazi, W. Mon, C. Choi, M. Smogorzewski

    Keck Medical Center at USC, Los Angeles, CA

    *Purpose: QSant™, an urine-based test was recently introduced for detection of kidney transplant rejection. The test is being utilized at our center to help identify…
  • 2022 American Transplant Congress

    A Randomised Trial Of Normothermic Machine Perfusion Versus Static Cold Storage In Donation After Circulatory Death Renal Transplantation

    S. Hosgood1, C. Callaghan2, C. Wilson3, G. Oniscu4, B. Phillips5, L. Bates3, L. Smith6, M. L. Nicholson7

    1Surgery, University of Cambridge, Cambridge, United Kingdom, 2Transplant, Guys & St Thomas's, London, United Kingdom, 3Transplant, Freeman Hospital, Newcastle, United Kingdom, 4Edinburgh Royal Infirmary, Edinburgh, United Kingdom, 5Transplant, Guy's & St Thomas's, London, United Kingdom, 6NHSBT, NHSBT, Bristol, United Kingdom, 7University of Cambridge, Cambridge, United Kingdom

    *Purpose: Kidneys from donation after circulatory death (DCD) donors are more susceptible to cold storage injury and have a high risk of delayed graft function…
  • 2022 American Transplant Congress

    Transplant Centers That Assess Frailty as Part of Clinical Practice Have Better Outcomes

    X. Chen1, Y. Liu1, V. Thompson1, N. M. Chu1, E. A. King1, J. D. Walston2, J. A. Kobashigawa3, D. M. Dadhania4, D. L. Segev1, M. A. McAdams-DeMarco1

    1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, 3Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, 4Division of Nephrology and Hypertension, Weill Cornell Medicine, New York, NY

    *Purpose: Frailty predicts adverse post-kidney transplant (KT) outcomes, yet impacts of frailty assessments on center-level outcomes remain unclear. We tested whether transplant centers assessing frailty…
  • 2022 American Transplant Congress

    A Randomized, Controlled, Double-blind Trial Of Inulin To Boost Response To A Third Covid-19 Vaccine Dose In Kidney Transplant Recipients.

    J. Singer1, M. Tunbridge2, T. Salehi3, G. Perkins4, B. Grubnor-Bauk5, B. Sim3, T. Ying6, P. T. Coates3, S. J. Chadban1

    1Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia, 2Renal Medicine, Royal Adelaide Hospital, Adelaide, Australia, 3Royal Adelaide Hospital, Adelaide, Australia, 4School of Biological Sciences, University of Adelaide, Adelaide, Australia, 5Adelaide University, Adelaide, Australia, 6Royal Prince Alfred Hospital, Sydney, Australia

    *Purpose: Kidney transplant recipients (KTR) commonly exhibit inadequate responses to 2-dose COVID-19 vaccination schedules and remain at increased risk of severe COVID-19. Gut dysbiosis is…
  • 2022 American Transplant Congress

    Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study

    N. Sulejmani1, D. Axelrod2, S. Dholakia1, S. Shah3

    1CareDx, South San Francisco, CA, 2University of Iowa, Iowa City, IA, 3University of Cincinnati, Cincinnati, OH

    *Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
  • 2022 American Transplant Congress

    A Multicenter Randomized Controlled Trial To Compare The Efficacy Of Ex-vivo Machine Perfusion With Static Cold Storage In Human Liver Transplantation: The University Of Maryland Experience

    J. Avruch1, N. Goussous2, S. Malik1, M. Pinedo1, R. Meier1, C. Bhati1, D. Maluf1, R. Barth3, J. Alvarez-Casas1

    1Transplant Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Transplant Surgery, University of California Davis Health, Davis, CA, 3University of Chicago, Chicago, IL

    *Purpose: There is accumulating clinical evidence of the benefit of normothermic ex-vivo machine perfusion (NMP) compared with traditional static cold storage of liver allografts prior…
  • 2022 American Transplant Congress

    The Development of a Scientific Registry of Transplant Recipients Data Query Tool: A Human-Centered Design Process

    C. Schaffhausen1, A. Hart2, C. S. Zinner3, A. K. Israni2, J. Snyder1

    1Hennepin Healthcare Research Institute, Minneapolis, MN, 2Hennepin Healthcare (HHS) / University of Minnesota (UMN), Minneapolis, MN, 3Accenture Federal Services, Washington, DC

    *Purpose: The Scientific Registry of Transplant Recipients (SRTR) provides national transplant data in various forms, including the OPTN/SRTR Annual Data Report (ADR). The ADR includes…
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