Am J Transplant, Volume 22, Suppl 3 Archives - Page 142 of 190 - ATC Abstracts

2022 American Transplant Congress
External Validation of the Abbreviated Ibox Scoring System at One-Year Post Kidney Transplant as a Surrogate Endpoint for Death-Censored Graft Survival
A. Klein¹, L. Kosinski², R. Muse², A. Loupy³, O. Aubert³, G. Divard³, M. Stegall⁴, I. Helanterä⁵, W. E. Fitzsimmons¹, I. O'Doherty¹
¹Transplant Therapeutics Consortium, Critical Path Institute, Tucson, AZ, ²Critical Path Institute, Tucson, AZ, ³Paris Transplant Group, Paris, France, ⁴Mayo Clinic, Rochester, MN, ⁵Helsinki University Hospital, Helsinki, Finland
*Purpose: The Transplant Therapeutics Consortium seeks to translate the iBox from Loupy et al., 2019 into a surrogate endpoint for five-year death-censored graft survival after…
2022 American Transplant Congress
Performance of Race-Independent GFR Estimating Formulas, CKD-EPI₂₀₂₁and NMR-GFR Post Kidney Transplantation
E. Schiffer¹, F. Stammler², M. Grassi², E. Schiffer²
¹Clinical Research, numares Group Corporation, Boston, MA, ²Research and Development, numares AG, Regensburg, Germany
*Purpose: Progressive GFR decline post kidney transplantation is a general problem that requires accurate assessment of GFR for clinical decision making. The gold-standard radiotracer determined…
2022 American Transplant Congress
CIAT: A New Kidney Exchange Program with Better Options for Highly Sensitized and Long Waiting Patients
M. d. Klerk¹, J. Kal¹, D. L. Roelen², M. Betjes¹, A. Weerd de¹, M. Reinders¹, M. Kho¹, K. Glorie³, J. I. Roodnat¹
¹Internal Medicine, Erasmus MC Transplant Institute, Rotterdam, Netherlands, ²Immunology, Leids UMC, Netherlands, ³Econometrics, EUR, Rotterdam, Netherlands
*Purpose: A number of alternative, both living and deceased donor kidney transplant programs have been developed for incompatible pairs and difficult to match patients. The…
2022 American Transplant Congress
Racial Equity in Living Donor Kidney Transplant: Center Variation and Opportunities for Progress
L. M. McElroy, T. Schappe, S. Peskoe, V. Wang, D. Mohottige, C. D. Scales, J. Pendergast, L. Boulware
Duke University, Durham, NC
*Purpose: To estimate racial differences in living donor kidney transplant (LDKT) rates relative to patient, center and regional characteristics that may influence access to transplant.*Methods:…
2022 American Transplant Congress
Reduced Enterohepatic Recirculation of Mycophenolate and Lower Blood Concentrations Are Associated with the Stool Bacterial Microbiome
P. A. Jacobson¹, A. Saqr¹, B. Carlson¹, C. Staley², A. Rashidi³, S. Holtan³, M. Al-Kofahi¹, T. Kaiser², M. MacMillan⁴, J. Young⁵, N. El Jurdi³, D. Weisdorf³, A. Khoruts⁶
¹Univ of MN, College of Pharmacy, Minneapolis, MN, ²Univ of MN, Dept of Surgery, Minneapolis, MN, ³Univ of MN, Divison of Heme/Onc Transplant, Minneapolis, MN, ⁴Univ of MN, Pediatric Heme/Onc Transplant, Minneapolis, MN, ⁵Univ of MN, Divison of Infectious Diseases, Minneapolis, MN, ⁶Univ of MN, Division of Gastroenterology, Hepatology and Nutrition, Minneapolis, MN
*Purpose: Mycophenolate mofetil (MMF) is an important immunosuppressant used after allogeneic hematopoietic cell transplant (HCT). Blood concentrations of mycophenolic acid (MPA) are highly variable and…
2022 American Transplant Congress
Blood Transcriptomes of Covid-19 Infected Kidney Recipients Demonstrate Frequent and Persistent Sars-cov-2 Virome Gene Expression
Z. Sun¹, M. M. Rana², A. C. Reghuvaran³, Y. A. Azzi⁴, G. Carrara⁵, S. Hartzell⁶, S. Kulkarni³, W. Zhang⁶, K. Banu³, P. Heeger⁶, E. Akalin⁴, P. Cravedi⁶, Z. Zhang⁷, M. C. Menon³
¹Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, ²Infectious Disease Director, Icahn School of Medicine at Mount Sinai, New York, NY, ³Nephrology, Yale University, New Haven, CT, ⁴Nephrology, Montefiore Medical Center, New York, NY, ⁵Clinical Research Coordinator, Icahn School of Medicine at Mount Sinai, New York, NY, ⁶Icahn School of Medicine at Mount Sinai, New York, NY, ⁷Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Kidney transplant recipients (KTRs) have poor outcomes vs non-KTRs with acute COVID-19. To provide insight into management of immunosuppression during acute COVID-19, we studied…
2022 American Transplant Congress
Management of Hepatitis B Positive Donors in Liver Transplant
M. Tilley¹, T. A. Sparkman², K. Gutierrez²
¹Pharmacy, UAB, Birmingham, AL, ²UAB, Birmingham, AL
*Purpose: In an effort to expand the pool of solid organ transplant donors, patients with end stage liver disease may receive an organ from a…
2022 American Transplant Congress
B and Plasma Cell Populations Drive Chronic Rejection After Lung Transplantation
M. Bueno¹, N. F. Smirnova², K. Riemondy³, P. Suresh¹, M. Brown¹, X. Wang¹, S. Collins⁴, J. Sembrat¹, M. Koenigshoff¹, M. Snyder¹, J. McDyer¹, O. Eickelberg¹
¹Pulmonary and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, ²I2MC, INSERM UMR1297, Toulouse, France, ³Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, ⁴Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO
*Purpose: Chronic lung allograft dysfunction (CLAD) remains the major determinant of morbidity and mortality post-lung transplantation (LTx). Bronchiolitis obliterans syndrome (BOS) is the most prevalent…
2022 American Transplant Congress
Seroprevalence of MMR and Varicella (MMRV) in Solid Organ Transplant Candidates and Seroresponse to MMRV Vaccinations
H. Javaid¹, R. Hasbun¹, A. DeGolovine², S. Jyothula³, V. Machicao⁴, J. Bynon⁵, L. Ostrosky¹, M. Nigo¹
¹Division of Infectious Diseases, McGovern Medical School, University of Texas Health Science Center, Houston, TX, ²Div of Renal Disease, Univ of Texas Health Science Center, Houston, TX, ³Div of Advanced Heart Failure and Transplant Cardiology, Univ of Texas Health Science Center, Houston, TX, ⁴Div of Transplant Hepatology, Univ of Texas Health Science Center, Houston, TX, ⁵Div of Immunology and Organ Transplantation, Univ of Texas Health Science Center, Houston, TX
*Purpose: Updating live vaccines such as MMR and varicella (MMRV) is an important step in preparing patients during the pre-solid organ transplant (SOT) period. While…
2022 American Transplant Congress
Long-Term Follow Up of Solid Organ Transplantation Using Hepatitis C Virus Positive Donor for Hepatitis C Virus Negative Recipients
H. Sogawa¹, I. Lee², K. Okumura³, R. Bodin⁴, D. C. Wolf⁴, B. Partiula⁴, A. Dhand⁴, M. Kai⁵, S. Ohira⁵, R. Misawa¹, G. Veillette⁶, D. John¹, S. Nishida⁷, T. Diflo⁶
¹Division of Intra-abdominal Organ Transplant, Department of Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, ²Department of Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, ³Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁴Department of Medicine, Westchester Medical Center/ New York Medical College, Valhalla, NY, ⁵Cardiothoracic Surgery, Westchester Medical Center/ New York Medical College, Valhalla, NY, ⁶Westchester Medical Center, Valhalla, NY, ⁷Westchester Medical Center/ New York Medical College, Valhalla, NY
*Purpose: To determine the effects of transplanting an HCV + solid organ to an uninfected patient who is on the transplant waiting list. Outcomes include…