ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Locoregional Therapy for Hepatocellular Carcinoma Decreases Liver Transplant Waitlist Dropout and Mortality

    S. Weeks, T. Ishaque, A. Massie, D. Segev, E. King

    Johns Hopkins, Baltimore, MD

    *Purpose: Liver transplant candidates with hepatocellular carcinoma (HCC) risk tumor progression that may disqualify them from transplant eligibility while awaiting HCC exception points on the…
  • 2022 American Transplant Congress

    Excellent Long-Term Outcome of ABO-Incompatible Living Kidney Transplantation by Reduced-Session of Plasmapheresis of Desensitization Protocol

    Y. Ishiyama1, K. Tanabe2, T. Kanzawa2, K. Unagami2, H. Ishida2, T. Takagi2

    1Urology, Tokyo Women's Medical University Medical Center East, Arakawa, Japan, 2Tokyo Women's Medical University, Tokyo, Japan

    *Purpose: Plasmapheresis (PE) is applied to ABO-incompatible living kidney transplantation (ABOi-LKT) in order to remove ABO blood type antibody to obtain the appropriate target levels.…
  • 2022 American Transplant Congress

    Growing Use of Perfusion for Heart, Liver, and Lung and Early Outcomes

    R. R. Goff1, K. Gauntt1, W. Cherikh1, E. D. Lease2, D. Klassen1

    1United Network for Organ Sharing, Richmond, VA, 2University of Washington, Seattle, WA

    *Purpose: In 2015 the OPTN began collecting data on perfusion for heart, liver, and lung deceased donors (DD) on the DD registration form. Since 2015,…
  • 2022 American Transplant Congress

    HDAC Inhibitors Suppress Endothelial Inflammation but Alter Identity

    N. M. Valenzuela

    Pathology and Laboratory Medicine, UCLA, Los Angeles, CA

    *Purpose: Histone modifications such as acetylation control gene expression. Histone deacetylases (HDACs) have been proposed as an attractive therapeutic approach to counteract detrimental gene expression,…
  • 2022 American Transplant Congress

    Sars-cov-2 Antibodies Transitions After Vaccination In Solid Organ Transplant Recipients: Multicenter Study In Japan

    K. Unagami1, M. Yoshikawa2, Y. Natori3, K. Omoto1, H. Ishida1, H. Date4, R. Imamura5, T. Ito4, K. Miyaji6, S. Takahara7, K. Yuzawa8, O. Satoko9, Y. Hirota10, H. Egawa1

    1Tokyo Women's Medical University, Tokyo, Japan, 2Kyoto Prefectural University of Medicine, Kyoto, Japan, 3University of Miami, Pinecrest, FL, 4Kyoto University, Kyoto, Japan, 5Dept. of Urology, Osaka Univ. Graduate School of Medicine, Suita, Japan, 6Renal Transplantation, Takatsuki General Hospital, Takatsuki, Japan, 7Kansai Medical Hospital, Toyonaka, Japan, 8Tranplantation Surgery, National Hospital Organization Mito Medical Center, Mito, Japan, 9Public Health, Osaka City University Graduate School of Medicine and Research Center for Infectious, Osaka City University Graduate School of Medicine, Osaka, Japan, 10Clinical Epidemiology Research Center, Miyama, Japan

    *Purpose: For purpose of SARS-CoV-2 infection control, vaccination was started in worldwide, however, low reactivity of antibody production after vaccination is a concern for solid…
  • 2022 American Transplant Congress

    Pancreas Transplants Outcomes in Diabetes Mellitus Type 1 and Type 2 in the 21st Century: Are They Two Different Populations?

    M. Merzkani1, H. Murad2, M. Wang1, V. Hu1, M. Ji3, Y. Al-Hosni1, O. Alzahabi1, M. Zayed1, J. Wellen4, K. Lentine5, S. Chang6, T. Alhamad7

    1Washington University, St Louis, MO, 2Washington University in St Louis, Chesterfield, MO, 3Washington University in St. Louis School of Medicine, Saint Louis, MO, 4Washington University School of Medicine, Saint Louis, MO, 5SLU, St Louis, MO, 6Surgery, Washington University School of Medicine, Saint Louis, MO, 7Washington University School of Medicine at St. Louis, Saint Louis, MO

    *Purpose: Pancreas alone transplant (PT) has been associated with decreased progression and regression of microvascular and macrovascular complications. In this current era of standardized immunosuppression,…
  • 2022 American Transplant Congress

    Estimating the Effect of Increased Donor Heart Ischemic Time on Post-Transplant Survival Using Instrumental Variables

    G. Ran1, K. Lazenby1, N. Narang2, W. F. Parker3

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Department of Medicine, University of Illinois-Chicago, Chicago, IL, 3Department of Medicine, University of Chicago, Chicago, IL

    *Purpose: Isolate the impact of organ ischemic time on post-transplant survival using the recent change in heart allocation policy as a natural experiment.*Methods: We examined…
  • 2022 American Transplant Congress

    Prospective Analysis of the Impact of Impella 5.5 Devices on HLA Antibody Development in Transplant Recipients

    K. Castro, J. Van Zyl, R. Doss, S. McKean, J. Russelia, A. Alam, M. Askar, S. Hall

    Heart and lung Transplant Research, Baylor University Medical Center, Dallas, TX

    *Purpose: Little is known about the development of Human Leukocyte Antigen antibodies with the use of the new Impella 5.5 temporary mechanical circulatory assist device.*Methods:…
  • 2022 American Transplant Congress

    The Paradox of Lifestyle – Related Liver Disease: ASH and NASH

    N. Kemmer1, J. Buggs2

    1Transplant Hepatology, Tampa General Hospital, Tampa, FL, 2Transplant Surgery, Tampa General Hospital, Tampa, FL

    *Purpose: In the last decade, the burden of lifestyle-related chronic disease has been on the rise and is considered a growing serious public health concern.…
  • 2022 American Transplant Congress

    Circulating Donor-Derived Cell-Free DNA: A Novel Non-Invasive Biomarker for Immune Surveillance in Vascularized Composite Allotransplantation

    W. J. Rifkin1, J. Trilles1, P. S. Rabbani1, O. C. Onuh1, B. E. Gelb2, D. J. Ceradini1, E. D. Rodriguez1

    1Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY, 2Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: The purpose of this study is to evaluate whether circulating donor-derived cell-free DNA (dd-cfDNA) could be used as a noninvasive biomarker to detect rejection…
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