Am J Transplant, Volume 22, Suppl 3 Archives - Page 139 of 190 - ATC Abstracts

2022 American Transplant Congress
Pegylated Lacritin N-104 Promotes Mouse Islet Stabilization and Prevents Diabetes Progression in the Non-Obese Diabetic (NOD) Mouse Model
M. Ma¹, P. Chhabra¹, G. Laurie², K. L. Brayman¹
¹Department of Surgery, University of Virginia Health System, Charlottesville, VA, ²Department of Cell Biology, University of Virginia Health System, Charlottesville, VA
*Purpose: To investigate if PEGylated Lacritin N-104 (PEG N-104) prevents the progression of type 1 diabetes (T1D) in the NOD mouse.*Background: Lacritin is a multifunctional…
2022 American Transplant Congress
Lucas Device Assisted Uncontrolled Dcd Kidney Transplantation – A Feasible but Underutilized Option in the United States
S. Nagaraju, S. Vaishnav, R. Savilla, M. Moore, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: Uncontrolled DCD (uDCD) procurement involves either normo-thermic or hypothermic regional perfusion to reduce ischemic injury. We report a series of successful kidney transplant utilizing…
2022 American Transplant Congress
Dual Deceased Donor Kidney Transplants: Maximizing Utilization of Suboptimal Kidneys
S. Nagaraju, S. Vaishnav, K. Boggs, T. Cook, A. Jones, J. B. Africa
Renal Transplant, Charleston Area Medical Center, Charleston, WV
*Purpose: To demonstrate that dual transplant of marginal kidneys is an underutilized strategy to minimize discard rates and mitigate organ shortage.*Methods: We compared dual kidney…
2022 American Transplant Congress
A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions
C. Schaffhausen¹, A. Hart², S. Chu³, A. K. Israni², J. Synder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare / University of Minnesota, Minneapolis, MN, ³University of Minnesota, Saint Paul, MN
*Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…
2022 American Transplant Congress
Expanded Criteria Donor with Severe Acute Kidney Injury: Worth to Use?
S. Thotsiri, N. Sutharattanapong, C. Janphram, P. Wiwattanathum
Excellent Center of Organ Transplantation, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
*Purpose: Because of organ shortage, the world facing problem, expanded criteria donor (ECD) was utilized to increase donor pool. Although long term allograft survival from…
2022 American Transplant Congress
Impact of Recipient Obesity on Kidney Transplantation Outcome: A Retrospective Cohort Study with a Matched Comparison
A. Buemi
Surgery, Cliniques Universitaires Saint Luc, Bruxelles, Belgium
*Purpose: The aim of this study was to evaluate the effect of recipient obesity on posttransplant complications and patient and graft survival.*Methods: A single-institution, retrospective…
2022 American Transplant Congress
Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study
A. Abdellatif¹, L. Zhao², K. Cherny², B. Marder², J. D. Scandling³, K. Saag⁴
¹Division of Nephrology, Baylor College of Medicine, Houston, TX, ²Horizon Therapeutics PLC, Deerfield, IL, ³Division of Nephrology, Stanford School of Medicine, Stanford, CA, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
2022 American Transplant Congress
Long-Term Clinical Outcomes in ABO Incompatible Kidney Transplantation in Patients with High Baseline Anti-A/B Antibody Titer
S. Eum¹, H. Lee¹, E. Ko¹, H. Yoon², S. Shin², C. Yang¹, B. Chung¹
¹Division of Nephrology, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ²Division of Nephrology, Department of Internal Medicine, Incheon St. Mary's Hospital, Incheon, Korea, Republic of
*Purpose: ABO incompatible (ABOi) kidney transplantation (KT) has been considered to overcome donor shortage. We investigated the long-term clinical outcomes in ABOi KT in patients…
2022 American Transplant Congress
Sars-cov-2 Antibody and T Cell Response After Vaccination with or without Intensified Immunosuppression Among Pediatric Renal Transplant Recipients
H. Pizzo¹, B. Shin², P. R. Soni³, S. Nadipuram³, J. Garrison², R. Zhang², S. C. Jordan², D. Puliyanda¹
¹Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA, ³Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Recent data has shown poor antibody response to SARS-CoV-2 vaccination among adult kidney transplant (tx) recipients, with seroconversion ranging between 22%-58% after two mRNA…
2022 American Transplant Congress
Impact of Belatacept Conversion on Renal Function and Donor Specific Antibodies in Renal Transplant Recipients
E. R. Brown, K. Cunningham, K. Paplaczyk, C. Dagostino, C. Kane, A. Shetty
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Although associated with nephrotoxicity, calcineurin inhibitors (CNI) have historically been the cornerstone of immunosuppression. Belatacept, a co-stimulation blocker, is FDA-approved for de novo use…