Am J Transplant, Volume 22, Suppl 3 Archives - Page 134 of 190 - ATC Abstracts

2022 American Transplant Congress
Individual and Community-Level Social Determinants of Health in Liver Transplant
M. Yilma¹, R. Cogan², N. Mehta³, J. Neuhaus², J. Voelkel⁴, C. Light⁵, I. Allen², R. Hirose²
¹General Surgery, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA, ³UCSF, San Francisco, CA, ⁴Kaiser Permanente Northern California, San Francisco, CA, ⁵UCSF Medical Center, San Francisco, CA
*Purpose: To investigate the individual and census-level social determinants of health on liver transplant listing.*Methods: Retrospective review of patients referred to the University of California…
2022 American Transplant Congress
Novel Phenotype of Intragraft Endothelial Cells That Modulates CD4⁺ T Effector-Mediated Rejection
J. Wedel, K. Liu, T. Seto, S. Kong, D. M. Briscoe
Boston Children's Hospital, Boston, MA
*Purpose: Previous studies have suggested that early adoptive transfer of Teff into Rag KO mice bearing cardiac transplants results in acute rejection. However, if transfer…
2022 American Transplant Congress
25-Year Risk of ESRD Among Living Kidney Donors
J. Wainright¹, A. Robinson¹, A. Wilk¹, D. Klassen², W. Cherikh¹, D. Stewart¹
¹Research, UNOS, Richmond, VA, ²Office of the Chief Medical Officer, UNOS, Richmond, VA
*Purpose: Previous research on post-donation ESRD in living kidney donors (LKDs) has been limited by short follow-up time, the small number of ESRD cases available…
2022 American Transplant Congress
Donor-Derived Cell-Free DNA as a Biomarker of T Cell Mediated Rejection in Pediatric Kidney Transplant Patients
R. Dandamudi¹, S. Federman², R. Woodward², S. Dholakia², L. Walther¹, V. Dharnidharka¹
¹Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, ²CareDx, Brisbane, CA
*Purpose: T-cell-mediated rejection (TCMR) is a major cause of kidney allograft failure which requires kidney biopsy for a definitive diagnosis. Donor-derived cell-free DNA (dd-cfDNA) is…
2022 American Transplant Congress
Long-Term Outcomes of Crossmatch Positive Simultaneous Liver Kidney Transplants in the United States
S. Riad¹, E. Aby¹, S. Jackson², P. Nguyen³, N. Lim¹, J. Lake¹
¹Medicine, University of Minnesota, Minneapolis, MN, ²Mhealth-Fairview, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN
*Purpose: The long-term results of crossmatch positive (XM+) simultaneous liver-kidney (SLK) transplants are conflicting. We examined the association between crossmatch (XM) status and SLK outcomes…
2022 American Transplant Congress
Outcomes of a Standardized Antibody-Mediated Rejection (AMR) Treatment Protocol in Heart Transplant Recipients (HTR)
J. Lee, T. Sam, J. Van Zyl, S. Mckean, L. Fuller, N. Wilson, A. Dao, R. Gottlieb, S. Hall, R. Patel
Baylor University Medical Center, Dallas, TX
*Purpose: AMR in HTR portends poor clinical outcomes. Reported mortality range between 20-50%, with higher rates reported for late AMR occurring at least 1 year…
2022 American Transplant Congress
Donor Derived Transmissions 2020: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC) with a Focus on COVID-19
R. M. La Hoz¹, A. Agarwal¹, G. Berry¹, K. Dunn¹, J. Goldman¹, S. Ho¹, M. Kittleson¹, D. H. Lee¹, D. J. Levine¹, C. Marboe¹, G. Marklin¹, S. Pouch¹, R. Razonable¹, S. Taimur¹, H. Te¹, A. Woolley¹, C. Fox², C. Jett², S. Booker², D. K. Klassen², L. Danziger-Isakov¹
¹OPTN DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: The OPTN DTAC, a multidisciplinary group, evaluates potential donor derived transmission events (PDDTE) to assess the likelihood of disease transmission.*Methods: Retrospective study of PDDTE…
2022 American Transplant Congress
Pd-1 Licenses Activated Treg for Lymphatic Migration
W. Piao¹, L. Li¹, V. Saxena¹, K. Hippen², M. Shirkey¹, B. Blazar², I. Lape³, y. zhang³, J. Bromberg¹
¹Surgery, University of Maryland, Baltimore, MD, ²University of Minnesota, Minneapolis, MN, ³Harvard Medical School, Boston, MA
*Purpose: In addition to serving as fluid conduits, lymphatic vessels are critical portals for immune cell migration. Lymphatic endothelial cells (LECs) constitutively express high levels…
2022 American Transplant Congress
Type 1 Innate Lymphoid Cells Alleviate Acute Liver Injury Following Transplantation via Interferon-γ Mediated Pathway
H. Kojima, K. Kadono, H. Hirao, K. J. Dery, J. Kupiec-Weglinski, Y. Zhai
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Innate lymphoid cells (ILCs), a heterogeneous population of non-B non-T lymphocytes, have been found in recent years to plays key regulatory roles in tissue…
2022 American Transplant Congress
Post-Transplant Lymphoproliferative Disorder in Kidney and Simultaneous Pancreas and Kidney Transplant Recipients Predictors, and Patient and Allograft Outcomes
M. A. Mohamed¹, E. A. Yousif¹, V. Manchala², F. Aziz³, N. Garg⁴, S. Parajuli⁴, D. Mandelbrot⁵, B. Astor¹
¹Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, ²Medicine-Transplant Nephrology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³University of Wsiconsin, Madison, WI, ⁴University of Wisconsin, Madison, WI, ⁵UW Health, Madison, WI
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a devastating complication following kidney and pancreas transplantation. 12% of UNOS waitlisted candidates had previous transplant and 20% are…