Am J Transplant, Volume 22, Suppl 3 Archives - Page 133 of 190 - ATC Abstracts

2022 American Transplant Congress
Predictors of Response to Belatacept Conversion in Kidney Transplant Patients with Chronic Active Antibody-Mediated Rejection
D. Kumar¹, R. Winstead¹, H. Iftikhar¹, R. Minniti¹, S. Khorsandi¹, J. Christensen¹, I. Yakubu¹, I. Moinuddin¹, L. Kamal¹, P. Halloran², G. Gupta¹
¹Virginia Commonwealth University, Richmond, VA, ²University of Alberta, Edmonton AB, AB, Canada
*Purpose: Chronic active antibody mediated rejection (cABMR) is a major cause of kidney transplant (KT) loss. Current therapies have unclear efficacy and side effects. We…
2022 American Transplant Congress
Variation in Adult Living Donor Liver Transplantation in the United States: Identifying Opportunities for Increased Utilization
K. Lentine¹, D. Axelrod², M. Schnitzler¹, R. Li¹, M. Dew³, T. Bitterman⁴, K. Olthoff⁴, J. Locke⁵, S. Emre⁶, H. Hunt⁷, T. Tanaka², A. Liapakis⁶
¹Saint Louis University, St. Louis, MO, ²U Iowa, Iowa City, IA, ³U Pittsburgh, Pittsburgh, PA, ⁴U Penn, Philadelphia, PA, ⁵UAB, Birmingham, AL, ⁶Yale, New Haven, CT, ⁷UNOS, Richmond, VA
*Purpose: To assess barriers to living donor liver transplant (LDLT) access in light of convincing evidence of survival benefits for patients with end-stage liver disease.*Methods:…
2022 American Transplant Congress
Prescription Opioid Use May be More Detrimental to Younger Kidney Transplant Recipients: A Machine Learning Approach
J. Kim¹, S. Bae¹, J. Ahn¹, K. Lentine², D. Segev¹, M. McAdams-DeMarco¹
¹Johns Hopkins, Baltimore, MD, ²Saint Louis University, St. Louis, MO
*Purpose: Prescription opioid use requires special attention in kidney transplant (KT) recipients considering that it increases the risk of death and graft loss. However, the…
2022 American Transplant Congress
Ex Vivo Modification of Vascular Allografts Using Immunosuppressive and Anti-Inflammatory Polymers Prevent Rejection via Localized Immunosuppression
H. D. Luo¹, E. M. Siren¹, W. Enns², L. Sim¹, C. Du¹, S. G. Withers¹, J. Choy³, J. N. Kizhakkedathu¹
¹The University of British Columbia, Vancouver, BC, Canada, ²Simon Fraser University, Burnaby, BC, Canada, ³Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
*Purpose: Classical immunosuppressants lead to systemic immune shutdown, though necessary to mediate transplant rejection, it may lead to various complications. To reduce off-target immunosuppression while…
2022 American Transplant Congress
Targeting the Bet Family Protein Brd4 Inhibits Inflammatory Macrophages and Promotes Heart Allograft Tolerance
X. Xiao
Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Infiltration of allografts by inflammatory macrophages is frequently associated with chronic graft loss In both animal models and clinical settings, but the mechanisms that…
2022 American Transplant Congress
Outcomes of Hlai Kidney Transplants in Patients with Cpra 100% After Desensitization
A. A. Vo¹, J. Tang¹, S. Williamson¹, C. Meyers¹, E. Huang¹, X. Zhang², M. Haas³, A. Peng¹, R. Najjar¹, S. Supreet¹, N. Ammerman¹, K. Lim¹, M. Gillespie¹, N. Badash¹, S. Jordan¹
¹Comprehensive Transplant Center, Cedars Sinai Medical Ctr, Los Angeles, CA, ²HLA Laboratory, Cedars Sinai Medical Ctr, Los Angeles, CA, ³Pathology, Cedars Sinai Medical Ctr, Los Angeles, CA
*Purpose: The KAS implementation was aimed at increasing access to kidney transplantation in highly HLA sensitized (HS) patients. However, combining desensitization (DES) + KAS could…
2022 American Transplant Congress
18 Month Impact of the National Liver Review Board
J. Foutz¹, S. Noreen¹, K. Bradbrook², M. Cafarella¹, J. Pomposelli³, S. Biggins⁴, J. Trotter⁵
¹United Network for Organ Sharing, Richmond, VA, ²Research, United Network for Organ Sharing, Richmond, VA, ³University of Colorado, Aurora, CO, ⁴University of Washington, Seattle, WA, ⁵Baylor University Medical Center, Dallas, TX
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2022 American Transplant Congress
Delayed Graft Function in Living Donor Kidney Transplantation: Risk Factors and Outcomes
G. Defelice¹, A. Paramesh², H. Jeon², K. Atiemo², M. Killackey², A. Vijay²
¹Tulane University School of Medicine, New Orleans, LA, ²Transplant Surgery, Tulane University School of Medicine, New Orleans, LA
*Purpose: Delayed graft function (DGF) following living donor kidney transplantation is less common and long-term outcomes are less understood. This single-center retrospective analysis of living…
2022 American Transplant Congress
Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine
F. Villanego¹, M. Crespo², V. Lopez³, S. Zarraga⁴, F. Oppenheimer⁵, L. Llinas², A. Andres⁶, C. Diaz⁷, M. Ruiz⁸, F. Moreso⁹, A. Rodriguez-Benot¹⁰, I. Beneyto¹¹, S. Cabello¹², C. Jimenez¹³, C. Canal¹⁴, M. Molina¹⁵, J. Pascual⁶, A. Mazuecos¹
¹Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ²Department of Nephrology, Hospital del Mar, Barcelona, Spain, ³Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, ⁴Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, ⁵Department of Nephrology, Hospital Clinic, Barcelona, Spain, ⁶Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, ⁷Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, ⁸Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ⁹Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, ¹⁰Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, ¹¹Department of Nephrology, Hospital La Fe, Valencia, Spain, ¹²Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, ¹³Department of Nephrology, Hospital La Paz, Madrid, Spain, ¹⁴Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, ¹⁵Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain
*Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
2022 American Transplant Congress
Identification of a Human B Cell State with Allogeneic Antigen Cross-Presenting Potential
U. Bhatia, E. C. Guinan
Radiation Oncology, Dana-Farber Cancer Institute, Boston, MA
*Purpose: B cells are known to play a significant role in allograft tolerance or rejection, largely determined by production of cytokines and antibodies that suppress…