Am J Transplant, Volume 22, Suppl 3 Archives - Page 127 of 190 - ATC Abstracts

2022 American Transplant Congress
Factors Predicting Early Extubation After Liver Transplantation
V. Subramanian¹, O. Bishr², J. Buggs¹, N. Kemmer¹, K. Dhanireddy¹
¹Transplant Institute, Tampa General Hospital, Tampa, FL, ²University of South Florida, Tampa, FL
*Purpose: Early extubation (either intraoperative or within 6 hours post operatively) is an important component of enhanced recovery pathways. The goal of the study was…
2022 American Transplant Congress
Risk Factors Associated with Medium-Term Allograft and Recipient Survival: Learned from 1,587 Adults with Single Kidney Transplantation
S. Chang¹, B. Liu¹, D. Du¹, N. Gong², L. Zhu¹, G. Chen¹, W. Zhang¹, Z. Chen²
¹Institute of Organ Transplantation,Tongji Hospital,Tongji Medical College,HUST, Wuhan, China, ²Huazhong University of Science and Technology, Wuhan, China
*Purpose: Retrospectively investigated the reason for graft failure during the perioperative period and discussed whether DGF and the high SCr level in a short time…
2022 American Transplant Congress
Comparison of Perioperative Antibiotic Prophylaxis Regimens on Surgical Site Infections in Pancreas Transplant Recipients
Z. A. Yetmar¹, M. McCord², B. Lahr³, A. Lemke², P. G. Dean⁴, Y. C. Kudva⁵, M. T. Seville⁶, W. Bosch⁷, S. A. Bernard², E. Beam¹
¹Division of Infectious Diseases, Mayo Clinic, Rochester, MN, ²Department of Pharmacy, Mayo Clinic, Rochester, MN, ³Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, ⁴Division of Transplantation Surgery, Mayo Clinic, Rochester, MN, ⁵Division of Endocrinology, Diabetes, Metabolism & Nutrition, Mayo Clinic, Rochester, MN, ⁶Division of Infectious Diseases, Mayo Clinic, Scottsdale, AZ, ⁷Division of Infectious Diseases, Mayo Clinic, Jacksonville, FL
*Purpose: Pancreas transplant recipients are at high risk of surgical site infection (SSI), with rates ranging from 9-45%. Several risk factors for SSI have been…
2022 American Transplant Congress
Perturbations in Podocyte Transcriptome and Biological Pathways Induced by Injury Caused by FSGS Associated Circulating Factors
P. Rashmi¹, T. Sigdel¹, D. Rychkov¹, I. Damm¹, F. Vincenti¹, C. Craik¹, J. Reiser², M. Sarwal¹
¹UCSF, San Francisco, CA, ²Rush University, Chicago, IL
*Purpose: Focal segmental glomerulosclerosis (FSGS) remains a disease without specific therapy for primary disease and a high rate of recurrence after renal transplant. Circulating factors…
2022 American Transplant Congress
Deficiency of Antibody-Suppressor CXCR5⁺CD8⁺ TCells (Not CD4⁺ T_regs) Drive High Alloantibody Production in CCR5 KO Kidney Transplant Recipients
J. L. Han¹, J. M. Zimmerer¹, Q. Zeng², S. Chaudhari¹, C. K. Breuer², G. L. Bumgardner¹
¹Dept of Surgery, The Ohio State University, Columbus, OH, ²Center for Regen. Med., The Research Institute at Nationwide Children's Hospital, Columbus, OH
*Purpose: Kidney transplant (KTx) into CCR5 KO mice is an excellent model to study AMR immunobiology due to high alloantibody (alloAb) production, rapid allograft rejection,…
2022 American Transplant Congress
Understanding the Heterogeneity of Alloreactive Natural Killer (NK) Cell Function in Kidney Transplant Recipients
D. Ruan, M. Fribourg, N. Chun, P. Cravedi, A. Horowitz, P. Heeger
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Emerging evidence indicates that human NK cells are a heterogeneous population of lymphocytes that are activated upon ligation of one or more activating receptors…
2022 American Transplant Congress
Bone Marrow Resident Long-Lived Plasma Cells as Source of Chronic Donor-Specific Antibodies
M. Muckenhuber, S. Pichler, A. M. Weijler, T. Wekerle
Dept. of General Surgery, Div. of Transplantation, Medical University of Vienna, Vienna, Austria
*Purpose: The importance of bone marrow resident plasma cells for long-lasting humoral immunity has been highlighted in several models for vaccination and infectious diseases. To…
2022 American Transplant Congress
A Sustained Injury Response by Regulatory T Cells (Treg) Contributes to Fibrosis to Promote Chronic Rejection After Heart Transplantation
J. Bou Saba¹, L. Fan¹, X. Zhang¹, T. Li¹, L. R. Mathews¹, G. Dwyer², E. Colon², M. J. Calderon³, K. E. Helfrich³, M. A. Ross³, S. C. Watkins³, H. Turnquist¹
¹Surgery, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ²Immunology, University of Pittsburgh, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, ³Cell Biology, University of Pittsburgh, Center for Biologic Imaging, Pittsburgh, PA
*Purpose: Chronic rejection (CR) results from the development of immunosuppressant-resistant allograft vasculopathy and fibrosis and remains a leading cause of recipient death one-year post-heart transplant…
2022 American Transplant Congress
Characterization of Hepatocytes During Cold Static Preservation at Single Cell Resolution
S. Naik¹, M. Dogan¹, C. Watkins¹, A. Bajwa¹, C. Eymard², J. Eason³, C. Kuscu¹, C. Kuscu¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ³University of Tennessee/Methodist Transplant Institute, Memphis, TN
*Purpose: Hepatocytes together with liver sinusoidal endothelial cells (LSEC) are the most affected cells during cold preservation of donor liver. Necrotic and apoptotic hepatocytes release…
2022 American Transplant Congress
A Single Center Experience of Simultaneous Heart-Kidney Transplantation
A. Samra¹, A. Mattoo²
¹Nephrology, New York University Langone Transplant Institute, New York, NY, ²New York University Langone Transplant Institute, New York, NY
*Purpose: Currently there are no UNOS guidelines regarding the selection criteria required for simultaneous heart-kidney transplant recipients (SHKT). As of 2018 our center has begun…