Am J Transplant, Volume 22, Suppl 3 Archives - Page 127 of 190 - ATC Abstracts

2022 American Transplant Congress
Association of Trugraf GEP with Clinical and Histological Outcomes in a Multicenter Cohort (TOGETHER Study)
R. Heilman¹, W. Park², M. Mai³, B. Smith², R. First⁴, J. Fleming⁴, P. West-Thielke⁴, J. Holman⁴, M. Stegall²
¹Mayo Clinic, Phoenix, AZ, ²Mayo Clinic, Rochester, MN, ³Mayo Clinic, Jacksonville, FL, ⁴Transplant Genomics, Framingham, MA
*Purpose: The purpose of this study was to validate the association of TruGraf GEP with clinical endpoints in a real-world cohort.*Methods: This was a multicenter…
2022 American Transplant Congress
Use of Organ-Specific Chimeric Antigen Receptor Promotes Liver Recruitment of Regulatory T Cells
E. Landmann¹, P. Ruiz¹, A. Kurt¹, E. Kodela¹, M. Martinez-Llordella², A. Sanchez-Fueyo¹
¹King's College London, London, United Kingdom, ²Quell Therapeutics, London, United Kingdom
*Purpose: Owing to their potent immune-modulatory properties, regulatory T cells (Tregs) have been explored as novel cell therapy to induce allograft tolerance, with first clinical…
2022 American Transplant Congress
Modern Medicine Needs Modern Technology Tools
Z. S. Soltani,, S. Soltani
Ochsner Foundation Hospital, New Orleans, LA
*Purpose: Dd-cfDNA has been used as a non-invasive biomarker for allograft injury and has been shown to detect subclinical rejection with higher predictive power compare…
2022 American Transplant Congress
Older Donor Age is Associated with Worse Living Donor Liver Transplantation Outcomes in a National US Cohort
M. Kanneganti¹, K. M. Olthoff², T. Bittermann³
¹Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ²Department of Surgery, University of Pennsylvania, Philadelphia, PA, ³Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, PA
*Purpose: To evaluate the impact of increasing living donor (LD) age on living donor liver transplantation (LDLT) outcomes in the U.S.*Methods: A retrospective cohort of…
2022 American Transplant Congress
A Qualitative Comparison of Declined Hispanic and Non-Hispanic Living Liver Donor Candidates at a High-Volume Urban Transplant Center
D. Toy¹, B. Horwich¹, A. Mulgaonkar¹, A. Padilla², J. L. Dodge³, N. Kaur⁴, H. Han³
¹Department of Medicine, University of Southern California, Los Angeles, CA, ²USC Transplant Institute, University of Southern California, Los Angeles, CA, ³Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA, ⁴Department of Surgery, University of Southern California, Los Angeles, CA
*Purpose: To compare Hispanic and non-Hispanic living liver donor candidates who were declined by a multidisciplinary selection committee at a large urban transplant center.*Methods: The…
2022 American Transplant Congress
Is Remnant Liver Volume Ratio Less Than 30% Still Contraindication to Right Hepatectomy for Living Liver Donors?
J. Kim, D. Choi
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea, Republic of
*Purpose: Recently, some centers reported that extended resection with remnant/total volume ratio(RTVR) less than 30% for living donor right hepatectomy(LDRH) but there is no consensus…
2022 American Transplant Congress
Duration of Brain Death Does Not Impact Short Term Outcomes in Kidney Transplantation
A. M. Hawxby¹, R. Ketcham², J. P. Orlowski³, R. A. Squires², C. Hostetler²
¹Organ Recovery, LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK, ²LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK, ³LifeShare Transplant Donors Services, Oklahoma City, OK
*Purpose: In animal models, brain death has been shown to induce renal injury, primarily due to ischemia, inflammation, and alterations in hemodynamics. However, donor management…
2022 American Transplant Congress
Distinct Phenotypes of Kidney Transplant Recipients Aged 80 Years or Older in the United States by Machine Learning Consensus Clustering
S. A. Mao¹, C. Thongprayoon², M. A. Mao³, C. C. Jadlowiec⁴, N. Leeaphorn⁵, M. Cooper⁶, W. Cheungpasitporn²
¹Transplant Surgery, Mayo Clinic, Jacksonville, FL, ²Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL, ⁴Transplant Surgery, Mayo Clinic, Phoenix, AZ, ⁵Renal Transplant Program, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO, ⁶MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC
*Purpose: Our study aimed to cluster very elderly kidney transplant recipients aged 80 years and above using an unsupervised machine learning approach.*Methods: We performed consensus…
2022 American Transplant Congress
Cardiomyocyte Cross-Sectional Area Increases After Orthotopic Cardiac Xenotransplantation and is Not Likely a Significant Contributor to Xenograft Growth up to 9 Months
C. E. Goerlich¹, B. Griffith¹, J. Treffalls¹, P. Hanna², S. N. Hong², A. K. Singh¹, D. Ayares³, M. Mohiuddin¹
¹Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Department of Medicine, Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD, ³Revivicor, Inc., Blacksburg, VA
*Purpose: Genetically engineered (GE) pigs are thought to be an alternative organ source for patients in end-stage heart failure unable to receive a timely allograft.…
2022 American Transplant Congress
Pre-Transplant Self-Report of Length of Sobriety is Not Significantly Related to Early Return to Alcohol Use Post Transplant
J. Esswein¹, A. Powell¹, H. Bruschwein², S. Weinland¹
¹Psychiatry, VCU School of Medicine, Richmond, VA, ²The University of Virginia, Charlottesville, VA
*Purpose: Many transplant centers in the United States require six months of abstinence from alcohol prior to liver transplant. Recently, there has been an increased…