Am J Transplant, Volume 22, Suppl 3 Archives - Page 126 of 190 - ATC Abstracts

2022 American Transplant Congress
Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography
A. Feizi¹, J. R. DiRito¹, M. Harris¹, J. C. Stendahl¹, S. Spindler¹, C. M. Edwards¹, T. Lysyy¹, S. Lee¹, N. Boutagy¹, A. Fehér¹, P. Yoo¹, S. A. Hosgood², D. C. Mulligan¹, M. L. Nicholson², A. J. Sinusas¹, D. J. Haakinson¹, G. T. Tietjen¹
¹Yale School of Medicine, New Haven, CT, ²University of Cambridge, Cambridge, United Kingdom
*Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
2022 American Transplant Congress
Racial Disparities in Preemptive Kidney Transplantation Beyond Listing Estimated Glomerular Filtration Rate
K. L. King¹, S. Husain², S. Mohan²
¹Medicine - Nephrology, Columbia University Medical Center, New York, NY, ²Columbia University Medical Center, New York, NY
*Purpose: Given recent attention on the impact of the race coefficient in equations for estimated glomerular filtration rate (eGFR) on racial disparities in kidney transplantation,…
2022 American Transplant Congress
Development of a Radiomics-Based Model to Predict Graft Fibrosis in Liver Transplant Recipients: A Pilot Study
F. Qazi Arisar¹, E. Salinas-Miranda², H. Ale Ali², K. Lajkosz³, C. Chen¹, A. Azhie¹, G. M. Healy², D. Deniffel², M. A. Haider², M. Bhat¹
¹Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, ²Lunenfeld Tanenbaum Research Institute, Toronto, ON, Canada, ³Department of Biostatistics, University Health Network, Toronto, ON, Canada
*Purpose: Recurrent fibrosis complicates 40% of Liver transplants (LT), compromising long-term survival. We evaluated the ability of a model combining radiomic features on CT scans…
2022 American Transplant Congress
De Novo Donor-Specific Antibody Development with Mycophenolate versus Azathioprine in Lung Transplant Recipients
A. Prom¹, K. Walter², K. Gomez³, C. Doligalski¹, L. Lobo¹, R. Evans¹
¹UNC Health, Chapel Hill, NC, ²University of Michigan, Ann Arbor, MI, ³University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC
*Purpose: The effect of mycophenolate mofetil (MMF) or azathioprine (AZA) immunosuppression (ISN) regimens on de novo donor specific antibody (DSA) formation in lung transplant recipients…
2022 American Transplant Congress
Lack of Measles Immunity and Vaccination Rates in Patients Being Evaluated for Solid Organ Transplant: Missed Opportunities
C. Larsen¹, C. Kotton²
¹Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ²Massachusetts General Hospital, Boston, MA
*Purpose: Solid organ transplant (SOT) recipients are not eligible for live-vaccines, including the measles, mumps and rubella (MMR) vaccine, due to safety concerns on immunosuppression.…
2022 American Transplant Congress
Temporal Changes in the Peripheral Immune Profile of Acute Rejection Highlight New Mechanisms of Alloimmunity and Potential Non-Invasive Biomarkers of Rejection in Pediatric Liver Transplantation
D. N. Sarode¹, B. Rocque¹, A. Barbetta¹, P. Singh¹, C. Goldbeck¹, C. Weaver², O. Akbari¹, R. Kohli², J. Emamaullee¹
¹University of Southern California Keck School of Medicine, Los Angeles, CA, ²Children's Hospital Los Angeles, Los Angeles, CA
*Purpose: Acute rejection (AR) is common in pediatric liver transplantation (LT) and can impact late graft loss. Immune subpopulations mediating AR in LT have not…
2022 American Transplant Congress
Complement 5 Regulation Ameliorates Antibody-Mediated Rejection After Liver Transplantation in Rats
T. Tajima¹, K. Hata¹, J. Kusakabe¹, H. Miyauchi¹, X. Zhao¹, S. Kageyama¹, T. Okamoto¹, Y. Wang², E. Hatano¹
¹Dept. of HBP Surgery & Transplantation, Kyoto University, Kyoto, Japan, ²Alexion Pharmaceuticals Inc., New Haven, CT
*Purpose: Antibody-mediated rejection (AMR) is a refractory rejection after donor-specific antibody (DSA)-positive or blood-type incompatible organ transplantation. Since AMR significantly deteriorates transplant outcomes, there is…
2022 American Transplant Congress
Impact of COVID-19 on Increased Mortality in Liver Transplant Recipients in United States
K. Okumura, A. Dhand, R. Misawa, H. Sogawa, R. Bodin, D. C. Wolf, S. Nishida
Westchester Medical Center / New York Medical College, Valhalla, NY
*Purpose: COVID-19 pandemic has had a significant impact on access to routine healthcare in both hospitalized and out-patient settings. This impact was also noted in…
2022 American Transplant Congress
Gene Profiling to Distinguish Mechanisms of Liver Allograft Rejection and Acceptance in Cynomolgus Monkey
H. Sakai¹, E. Berglund¹, S. Chaudhry¹, Y. Kato¹, E. Duggan¹, J. Weiner¹, P. Alonso-Guallart¹, N. Llore¹, K. Brustle¹, J. Stern¹, B. Piegari¹, D. Ekanayake-Alper¹, M. Martinez², G. Pierre¹, M. Danton¹, S. Kofman¹, D. Ordanes¹, D. Hajosi¹, J. Lefkowitch³, A. Iuga¹, T. Kato⁴, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Departments of Pathology and Cell Biology, Columbia University, New York, NY, ⁴Department of Surgery, Columbia University, New York, NY
*Purpose: Liver is an immune regulatory organ. Spontaneous resolutions from rejection have been seen in our orthotopic cynomolgus monkey liver transplant models for tolerance induction…
2022 American Transplant Congress
Laparoscopic Kidney Transplantation : A Lost Art ?
F. J. Osella¹, I. Cabrera¹, J. Walther², L. Leon², O. Guardia², M. Rial²
¹Surgery - Kidney and Pancreas Trasplant, ITAC by Diaverum, Buenos Aires, Argentina, ²Nephrology, ITAC by Diaverum, Buenos Aires, Argentina
*Purpose: Laparoscopic surgery and currently robot-assisted surgery have transformed the current surgery paradigm, showing a lower systemic inflammatory response, less post-operative pain, smaller incisions, shorter…