Am J Transplant, Volume 22, Suppl 3 Archives - Page 122 of 190 - ATC Abstracts

2022 American Transplant Congress
Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee
L. Danziger-Isakov¹, J. D. Goldman¹, A. Wooley¹, S. Pouch¹, A. Agarwal¹, G. Berry¹, K. Dunn¹, S. Ho¹, M. Kittleson¹, D. H. Lee¹, D. Levine¹, C. Marboe¹, G. Marklin¹, R. Razonable¹, S. Taimur¹, H. Te¹, C. Fox², C. Jett², S. Booker², D. Klassen², R. LaHoz¹
¹OPTN, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
2022 American Transplant Congress
Avoiding Cytomegalovirus Mismatching in Deceased Donor Kidney Allocation System in the US
B. Tanriover¹, B. Sandikci², Y. Ulukus³, M. A. Ergun², V. K. Ariyamuthu¹, M. Al-Obaidi⁴, T. Zangeneh⁴
¹Division of Nephrology, The University of Arizona, Tucson, AZ, ²Department of Industrial Engineering, Istanbul Technical University, Istanbul, Turkey, ³Department of industrial Engineering, Istanbul Technical University, Istanbul, Turkey, ⁴Division of Infectious Disease, The University of Arizona, Tucson, AZ
*Purpose: Cytomegalovirus (CMV) mismatch, donor-positive/recipient-negative serostatus (D+/R-), carries a high risk of developing CMV infection, graft failure mortality. The current kidney allocation system (KAS) does…
2022 American Transplant Congress
Cardiac Catheterization in ESKD Patients with High Cardiovascular Risk Prior to Kidney Transplantation
L. Morena¹, A. Al Jurdi², M. S. Bittencourt³, A. C. Bucay², N. Elias¹, R. Palsson², L. V. Riella¹
¹Transplant Surgery, Massachusetts General Hospital - Harvard Medical School, Boston, MA, ²Transplant Nephrology, Massachusetts General Hospital - Harvard Medical School, Boston, MA, ³Cardiac Imaging, Cardiology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Cardiovascular disease is the leading cause of death after kidney transplantation (KT), with a high risk of myocardial infarction (MI) in the peri-transplantation period.…
2022 American Transplant Congress
Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients
S. Frey, J. Ruck, J. Alejo, L. Barker, W. Werbel, R. Avery, D. Segev, P. Shah
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…
2022 American Transplant Congress
Tabelecleucel (Tab-cel) for Solid Organ (SOT) or Allogeneic Hematopoietic Cell Transplant (HCT) Recipients with Epstein-Barr Virus-Driven Post Transplant Lymphoproliferative Disease (EBV⁺ PTLD) After Failure Of Rituximab (R) ± Chemotherapy (CT) (ALLELE)
S. Prockop¹, A. Beitinjaneh², S. Choquet³, S. Dahiya⁴, R. Dinavahi⁵, R. Farah⁶, L. Gamelin⁵, A. Joshi⁵, A. Mehta⁵, P. Nayak⁵, R. Reshef⁷, G. Satyanarayana⁸, P. Stiff⁹, W. Ye⁵, K. M. Mahadeo¹⁰
¹Boston Children's Hospital/Dana Farber Cancer Institute, Boston, MA, ²University of Miami/Jackson Memorial Hospital, Miami, FL, ³Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France, ⁴University of Maryland School of Medicine, Baltimore, MD, ⁵Atara Biotherapeutics, South San Francisco, CA, ⁶UPMC Hillman Cancer Center, Pittsburgh, PA, ⁷Columbia University Medical Center, NY, NY, ⁸Ingram Cancer Center, Vanderbilt Health, Nashville, TN, ⁹Loyola University Medical Center, Chicago, IL, ¹⁰MD Anderson Cancer Center, Houston, TX
*Purpose: Tab-cel is an investigational, off-the-shelf, allogeneic EBV-specific T-cell immunotherapy for serious EBV-driven diseases, including EBV+ PTLD. Poor overall survival (OS) in patients (pts) with…
2022 American Transplant Congress
Race Inequity in Liver Transplant Waitlisting: Effect Modification by Psychosocial Factors and the Stanford Integrated Psychosocial Assessment for Transplant
S. Deutsch-Link¹, L. Nephew², E. Weinberg³, R. Weinrieb⁴, M. Serper³
¹Gastroenterology & Hepatology, University of North Carolina, Chapel Hill, NC, ²Gastroenterology & Hepatology, Indiana University, Chapel Hill, NC, ³Gastroenterology & Hepatology, University of Pennsylvania, Philadelphia, PA, ⁴Psychiatry, University of Pennsylvania, Philadelphia, PA
*Purpose: Race inequity in liver transplantation (LT) has been a longstanding area of injustice within the field of hepatology. Information from psychosocial evaluations and The…
2022 American Transplant Congress
Fibroblastic Reticular Cell Subset Transcriptional Reprogramming Differs in Response to Immunity versus Tolerance
L. Li¹, Y. Song¹, M. Shirkey¹, A. Kensiski¹, W. Piao¹, V. Saxena¹, S. Gavzy¹, B. Ma¹, R. Abdi², J. Bromberg¹
¹UMB, Baltimore, MD, ²Harvard University, Boston, MD
*Purpose: Lymph node (LN) fibroblastic reticular cells (FRCs) are central contributors to the LN niche. We hypothesized that FRC subsets reactive to immunity versus tolerance…
2022 American Transplant Congress
Validation of a Hypertension Risk Calculator for Living Kidney Donors
E. S. Helgeson¹, S. Vempati¹, E. F. Palzer¹, G. Mjøen², A. J. Haugen³, A. Matas⁴
¹Division of Biostatistics, University of Minnesota, Minneapolis, MN, ²Department of Transplant Medicine, Oslo University Hospital, Oslo, Norway, ³Department of Internal Medicine, Bærum Hospital, Sandvika, Norway, ⁴Department of Surgery, University of Minnesota, Minneapolis, MN
*Purpose: It would be ideal if candidates considering kidney donation understood their long-term risks. Using single-center data (n=4055; median [IQR] f/u: 18 [9-28] yrs), we…
2022 American Transplant Congress
Digital Spatial Profiling of Kidney Allograft Biopsies with Chronic Allograft Dysfunction in African American Transplant Recipients
C. R. Dorr¹, S. A. Elmer¹, B. Wu², B. Guo², J. Czyzyk², G. Crary³, G. Onyeaghala¹, W. Oetting², P. Jacobson², R. B. Mannon⁴, G. Agarwal⁵, J. Maltzman⁶, A. Matas², A. Israni³
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³Hennepin County Medical Center, Minneapolis, MN, ⁴Medicine, University of Nebraska Medical Center, Omaha, NE, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶Stanford University, Palo Alto, CA
*Purpose: Understanding tissue heterogeneity is important to identify the molecular and cellular mechanisms of kidney allograft loss in African American (AA) transplant recipients. Our aim…
2022 American Transplant Congress
Higher Baseline Serum Creatinine Levels AreAssociated with an Increased Incidence of Renal Replacement Therapy in Patients with Hepatorenal Syndrome Type 1 on the Liver Transplant Waitlist
S. N. Sclair¹, A. Befeler², K. Jamil³
¹Hepatology, University Hospitals Cleveland Medical Center & Case Western Reserve University, Cleveland, OH, ²Gastroenterology, Hepatology, Transplant Hepatology, Saint Louis University School of Medicine, St Louis, MO, ³Hepatology, Mallinckrodt Pharmaceuticals, Clinton, NJ
*Purpose: Pretransplant and posttransplant renal replacement therapy (RRT) is associated with increased morbidity and mortality in liver transplant recipients, including those with Hepatorenal syndrome type…