ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    High TTV Load Before First Vaccine Dose is Associated with Poor Serological Response to Covid-19 Vaccination in Lung Transplant Recipients

    C. C. Van Leer Buter1, R. A. Hoek2, E. A. Verschuuren3, R. D. de Vries4, D. van Baarle1, M. van der Heiden1, H. G. Niesters1, C. GeurtsvanKessel4

    1Dept. of Medical Microbiology, University Medical Center Groningen, Groningen, Netherlands, 2Dept. of Pulmonary Medicine, Erasmus Medical Center, Rotterdam, Netherlands, 3Dept. of Pulmonary Diseases,, University Medical Center Groningen, Groningen, Netherlands, 4Dept. of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: Torque tenovirus (TTV), a highly prevalent virus which is not known to cause pathology in humans, is currently being investigated as a marker of…
  • 2022 American Transplant Congress

    Analysis of Sars-Cov-2-Specific T-Cell Responses Using Novel Single-Cell Multiplexed Isolight in Covid-19 Convalescents

    Y. Sambandam1, J. He1, N. Vanderhyde2, L. Gallon1, J. Leventhal1, J. Mathew1

    1Northwestern University, Chicago, IL, 2IsoPlexis, Branford, CT

    *Purpose: COVID-19 has poor outcomes in transplant recipients with reduced antibody responses. However, the exact cellular immune response against SARS-CoV-2 remains largely unclear. We developed…
  • 2022 American Transplant Congress

    Barriers to Completing the Transplant Evaluation Process: A Mixed-Methods Study

    E. J. Gordon1, J. J. Uriarte1, A. N. McLagan1, B. Kuramitsu1, J. Gacki-Smith1, M. Shumate2, L. McElroy3, J. Caicedo1

    1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Northwestern University, Evanston, IL, 3Duke University, Durham, NC

    *Purpose: Little is known about patient-reported factors affecting patients’ access to the kidney transplant waitlist after starting evaluation. We qualitatively assessed patients’ perceived barriers to…
  • 2022 American Transplant Congress

    COVID Infection Among Kidney Transplant Recipient During the Era of COVID Vaccination: Management Outcomes

    G. Uehara, K. Soliman, V. Rao, M. Casey, D. Taber, M. Posadas Salas

    Nephrology, Medical University of South Carolina, Charleston, SC

    *Purpose: COVID pandemic has posed a significant challenge among kidney transplant recipients (KTR) due to their immunocompromised state. There is uncertainty on immunosuppression (IS) management…
  • 2022 American Transplant Congress

    Safety and Immunogenicity of BNT-162b2 versus Chadox1 Vaccine in Solid Organ Transplant Recipients: Prospective Study

    A. Ajlan1, T. Ali2, H. Aleid2, K. Almeshari2, M. Alkaff3, S. Althuwaidi4, L. Fajji2, A. Alali5, D. Halabi6, A. Ullah7, K. H. Marquez8, B. Elmikkaoui9, A. Alrajhi10, A. Zidan11, E. Albogumi.12, K. Bzeizi13, R. Almaghrabi14, E. DeVol15, M. Al-Awwami,16, S. Alghamdi13, P. Broering2

    1Pharmaceutical Care Division - Organ Transplant Centre of Excellence, King Faisal Specialist Hospital and Research Centre (KFSHRC), Riaydh, Saudi Arabia, 2Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 3Medical Laboratory, KFSHRC, Riaydh, Saudi Arabia, 4Medical Microbiology, KFSHRC, Riaydh, Saudi Arabia, 5Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 6Transplant Coordination Team - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 7Kidney & Pancreas Health Centre, KFSHRC, Riaydh, Saudi Arabia, 8Analytics Data Centre - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 9Data Management - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 10Infectious Diseases - Medicine Department, KFSHRC, Riaydh, Saudi Arabia, 11Abdominal Transplant & Hepatobiliary Surgery Centre, KFSHRC, Riaydh, Saudi Arabia, 12Data Management. - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 13Liver & Small Bowel Health Centre, KFSHRC, Riaydh, Saudi Arabia, 14Infectious Diseases - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia, 15Biostatistics, Epidemiology &Scientific Computing, KFSHRC, Riaydh, Saudi Arabia, 16Histocompatibility and Immunogenetics Laboratory Kidney & Pa - Organ Transplant Centre of Excellence, KFSHRC, Riaydh, Saudi Arabia

    *Purpose: Data showed seroconversion after different SARS-CoV-2 vaccination platforms might yield diminished response in transplant recipients. However, it is unknown whether different vaccination platforms could…
  • 2022 American Transplant Congress

    Viral-Specific Cytotoxic T-Cell Responses in Hla-Sensitized Kidney Transplant Patients Maintained on Everolimus and Low Dose Tacrolimus

    R. Zhang1, S. Ge1, M. Chu1, J. Kahwaji2, A. Karasyov1, D. Lovato1, A. Vo2, J. Choi2, M. Toyoda1, S. Jordan2

    1Transplant Immunology Laboratory, Cedars Sinai Medical Center, Los Angeles, CA, 2Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: Post-transplant immunosuppression with “everolimus + reduced dose tacrolimus” (Ev + Taclow) is reported to reduce the risk of viral infections compared to standard doses…
  • 2022 American Transplant Congress

    Outcomes in Renal Transplant Recipients Receiving Pre-Transplant Financial Assistance Through the American Kidney Fund

    H. Roppo1, P. Klem1, B. Crowther1, E. Sartain1, K. Schoeppler1, P. T. Kennealey2, B. Kaplan3

    1Department of Pharmacy, University of Colorado Hospital, Aurora, CO, 2Department of Surgery, University of Colorado Hospital, Aurora, CO, 3Department of Renal Med Diseases/Hypertension, University of Colorado Hospital, Aurora, CO

    *Purpose: Pre-transplant financial assistance for insurance premiums is available for eligible patients through the American Kidney Fund (AKF), but this funding ends within the first…
  • 2022 American Transplant Congress

    Characterization of Activated Islet Proliferating Cells (AIPCs) During Maturation to Pseudo-Islets

    Y. Garciafigueroa, J. B. Pollett, N. Thai, R. Bottino

    Imagine Pharma, Pittsburgh, PA

    *Purpose: We have previously described a novel population of cells developed from human islets called AIPCs (Activated Islet Proliferating Cells). AIPCs co-express CD133, glucagon and…
  • 2022 American Transplant Congress

    Kidney Transplant Recipients with Diabetic Mellitus Demand Larger Doses of Mycophenolate Mofetil

    D. Takamoto, H. Sasaki, S. Harada, Y. Takada, H. Harada, T. Tsujimoto

    Kidney transplant surgery and Urology, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: To monitor blood concentration of immunosuppressants, therapeutic drug monitoring (TDM) is required at any point after kidney transplantation (KT) to prevent kidney graft from…
  • 2022 American Transplant Congress

    Results of a Pilot Adherence Activity for Pharmacy Learners on a Solid Organ Transplant Service

    J. Zumbrunnen

    Pharmacy, Emory University Hospital, Atlanta, GA

    *Purpose: The purpose was to determine if the ability of pharmacy learners to educate patients and help overcome barriers to medication adherence is improved after…
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