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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Use of Viral Specific T Cell Therapy in Solid Organ Transplant Recipients – A Single Center Experience

    G. McGraw1, N. Patel2, K. Patel1, S. Bumb3, A. Govil4, M. Anand1

    1University of Cincinnati, Cincinnati, OH, 2Nephrology, University of Cincinnati, Cincinnati, OH, 3Nephrology, Internal Medicine, University of Cincinnati Medical Center, Blue Ash, OH, 4Univ of Cincinnati, Cincinnati, OH

    *Purpose: Viral infections such as BK virus (BKV), cytomegalovirus (CMV) and adenovirus after kidney transplantation negatively impact outcomes in solid organ transplant (SOT) recipients despite…
  • 2022 American Transplant Congress

    A Novel, High Throughput Droplet Digital PCR-Based Indel Quantification Method for the Detection of Circulating Donor-Derived Cell-Free DNA After Kidney Transplantation

    J. G. Verhoeven1, K. Boer1, A. M. Peeters1, M. C. Clahsen-van Groningen2, J. I. Roodnat1, J. van de Wetering1, D. Nieboer3, D. A. Bost4, C. C. Baan1, D. A. Hesselink1

    1Department of Internal Medicine, Erasmus MC Transplant Institute, Rotterdam, Netherlands, 2Department of Pathology, University Medical Center Rotterdam, Rotterdam, Netherlands, 3Department of Public Health, University Medical Center Rotterdam, Rotterdam, Netherlands, 4JETA Molecular, Utrecht, Netherlands

    *Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising minimally invasive biomarker for acute rejection (AR) in kidney transplant recipients. To assess the diagnostic value of…
  • 2022 American Transplant Congress

    Peripheral Blood Immune Cell Profiles of Corneal Transplant with and without Acute Rejection

    J. Hjortdal1, M. Griffin2, C. C. Murphy3, S. Brouard4, N. Degauque4

    1Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark, 2National University of Ireland, Galway, Galway, Ireland, 3Royal Victoria Eye and Ear Hospital, Dublin, Ireland, 4Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, Nantes, France

    *Purpose: Acute rejection (AR) of allogeneic corneal transplantation (CT) has a profound effect on subsequent graft survival, indicating that immunological damage is often not fully…
  • 2022 American Transplant Congress

    Impact of Sars-CoV-2 Vaccination on Donor-Derived Cell Free DNA Levels in Renal Transplant Recipients

    H. Alvarado Verduzco, E. Daniel, D. Kim, A. Hussain, S. Mohan, D. Cohen

    Columbia University Irving Medical Center, New York, NY

    *Purpose: COVID-19 poses a disproportionate threat to renal transplant recipients (RTR), who are chronically immunosuppressed. Studies have indicated a 16% mortality rate compared to
  • 2022 American Transplant Congress

    Detection of Early Graft Injury After Liver Transplantation with Blood-Bile Ratio of Tacrolimus: The TUBE Trial

    M. M. Pascale1, G. Bianco1, L. Ferri1, F. Giovinazzo1, A. Liguori2, G. Marrone2, A. Grieco2, S. Agnes1

    1General Surgery and Liver Transplant Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy, 2Transplant Hepatology Unit, Fondazione IRCSS - Policlinico "A. Gemelli", Roma, Italy

    *Purpose: The aim of the“Tacrolimus in Bile”(TUBE)Trial is the creation of a laboratory parameter for the early detection of hepatic injury after liver transplant.*Methods: TUBE…
  • 2022 American Transplant Congress

    Steatosis Following Liver Transplantation for Nonalcoholic Steatohepatitis is Associated with a Higher Rate of Cardiovascular Complications

    W. Alhamoudi1, S. Alqahtani2, K. Bzeizi2, A. Albenmousa2, Y. Saleh2, D. Broering2, S. Alghamdi2

    1Medicine, King Saud University, Riyadh, Saudi Arabia, 2Liver Transplantation, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

    *Purpose: Cirrhosis secondary to Nonalcoholic Steatohepatitis (NASH) is projected to become the leading indication for liver transplantation (LT) worldwide. Objectives: to evaluate the prevalence of…
  • 2022 American Transplant Congress

    Retransplantation in a High-Volume Institution: Historical, Socioeconomic and Survival Trends

    D. von Ahrens, O. Sulimani, M. Holzner, M. Akhtar, S. Florman, A. Arvelakis

    The Mount Sinai Hospital, New York, NY

    *Purpose: Retransplantation for liver allograft failure is a challenge within the field. The evolution of organ allocation policy from Child to MELD in 2002 and…
  • 2022 American Transplant Congress

    Safety and Efficacy of Early Central Line Removal in Post Liver Transplant Patients

    T. Shamaa1, E. MacLean1, O. Shamaa2, Z. Lu1, A. Hinge3, S. Saymuah3, A. Mohamed4, T. Kitajima4, S. Nagai4, M. Rizzari4, A. Yoshida4, M. Abouljoud4, K. Collins4

    1General Surgery, Henry Ford Hospital, Detroit, MI, 2Internal Medicine, Henry Ford Hospital, Detroit, MI, 3Wayne State University School of Medicine, Detroit, MI, 4Henry Ford Transplant Institute, Detroit, MI

    *Purpose: Avoiding central line-associated infections (CLABSIs) is paramount in liver transplant recipients. As a hospital-wide infection control initiative at our institution, early removal of central…
  • 2022 American Transplant Congress

    Impact of Donor-to-Recipient Body Surface Area Ratio on Graft Survival and Mortality Following Deceased Donor Liver Transplants

    S. Radomski, L. Zeiser, A. Massie, S. Ottmann, D. Segev, E. King

    Surgery, Johns Hopkins University, Baltimore, MD

    *Purpose: The impact of size mismatch on graft survival in living donor liver transplant is well established but is not a common concern in deceased…
  • 2022 American Transplant Congress

    National Landscape of the Utilization of Living Donor Liver Allografts in Redo Liver Transplantation

    J. I. López, K. Nijhar, J. Mitchell, L. Bowles Zeiser, K. Key, A. Asamoah-Mensah, A. Thomas, R. Haneda, S. K. Romano, J. Huang, A. Massie, A. M. Cameron, D. L. Segev, E. A. King

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: To examine the use of living donor liver allografts in patient’s requiring redo liver transplantation.*Methods: Using data from SRTR 2009-2020, we evaluated the number…
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