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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pediatric Kidney Transplant Delays Due To Respiratory Viruses: A Provider Survey

    T. A. Heald-Sargent1, S. Manz2, T. Barton3, P. Verghese4

    1Pediatric Infectious Diseases, Lurie Children's Hospital/Northwestern University, Chicago, IL, 2Central Michigan University, Mount Pleasant, MI, 3Pediatric Infectious Diseases, UT Health San Antonoio, San Antonio, TX, 4Pediatric Nephrology, Lurie Children's Hospital/Northwestern University, Chicago, IL

    *Purpose: This study aimed to characterize the management and impact of respiratory viral infections on pediatric kidney transplantation waitlisted candidates.*Methods: An IRB-approved, anonymous REDCap survey…
  • 2022 American Transplant Congress

    Changes in Cold Ischemia Time and Transplantation Practices with the Concentric Model of Kidney Allocation

    C. M. Puttarajappa1, P. Sood1, A. Tevar1, V. Gunabushanam1, S. Hariharan1, S. Mohan2

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2Columbia University, New York, NY

    *Purpose: Evaluate impact of the new concentric kidney allocation system (KAS250) on kidney utilization, allocation practices and cold ischemia time (CIT).*Methods: Using data from the…
  • 2022 American Transplant Congress

    Validation of the PROMIS® Medication Adherence Scale Among Kidney Transplant Recipients on Tacrolimus

    J. D. Peipert1, R. Slay2, B. Smith2, D. Cella1, A. Keys2, D. Taber2

    1Northwestern University, Chicago, IL, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Kidney transplant recipients (KTR) take a daily regimen of immunosuppression medication that almost inevitably includes tacrolimus (TAC). Non-adherence to TAC is a strong predictor…
  • 2022 American Transplant Congress

    Differentially Methylated Genes Predict Post-Transplant Relapse of Unresectable Hepatoblastoma

    M. Ningappa1, M. Muarya2, C. Ashokkumar1, H. Hakonarson3, S. Subramaniam4, R. Sindhi1

    1Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Department of Bioengineering & San Diego Supercomputer Center, University of California, San Diego, CA, 3Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, 4Department of Computer Science and Engineering, and Nanoengineering, University of California, San Diego, La Jolla, CA

    *Purpose: Hepatoblastoma (HB), a developmental liver tumor of childhood requires liver transplantation (LT) if it remains unresectable despite chemotherapy. Post-transplant relapse in up to 20%…
  • 2022 American Transplant Congress

    Cmv-Specific Cell-Mediated Immune Reconstitution in High-Risk Hematopoietic Cell Transplant Recipients Receiving Letermovir Prophylaxis

    M. Z. Abidi1, K. Garth1, J. Gutman2, A. Weinberg1

    1Medicine, Infectious Disease, University of Colorado, Aurora, CO, 2Medicine, Hematology and Oncology, University of Colorado, Aurora, CO

    *Purpose: In the absence of antiviral prophylaxis following Hematopoietic Cell Transplant (HCT), the incidence of clinically significant cytomegalovirus reactivation (cCMV) is 30% in CMV seropositive…
  • 2022 American Transplant Congress

    Social Determinants of Health Impact Successful Listing for Liver and Kidney Transplant

    J. B. Henson, D. Mohottige, J. M. Wilder, A. J. Muir, L. M. McElroy

    Duke University, Durham, NC

    *Purpose: To evaluate the association between community socioeconomic disadvantage and structural social determinants of health (SDOH) on successful listing for liver (LT) and kidney transplantation…
  • 2022 American Transplant Congress

    Presence of Infiltrating Regulatory T Cells in the Cardiac Xenografts and Their Potential Role in Graft Survival

    A. K. Singh1, C. E. Goerlich1, G. Braileanu1, A. Hershfeld1, T. Zhang1, I. Tatarov1, B. Lewis1, F. Sentz1, D. Ayares2, B. Griffith1, M. M. Mohiuddin1

    1Department of Surgery, University of Maryland School of Medicine, Baltimore, MD, 2Revivicor Inc, Blacksburg, WV

    *Purpose: Regulatory T (CD4+CD25HiFoxP3+) cells (Treg) are a very small subset of CD4+ T cells that have been shown to play an important role in…
  • 2022 American Transplant Congress

    Early Clinical Experience With Nirmatrelvir/ritonavir For Treatment Of Covid-19 In Solid Organ Transplant Recipients

    D. Salerno1, D. Jennings2, N. Lange3, D. Kovac1, T. Shertel1, J. Chen4, J. Hedvat5, J. Scheffert1, R. S. Brown6, M. Pereira7

    1NewYork-Presbyterian Hospital, New York, NY, 2Long Island University, Brooklyn, NY, 3Pharmacy, NewYork-Presbyterian Hospital, New York, NY, 4Columbia University Irving Medical Center, Fort Lee, NJ, 5New York Presbyterian Hospital, Tenafly, NJ, 6Weill Cornell Medicine, New York, NY, 7New York Presbyterian Hospital, New York, NY

    *Purpose: Nirmatrelvir/ritonavir use has not yet been described in solid organ transplant recipients (SOTR) who become infected with COVID-19. The objective of our study was…
  • 2022 American Transplant Congress

    Non-HLA Antibodies to G Protein-Coupled Receptors and Allograft Survival in Pediatric Kidney Transplant Recipients: Short- and Long-Term Outcomes

    M. Pearl1, L. Chen1, P. Weng1, E. T. Chambers2, E. F. Reed3

    1UCLA, Los Angeles, CA, 2Pediatrics, Duke University, Durham, NC, 3Univ of California LA, Los Angeles, CA

    *Purpose: We have recently shown that the non-HLA antibodies to angiotensin II type 1 receptor (AT1R-Ab) and endothelin-1 type A receptor (ETAR-Ab) are prevalent and…
  • 2022 American Transplant Congress

    Kidney Transplant Alone Recipients with Advanced Liver Disease Have Similar Outcomes to Those without Advanced Liver Disease

    R. R. Nathani, S. M. Rutledge, C. Villarroel, R. Shapiro, G. Y. Im

    Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: The prevalence of concomitant liver disease (CLD) in patients with ESRD is reported to be 7-40%. Safety of kidney transplant alone (KTA) in those…
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