Am J Transplant, Volume 22, Suppl 3 Archives - Page 119 of 190 - ATC Abstracts

2022 American Transplant Congress
Left Digit Bias in Selection and Acceptance of Deceased Donor Organs
C. E. Jacobson¹, C. S. Brown², K. H. Sheetz³, S. A. Waits²
¹University of Michigan Medical School, Ann Arbor, MI, ²Department of Surgery, University of Michigan, Ann Arbor, MI, ³Department of Surgery, University of California San Francisco, San Francisco, CA
*Purpose: Organs suitable for donation are a scarce resource and maximizing the use of available donor organs is a public health priority. Transplantable organs may…
2022 American Transplant Congress
A FRET-Based Technique to Quantify Foxp3 Acetylation in T_REG
F. F. Gonzalez¹, G. Vilanova², M. Fribourg¹
¹Icahn School of Medicine at Mount Sinai, New York, NY, ²Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona, Spain
*Purpose: Foxp3 acetylation is essential to TREG stability and function. Acetylation protects Foxp3 from degradation, and acetylated Foxp3 translocates to the nucleus to activate the…
2022 American Transplant Congress
Single Port Robotic Extraperitoneal Kidney Transplantation: Technical Aspects
A. Kaviani, J. Kaouk, M. Abou Zeinab, A. Beksac, E. Ferguson, Y. Lin, D. Goldfarb, A. Wee, M. Eltemamy
Cleveland Clinic, Cleveland, OH
*Purpose: To provide, in a video format, tips and tricks for surgical steps of the single-port robotic extraperitoneal kidney transplantation.*Methods: Thirteen patients underwent single-port robotic…
2022 American Transplant Congress
PFIC- Outcome and Time to Transplant After Biliary Diversion According to Genetic Subtypes
M. Schulze¹, A. Sahloul², E. Lainka³
¹Organ Transplant Centre of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia, ²Department of General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany, ³Department of Pediatric Gastroenterology, University Hospital Essen, Essen, Germany
*Purpose: Progressive familial intrahepatic Cholestasis (PFIC) is a heterogeneous autosomal recessive disease characterized by progressive cholestasis, pruritus leading to liver injury. Surgical therapy aims in…
2022 American Transplant Congress
A Physical Therapy and Nutritional Intervention to Improve Frailty in the Liver Transplant Candidate
N. Bartell¹, K. Dokus², K. Helbig¹, J. Martens², B. Al-Judaibi¹
¹University of Rochester, Rochester, NY, ²Univeristy of Rochester, Rochester, NY
*Purpose: Sarcopenia and frailty are independent predictors of mortality in cirrhotic patients; increased access to physical therapy (PT) and registered dietician (RD) services have the…
2022 American Transplant Congress
Daratumumab for Recurrence of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits in a Post-Kidney Transplant Recipient: A Case Report
K. Progar¹, T. Alhamad², H. Murad³, A. Java⁴, A. Malone⁵, J. Gaut⁶, R. Delos Santos⁷, M. Merzkani⁸
¹Transplant, Barnes-Jewish Hospital, St. Louis, MO, ²Washington University School of Medicine at St. Louis, Saint Louis, MO, ³Transplant, Washington University, St. Louis, MO, ⁴Washington University School of Medicine in St. Louis, Saint Louis, MO, ⁵Washington University School of Medicine, Saint Louis, MO, ⁶Washington University, Saint Louis, MO, ⁷Transplant Nephrology, Washington University School of Medicine, St. Louis, MO, ⁸Transplant, Washington University School of Medicine, Saint Louis, MO
*Purpose: Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits (PGNMID) is a rare kidney disease associated with a high rate of recurrence post-kidney transplantation resulting in graft…
2022 American Transplant Congress
Identification of Soluble and Cellular Biomarkers in Blood of End-Stage Patients Before Pediatric Liver Transplantation (pLTx)
E. Chichelnitskiy¹, L. Ruhl², I. Goldschmidt³, A. Karch⁴, L. Antiga⁵, D. Debray⁶, L. Hierro⁷, D. Kelly⁸, V. McLin⁹, E. Nicastro⁵, J. Pawlowska¹⁰, R. Mikolajczyk¹¹, U. Baumann¹², C. Falk¹³
¹Institute of Transplant Immunology, Hannover Medical School (MHH), Hannover, Germany, ²Institute of Transplant Immunology, MHH, Hannover, Germany, ³Division of Pediatric Gastroenterology and Hepatology, MHH; European Paediatric Liver Transplantation Network, Hannover, Germany, ⁴Research Group Epidemiological and Statistical Methods, Helmholtz Centre for Infection Research, Braunschweig; German Center for Infection Research, TTU-IICH Hannover; Institute for Epidemiology and Social Medicine, University of Münster, Münster, Germany, ⁵Ospedali Riuniti di Bergamo, Bergamo, Italy, ⁶Hôpital Necker-Enfants Malades, Paris, France, ⁷Hospital Infantil Universitario La Paz, Madrid, Spain, ⁸Birmingham Children's Hospital, Birmingham, United Kingdom, ⁹Service Spécialités Pédiatriques, Genève, Switzerland, ¹⁰Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children’s Memorial Health Institute, Warsaw, Poland, ¹¹German Center for Infection Research, TTU-IICH Hannover; Institute of Medical Epidemiology, Biostatistics and Medical Informatics, University of Halle, Halle, Germany, ¹²Division of Pediatric Gastroenterology and Hepatology, MHH; Birmingham Children’s Hospital, UK; European Paediatric Liver Transplantation Network, Hannover, Germany, ¹³Institute of Transplant Immunology, MHH; German Center for Infection Research, TTU-IICH, Hannover, Germany
*Purpose: In the European multicentre “ChilSFree” study we aimed to identify soluble and cellular biomarkers in blood of various end-stage diseases before pLTx.*Methods: Using flow…
2022 American Transplant Congress
Alloprimed Antibody-Suppressor CD8⁺ TCells Preferentially Kill Alloprimed Germinal Center B Cells
J. Zimmerer, S. Chaudhari, G. Bumgardner
OSUWMC, Columbus, OH
*Purpose: Antibody-mediated rejection (AMR) is a significant contributor to transplant rejection. Our prior work identified a novel subset of CXCR5+CD8+ T cells (CD8+ TAb-supp cells)…
2022 American Transplant Congress
Single Cell RNAseq Analysis of Human Renal Allograft Rejection Demonstrates Distinct Transcriptomic Profiles That Vary Based on the Type of Maintenance Immunosuppression
T. Shi¹, A. Burg¹, K. Roskin², J. Rush³, B. Haraldsson³, A. Shields⁴, R. Alloway⁴, E. Woodle⁵, D. Hildeman¹
¹Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Novartis Pharmaceuticals AG, Basel, Switzerland, ⁴Internal Medicine, University of Cincinnati, Cincinnati, OH, ⁵Surgery, University of Cincinnati, Cincinnati, OH
*Purpose: Rejection therapy has remained unchanged for 60 years and is associated with significant failure and infection rates. Development of new anti-rejection therapies requires mechanistic…
2022 American Transplant Congress
Portal Vein Challenges in Pediatric Liver Transplantation: The Utility of Interposition Grafts as an Acceptable Management Strategy
K. Etesami¹, R. Hogen², J. Cervantes³, Y. Kwon⁴, S. Zielsdorf³, J. Emamaullee³, Y. Genyk³
¹Surgery, Children's Hospital Los Angeles, Los Angeles, CA, ²University of Southern California, West Hollywood, CA, ³University of Southern California, Los Angeles, CA, ⁴Hepatobiliary and Abdominal Transplant Surgery, University of Southern California, Los Angeles, CA
*Purpose: Portal vein (PV) anomalies and portal vein thrombosis (PVT) can present as challenging cases in the pediatric cohort, necessitating analysis and an algorithmic approach.*Methods:…