ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Possible Recurrence Must Not Limit Kidney Transplantations for Patients with Focal Segmental Glomerulosclerosis

    A. Angeletti, M. Gentile, G. Ghiggeri, M. Bruschi, F. Lugani, G. Caridi

    Istituto Giannina Gaslini, Genova, Italy

    *Purpose: Non-genetic forms of Focal Segmental Glomerulosclerosis (FSGS) are at high risk of recurrence after kidney transplant (KT) (55%), when compared to inherited forms (0-4%)…
  • 2022 American Transplant Congress

    Normothermic Machine Perfusion (NMP) Improves Access to Transplantation for Late Liver Re-Transplant Candidates

    D. Sneiders1, H. Lembach1, A. Hann1, A. Nutu1, J. Hodson1, J. Isaac1, R. Taylor2, M. Armstrong1, T. Perera1, H. Hermien1

    1Queen Elizabeth Hospital, Birmingham, United Kingdom, 2NHS Blood and Transplant, bristol, United Kingdom

    *Purpose: Late liver re-transplantation (LLrT) is a complex surgical procedure. Candidates for LLrT spend longer on the waitlist than primary transplant candidates due to selectivity…
  • 2022 American Transplant Congress

    Tacrolimus and Mycophenolic Acid Therapeutic Exposure Targets in Black and White Kidney Transplant Recipients

    K. Tornatore1, K. Attwood1, S. Chang1, A. Gundroo2, B. Murray1

    1Univeristy at Buffalo/SUNY, Buffalo, NY, 2Ohio State Medical Center, Columbus, OH

    *Purpose: Tacrolimus and Mycophenolic Acid(MPA), the preferred immunosuppressive regimen for kidney transplant recipients(KTR), exhibit interpatient pharmacokinetic variability which may impact allograft survival in Black and…
  • 2022 American Transplant Congress

    Longitudinal Characterization of the Microvirome in a Cohort of Renal Transplant Recipients

    A. C. Johnson, G. Karadkhele, C. P. Larsen

    Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections, with different immunosuppression regimens resulting in…
  • 2022 American Transplant Congress

    Urinary Cell CTOT-04 Signature is Diagnostic of Glomerulitis in Kidney Allograft Biopsies

    T. Salinas1, C. Li1, C. Snopkowski1, K. Chen1, S. Albakry1, S. Salvatore2, S. Seshan2, J. R. Lee1, M. Thangamani1, D. Dadhania1, M. Suthanthiran1

    1Nephrology, Weill Cornell-NYPH, New York, NY, 2Pathology, Weill Cornell-NYPH, New York, NY

    *Purpose: Antibody mediated rejection is a significant complication after kidney transplantation and is an important cause of allograft failure. In the multicenter CTOT-04 study, we…
  • 2022 American Transplant Congress

    TNX-1500, an Fc-Modified Anti-cd154 Antibody, Prolongs Nonhuman Primate Cardiac Allograft Survival

    S. Miura1, Z. Abady1, F. Pollok1, M. Ma1, K. Kinoshita1, S. Fogarty2, P. Maguire2, B. Daugherty2, S. Lederman2, R. Pierson III1

    1Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA, 2Tonix Pharmaceuticals, Chatham, NJ

    *Purpose: Blockade of the CD40/CD154 T cell costimulation pathway is a promising approach to replace current clinical immunosuppression. TNX-1500 (TNX) is a novel humanized anti-CD154…
  • 2022 American Transplant Congress

    Twelve Month Outcomes of Kidney Transplantation from Hepatitis C Viremic Deceased Donors to Aviremic Recipients

    L. A. Binari, R. C. Forbes, S. Rega, I. D. Feurer, A. Dreher, S. Shawar, H. Schaefer, D. Shaffer, B. P. Concepcion

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: The utilization of Hepatitis C viremic (HCV+) deceased donor kidneys for uninfected recipients allows for increased opportunities for organ transplantation. Initial studies have indicated…
  • 2022 American Transplant Congress

    Expanding Access to Robotic Kidney Transplantation for Candidates with High BMI. A Training Tool for Transplant Centers

    J. A. Almario Alvarez, G. Aguiluz, V. Valle, R. Bustos, S. Akshelyan, A. M. Fratti, P. D. Cocco, M. Spaggiari, I. G. Tzvetanov, E. Benedetti

    Surgery, University of Illinois at Chicago, Chicago, IL

    *Purpose: Recently published literature has demonstrated favorable outcomes for Robotic Kidney Transplant (RKT) in high BMI recipients. The University of Illinois at Chicago (UIC) has…
  • 2022 American Transplant Congress

    Gender Disparities in Kidney Transplantation Referral Vary by Age and Race in the Southeast US

    L. Smothers1, R. Patzer1, S. Pastan1, D. DuBay2, J. Harding1

    1Emory University, Atlanta, GA, 2Medical University of South Carolina, Charleston, SC

    *Purpose: Men (vs. women) are more likely to be waitlisted or receive a kidney transplant. Whether gender disparities exist in earlier transplant steps (i.e., referral)…
  • 2022 American Transplant Congress

    Financial Barriers Experienced During the Transplant Process by Caregivers of Children with End Stage Kidney Disease

    R. Goldfarb Terry1, A. Edwards1, U. Parlin2, A. Chung1, S. Amaral1

    1Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Known socioeconomic disparities in transplant referral and evaluation exist in adults with end-stage kidney disease, but little is known about the financial burden that…
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