Am J Transplant, Volume 22, Suppl 3 Archives - Page 115 of 190 - ATC Abstracts

2022 American Transplant Congress
Metastatic BK Virus-Associated Urothelial Carcinoma Originating in Renal Allograft
J. Torrealba¹, H. Jones¹, A. Bhakta², L. Jia¹, D. Wojciechowski²
¹Pathology, UT Southwestern, Dallas, TX, ²Internal Medicine, UT Southwestern, Dallas, TX
*Purpose: Cases of urinary tract carcinoma associated with BK virus have been reported in kidney transplant recipients; therefore, we postulate that BK virus may play…
2022 American Transplant Congress
Liver Transplantation is Beneficial Regardless of Cirrhosis Stage or Acute-on-Chronic Liver Failure Grade: A Single-Center Experience
E. Cervantes-Alvarez, O. Mendez-Guerrero, D. Kershenobich, A. Torre, M. Vilatobá, N. Navarro-Alvarez
Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
*Purpose: Liver transplantation for the most critically ill remains controversial; however, it is currently the only curative treatment option. The aim of this study was…
2022 American Transplant Congress
Extended Duration of Rabbit Antithymocyte Globulin (rATG) Induction in Kidney and Kidney/Pancreas Transplant Recipients
D. Majmundar, A. Di Carlo, A. Diamond
Temple University Hospital, Philadelphia, PA
*Purpose: Many transplant centers have endorsed an expanded duration of rabbit antithymocyte globulin (rATG) in the outpatient setting through peripheral administration to help minimize cost.…
2022 American Transplant Congress
OPO Education Spending and Donation Rates
J. Roberts¹, J. L. Bragg-Gresham², T. Peters³, F. McCormick⁴
¹University of California San Francisco, San Francisco, CA, ²University of Michigan, Ann Arbor, MI, ³University of Florida, Jacksonville, CA, ⁴Bank of America (former), Walnut Creek, CA
*Purpose: The shortage of organs for transplantation in the United States has endured for decades despite the efforts of transplantation professionals, organ procurement organizations, volunteer…
2022 American Transplant Congress
Tolerance of Allogeneic Kidneys with Durable (>200 Days) Multilineage Chimerism and Bone Marrow Engraftment in Cynomolgus Macaques
Y. Tomori¹, Y. Hisadome¹, D. Eisenson¹, K. Takeuchi¹, K. Okubo¹, C. Huang², D. Sachs¹, M. Sykes¹, K. Yamada¹
¹CCTI/Surgery and Medicine, Columbia University, New York, NY, ²University of Colorado Denver, Aurora, CO
*Purpose: We have previously reported that a regimen including anti-CD3 immunotoxin, 45 days of cyclosporine, and pre-transplant total body irradiation (TBI) promoted tolerance of kidney…
2022 American Transplant Congress
Development of an M2 Macrophage Signature in Spontaneously Accepted Kidney Allografts
M. T. Guinn¹, E. S. Szuter¹, T. Yokose¹, J. Ge², B. Kwon¹, I. Rosales³, P. S. Russell¹, A. G. Cuenca², J. C. Madsen⁴, R. B. Colvin³, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Boston Children's Hospital, Boston, MA, ³Department of Pathology, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ⁴Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) are spontaneously accepted. We have recently shown that novel regulatory Tertiary Lymphoid…
2022 American Transplant Congress
Immunogenicity of a Quadrivalent Human Papillomavirus Vaccine in Pediatric Kidney and Liver Transplant Recipients
T. Kitano¹, K. Schwartz², M. Abdulnoor¹, H. Garfield³, N. K. Booran¹, Y. Avitzur¹, C. Teoh¹, D. Hebert⁴, U. Allen³
¹Hospital for Sick Children, Toronto, ON, Canada, ²Public Health Ontario, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Solid-organ transplant recipients are at increased risk of developing human papillomavirus (HPV)-related diseases. The immunogenicity of HPV vaccine for solid-organ transplant population needs further…
2022 American Transplant Congress
Oseltamivir for the Prevention of Influenza Infection in Lung Transplant Recipients at an Academic Medical Center
D. Majmundar, A. Mishkin, J. Burnell, C. Ruggia-Check, J. Au
Temple University Hospital, Philadelphia, PA
*Purpose: Influenza is commonly considered a community acquired infection, but in transplant recipients, nosocomial transmission is frequently encountered. The lung transplant program at Temple University…
2022 American Transplant Congress
Alloimmune Recognition Blocks Recipient Macrophage Differentiation into Reparative Subsets
J. Warunek¹, A. Lucas², L. R. Mathews², M. Oberbarnscheidt², F. Lakkis², H. Turnquist²
¹Immunology, Thomas E. Starzl Transplantation Institute, University at Pittsburgh, Pittsburgh, PA, ²Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA
*Purpose: Monocytes differentiate into macrophage subsets that orchestrate tissue repair in response to damage signals and local cytokines. After heart transplant (Tx), graft IL-33 acts…
2022 American Transplant Congress
Evs from Patients with Amr Induce Tubular Senescence and Endmt Through Horizontal Transfer of Mirnas
R. Franzin¹, A. Stasi¹, F. Sallustio¹, S. Bruno², G. Merlotti³, M. Quaglia³, G. Grandaliano⁴, P. Pontrelli¹, J. Thurman⁵, G. Camussi², G. Stallone⁶, V. Cantaluppi³, L. Gesualdo¹, G. Castellano⁷
¹DETO, University of Bari, Bari, Italy, ²University of Turin, Turin, Italy, ³University of Piemonte Orientale, Novara, Italy, ⁴Università Cattolica Sacro Cuore, Rome, Italy, ⁵University of Colorado School of Medicine, Aurora, CO, ⁶University of Foggia, Foggia, Italy, ⁷University of Milan, Milan, Italy
*Purpose: Extracellular vesicles (EV) are emerging mediators in several diseases; however, their role in antibody-mediated allograft rejection (AMR) has been poorly investigated.*Methods: Plasma EVs from…