2022 American Transplant Congress
Polarized Il-6 Secretion from Lymphatic Endothelial Cells Promotes Treg Conversion to Extregs
1University of Maryland School of Medicine, Baltimore, MD, 2University of Minnesota, Minneapolis, MN
*Purpose: Regulatory T cell (Treg) suppressor function and allograft protection depend on maintenance of transcription factor Foxp3 expression and lymphatic migration. Lymphatic endothelial cell (LEC)…2022 American Transplant Congress
Predictors of Delayed Kidney Graft Function Following Combined Liver and Kidney Transplantation
*Purpose: Combined liver and kidney transplantation (CLKT) improves the survival in liver transplant recipients with renal dysfunction. However, kidney DGF (kDGF) still represents a common…2022 American Transplant Congress
An Initial Analysis of Baseline Levels of Dd-cfdna After Pancreas Transplantation: A Prospective Study from High-Volume Centers in the United States
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) testing, which has been validated for monitoring kidney transplant (KTx) rejection, may provide an alternative to pancreas biopsy that prevents…2022 American Transplant Congress
Alcohol Renal Syndrome: Alcohol Related Liver Disease for Liver Transplant is Associated with Renal Dysfunction
Westchester Medical Center / New York Medical College, Valhalla, NY
*Purpose: Liver transplantation (LT) due to alcohol related liver disease (ALD) has been increasing in the US. Alcohol has been known to increase the risk…2022 American Transplant Congress
Incidence of Posttransplant Lymphoproliferative Disorder with Belatacept Therapy versus Calcineurin Inhibitor Therapy Alone: Data from One Academic Medical Center
*Purpose: To compare rates of post-transplant lymphoproliferative disorder (PTLD) in patients treated with Belatacept and low-dose calcineurin inhibitors (CNIs) versus patients only treated with standard-dose…2022 American Transplant Congress
Validation of Shared T Cell Epitope Analysis as a Tool to Detect Preformed Donor-Reactive CD4+ Memory T-helper Cells
*Purpose: Adaptive immunity creates immunological memory after the first response to a specific foreign antigen including HLA. During this response, adaptive immunity memorizes the molecular…2022 American Transplant Congress
Clinical Outcomes In A Large Transplant Cohort Hospitalized With COVID-19: Mycophenolate Mofetil (MMF) Utilization And Mortality Trends
*Purpose: To characterize demographics, treatment patterns, and outcomes among 3,998 transplant patients hospitalized for COVID-19 over 16 months of the pandemic (May ’20-Aug ’21).*Methods: Adult…2022 American Transplant Congress
Three‐Month Pancreas Graft Function Significantly Influences Survival Following Simultaneous Pancreas‐Kidney Transplantation in Type 1 Diabetes Patients
1Washington University in St. Louis, Saint Louis, MO, 2Saint Louis University, Saint Louis, MO
*Purpose: Simultaneous pancreas-kidney transplantation (SPK) is the only persistently successful treatment option for patients with diabetes mellitus and end-stage renal disease. However, SPK carries a…2022 American Transplant Congress
Prediction of Waitlist Mortality in Liver Transplant Candidates: Do Time-Varying Models Help?
*Purpose: In the United States, priority on the liver transplant waitlist is determined by the model for end-stage liver disease (MELD)-Na, a score composed of…2022 American Transplant Congress
Immune Checkpoints, Immune Cells, and MHC Expression in the Tumor Microenvironment of Resected Hepatocellular Carcinomas
*Purpose: Advances in tumor biology has shown the important role of the tumor microenvironment (TME) in tumor growth and metastasis. A better understanding of the…
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