ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Establishing a New Hepatobiliary Surgery Program in a Level 1 Trauma Center Community Teaching Hospital (Our Open and Robotic Experience)

    J. S. Han, S. A. Neubauer, C. E. Renner, C. M. Dunham, T. J. Chirichella

    General Surgery, St. Elizabeth Youngstown Hospital, Youngstown, OH

    *Purpose: To improve access to quality care, the surgical outcomes and influencing factors were investigated for a new hepatobiliary surgery program established by a transplant…
  • 2022 American Transplant Congress

    Real-Time Biometric Monitoring Using Wearable Devices for Pediatric Heart Transplant Rejection and Infection Surveillance

    D. Gandla1, J. B. Edelson2, E. Mukhtar1, J. Callanan1, H. Lad1, H. Gao1, J. Cornetta1, B. Keating1

    1Department of Surgery, Perelman School of Medicine, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Monitoring for acute rejection (AR) after orthotopic heart transplantation (OHTx) is primarily achieved by evaluating histological endomyocardial biopsies (EMBx). However, this procedure is limited…
  • 2022 American Transplant Congress

    Similar Outcomes in Type 2 Diabetic vs Type 1 Diabetics Receiving Simultaneous Kidney Pancreas Transplantation

    P. Budhiraja1, H. Me1, J. Ninan2, S. Reddy2, S. S. Misra1, R. Heilman1, H. Khamash1, K. Reddy1, C. Jadloweic1, N. Katariya1, H. Chakkera1

    1Mayo Clinic, Phoenix, AZ, 2Mayo Clinic, Rochester, MN

    *Purpose: Combined kidney-pancreas transplant remains an optimal choice for type 1 diabetics with kidney failure. The benefit for those with type 2 diabetes, however, remains…
  • 2022 American Transplant Congress

    Prebiotic Supplementation In Kidney Transplant Recipients For Preventing Infections And Gastrointestinal Upset: A Randomized Controlled Feasibility Study

    S. Chan1, C. M. Hawley1, E. M. Pascoe2, C. Z. Cao2, S. B. Campbell2, K. L. Campbell3, R. S. Francis2, R. Hale1, N. M. Isbel4, M. Morrison5, D. W. Johnson2

    1Department of Nephrology, Princess Alexandra Hospital, Woolloongabba, Australia, 2Princess Alexandra Hospital, Woolloongabba, Australia, 3Menzies Health Institute - Molecular Basis of Disease Research Program, Griffith University, Brisbane, Australia, 4Princess Alexandra Hospital, Brisbane, Australia, 5Diamantina Institute, Faculty of Medicine, The University of Queensland, Woolloongabba, Australia

    *Purpose: Modulating the large intestinal microbiome of kidney transplant recipients (KTR) may reduce infectious complications. The aim of this study was to assess the feasibility…
  • 2022 American Transplant Congress

    The Impact of T-Cell Receptor Diversity in Acute Kidney Transplant Rejection

    T. Sigdel1, P. Fields2, J. Liberto1, I. Damm1, M. Kerwin1, j. Hood2, P. Towfighi1, M. Sirota1, H. Robins2, M. M. Sarwal1

    1UCSF, San Francisco, CA, 2Adaptive Biotechnologies, Seattle, WA

    *Purpose: Recent developments in T-cell receptor (TCR) immunosequencing allow for analysis of alloreactive human T-cell populations both before and after engraftment. In this study, we…
  • 2022 American Transplant Congress

    Associations of Immunosuppression Regimen with Fracture Risk After Kidney Transplant in High-Risk Populations: Identifying Targets for Risk-Reduction

    K. Lentine1, S. Kupacchi2, W. Cheungpasitporn3, R. Li4, Y. Caliskan4, M. Schnitzler4, M. McAdams-DeMarco5, J. Ahn5, S. Bae6, G. Hess7, D. Segev5, D. Axelrod2

    1Saint Louis University Center for Abdominal Transplantation, St. Louis, MO, 2U Iowa, Iowa City, IA, 3Mayo Clinic, Rochester, MN, 4Saint Louis University, Saint Louis, MO, 5Johns Hopkins, Baltimore, MD, 6Johns Hopkins, Baltimore, MO, 7Drexel, Philadelphia, MO

    *Purpose: Disorders of bone and mineral metabolism frequently develop with advanced kidney disease, may be exacerbated by immunosuppression (ISx) after kidney transplant (KTx), and may…
  • 2022 American Transplant Congress

    Correlation of Non-HLA Antibodies and Biopsy-Proven Antibody-Mediated Rejection

    N. Patel, M. Kittleson, J. Patel, T. Singer-Englar, S. Kim, D. Chang, E. Kransdorf, D. Megna, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Non-HLA antibodies are seen in heart transplantation (HTx), but the clinical significance has not been established. In many cases, non-HLA antibodies are drawn, but…
  • 2022 American Transplant Congress

    Concordance of POLQ and PARP-1 Expression and MMEJ Type Viral Integration in the Progression of BKPyV-Associated Diseases

    Y. Wang1, Z. Yan1, Y. Liu2, J. Geng3, W. Deng1, R. Xia1, W. Zeng1, J. Xu1, C. Wu4, Y. Miao1

    1Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, 2Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China, 3Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China, 4Departments of Urology & Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    *Purpose: To reveal the mechanism of the increasing dominant position of integration, especially the microhomology-mediated end joint (MMEJ) form in the development of BK Polyomavirus…
  • 2022 American Transplant Congress

    Pretransplant Rifaximin Treatment Improves Liver Transplant Outcomes in Mice and Humans

    H. Kojima, S. Kageyama, T. Ito, D. Noguchi, H. Hirao, K. Kadono, K. J. Dery, F. Kaldas, J. Kupiec-Weglinski

    UCLA Medical Center, Los Angeles, CA

    *Purpose: We recently reported modifications of the gut microbiota by amoxicillin influences liver allograft function. Rifaximin (RFX), a nonabsorbable oral antimicrobial agent with a low…
  • 2022 American Transplant Congress

    Effects of Race, Previous CoV2 Exposure and the Length and Type of Maintenance Immunosuppression on Protective Immunity to COVID19 Vaccine in Solid Organ Transplant Recipients

    A. Choudhary1, M. Lerman2, S. Khan2, J. Hunt2, A. Nikaein3, D. Calianese1, E. Kalu2, D. K. Jaijyan4, W. Honnen1, A. Pinter1

    1PHRI, Rutgers University, Newark, NJ, 2Transplant, Medical City Dallas, Dallas, TX, 3Texas Speciality, Medical City Dallas, Dallas, TX, 4pHRI, Rutgers University, Newark, NJ

    *Purpose: The diverse factors affecting the vaccine induced neutralizing antibody response in solid organ transplant recipients and their immunity against CoV2 variants are needed to…
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