Am J Transplant, Volume 22, Suppl 3 Archives - Page 107 of 190 - ATC Abstracts

2022 American Transplant Congress
Pre-Transplantation Liver Immunoadsorption Reduces Liver-Specific Antibody and Complement Deposition without Prolonging Survival in Porcine to Baboon Liver Xenotransplantation
D. J. Cloonan¹, T. Coe¹, N. Serifis¹, R. Matheson¹, S. Maggipinto¹, D. Firl¹, R. Anand², J. Layer², L. Queiroz², K. Stiede², K. Hall², M. Youd², W. Qin², M. Curtis², S. Kimura¹, I. Rosales¹, J. Markmann¹
¹Massachusetts General Hospital/Harvard Medical School, Boston, MA, ²eGenesis, Inc, Cambridge, MA
*Purpose: Triple knock-out pigs lacking GGTA1, β4GALNT2, CMAH genes are hypothesized to be the optimal donor for human xenotransplantation, however there is evidence that TKO…
2022 American Transplant Congress
Re-Kidney Transplantation in Patients with Graft Failure: Survival Benefit by Age
J. Ahn¹, S. Sandal², A. Massie¹, D. Segev¹, M. Cantarovich², M. McAdams-DeMarco¹
¹Johns Hopkins University, Baltimore, MD, ²McGill University, Montreal, QC, Canada
*Purpose: As the rates of kidney transplantation (KT) have doubled over the past three decades, so has the proportion of patients who experience graft failure…
2022 American Transplant Congress
Research Publication Rates, Characteristics, and Perceptions of Solid Organ Transplant Pharmacy Residency Training: A Survey of Program Directors
J. Melaragno¹, D. Kovac², S. Witek³, M. Harris⁴, K. Khalil⁵, M. Laub⁶, D. Quan⁷, A. Lichvar⁸
¹University of Rochester, Rochester, NY, ²NewYork-Presbyterian Hospital, New York, NY, ³Inova Fairfax Hospital, Falls Church, VA, ⁴Duke University Hospital, Durham, NC, ⁵NYU Langone Health, New York, NY, ⁶Augusta University Medical Center, Augusta, GA, ⁷UCSF Medical Center, San Francisco, CA, ⁸UCSD Health, San Diego, CA
*Purpose: The purpose of this study was to determine the publication rate of post-graduate year 2 (PGY2) transplant pharmacy residents, to characterize current practices surrounding…
2022 American Transplant Congress
Outcomes of Very Small Pediatric Donor Kidneys Utilizing Belatacept-Based Immunosuppression in Adult Recipients
K. Heinen¹, A. Carlson², A. Chan¹, M. M. Eiting¹, T. Larson¹, B. Sirandas¹, C. Truax¹, L. Smith¹
¹University of Utah Health, Salt Lake City, UT, ²Medical University of South Carolina, Johnston, SC
*Purpose: Due to the lack of data utilizing belatacept as primary immunosuppression for adult recipients of very small pediatric donor kidneys, this study seeks to…
2022 American Transplant Congress
Outcomes and Management of Salmonella Enteritis Following Solid Organ Transplantation
M. Musleh¹, F. Nimri¹, A. Elbanna², S. Jafri²
¹Internal Medicine, Henry Ford Health System, Detroit, MI, ²Gastroenterology, Henry Ford Health System, Detroit, MI
*Purpose: Evaluate the outcomes of patients who developed salmonella infection post solid organ transplant.*Methods: A retrospective single-center study was conducted at a tertiary transplant center.…
2022 American Transplant Congress
Meta-Analysis of the Chronic Exposure to Calcineurin Inhibitors and the Risk for Chronic and End-Stage Kidney Disease in Non-Renal Solid Organ Transplant Recipients
A. Alvarez Elias¹, M. Riedl¹, D. Stewart², A. Ruco³, P. Bobos³, S. Maharaj⁴, V. Shah⁵, E. Uleryk⁶, C. Teoh¹, R. Parekh¹
¹Hospital for Sick Children, Toronto, ON, Canada, ²Royal Hospital for Children, Glasgow, United Kingdom, ³St. Michael’s Hospital, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵Mount Sinai Hospital, Toronto, ON, Canada, ⁶E. M. Uleryk Consulting, Toronto, ON, Canada
*Purpose: Calcineurin inhibitors (CNI) are standard of care immunosuppressants among all solid organ transplant (SOT) recipients, and the most common side effect is nephrotoxicity. There…
2022 American Transplant Congress
Long Term Longitudinal TTV Measurements in Lung Transplant Recipients
E. Gore¹, C. Rondaan¹, E. A. Verschuuren², L. Gard¹, H. G. Niesters¹, C. van Leer-Buter¹
¹Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands, ²Department of Pulmonary Diseases and Tuberculosis, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands
*Purpose: To investigate how levels of Torque Teno Virus (TTV), a virus which has been proposed as a marker for immunosuppression change over a period…
2022 American Transplant Congress
PCR-Enhanced Performance Characteristics of TruGraf Gene Expression Profile in Kidney Transplant
P. West-Thielke¹, J. Fleming¹, C. Miller¹, N. Grund¹, A. Sutton¹, R. Sinha², M. Miller², S. Kleiboeker², J. Weems³
¹Transplant Genomics, Inc., Framingham, MA, ²Eurofins-Viracor, Lees Summit, MO, ³Transplant Genomics, Inc., Lees Summit, MO
*Purpose: The aim of this study was to perform clinical validation of TruGraf GEP using PCR methodology, as compared to the previously used microarray methodology,…
2022 American Transplant Congress
Technology-Driven Performance Improvement of a Biomarker Panel in Kidney Transplant: OmniGraf
P. West-Thielke, C. Miller, N. Grund, A. Sutton, R. Sinha, M. Miller, S. Kleiboeker, J. Weems
Eurofins, Framingham, MA
*Purpose: Analyze the impact of the transition from TruGraf microarray to TruGraf PCR on the complementary performance characteristics of TruGraf plus TRAC (OmniGraf).*Methods: Development of…
2022 American Transplant Congress
A Novel Mismatch That Modulates the Innate Alloresponse Risk Stratifies Renal Transplant Patients
H. Dai, K. Abou Daya, M. Oberbarnscheidt, R. Mehta, C. Macedo, D. Metes, Q. Xu, A. Zeevi, P. Randhawa, F. Lakkis, A. Cherukuri
Thomas E. Starzl Transplantation Institute, UPMC, Pittsburgh, PA
*Purpose: Donor polymorphism in the gene encoding signal regulatory protein alpha (SIRPα) is a key modulator of the recipient’s innate alloresponse. Here, we investigated the…