ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Post-Transplant Outcomes and Financial Burden in Donation After Cardiac Death Donor Liver Transplant After the Implementation of Acuity Circle Allocation Policy

    S. Shimada, T. Shamaa, T. Ivanics, T. Kitajima, M. Adhnan, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai

    Division of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: The use of donation after cardiac death (DCD) donor liver grafts has been increasing in many transplant centers after introducing the acuity circles (AC)…
  • 2022 American Transplant Congress

    Perturbing Proteostasis to Deplete Plasma Cells

    A. Rossi1, A. Burg1, K. Roskin1, A. Shields2, R. Alloway2, E. Woodle2, D. Hildeman1

    1Cincinnati Children's Hospital, Cincinnati, OH, 2University of Cincinnati College of Medicine, Cincinnati, OH

    *Purpose: Alloantibodies play critical roles in rejection and often prevent sensitized patients from receiving life-sustaining transplants. One approach for enhancing transplantation rates and survival for…
  • 2022 American Transplant Congress

    Implanting a Robot-Assisted Kidney Transplant Program for ASTS Trained Transplant Surgeons with No Robotic Surgery Background

    B. Kocak1, N. Celik1, E. Arpali1, B. Akyollu1, B. Kilicer1, E. Canda2, Y. Kordan2

    1Division of Organ Transplantation, Koc University Hospital, Istanbul, Turkey, 2Department of Urology, Koc University Hospital, Istanbul, Turkey

    *Purpose: Robot-assisted kidney transplantation (RAKT) was introduced and has been performed commonly by surgeons experienced with robotic surgery and with this single center study we…
  • 2022 American Transplant Congress

    Recipient Race Modifies the Association Between Obesity and Long Term Graft Outcomes After Renal Transplantation

    F. Jarrar1, K. Tennankore2, A. J. Vinson3

    1Dalhousie University, Halifax, NS, Canada, 2Nova Scotia Health Authority, Halifax, NS, Canada, 3Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada

    *Purpose: Both donor and recipient obesity are associated with adverse outcomes after transplant. Whether obesity, defined using body mass index (BMI), has different implications on…
  • 2022 American Transplant Congress

    Real-Time Application of Deep Learning in Diagnosis of Graft Fibrosis After Liver Transplantation Using Longitudinal Data

    A. Azhie1, D. Sharma2, P. Sheth1, W. Xu3, M. Bhat1

    1Ajmera Transplant Program, University Health Network, Toronto, ON, Canada, 2Department of Biostatistics, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada, 3Biostatistics Division, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

    *Purpose: Graft fibrosis develops insidiously in liver transplant recipients and is associated with worse survival. Early detection of fibrosis is essential to avoid further progression…
  • 2022 American Transplant Congress

    Top Molecules Associated with CLAD in Lung Transplants Are Shared Between Mucosal Biopsies, Transbronchial Biopsies, and Kidney Transplant Biopsies at Risk of Progression

    M. Mackova1, K. Halloran2, P. F. Halloran1, .. and the INTERLUNG Study Group3

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2University of Alberta, Edmonton, AB, Canada, 3., ., AB, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD) is a physiologic state with grave consequences for progression to failure but cannot be diagnosed by biopsy histology. We…
  • 2022 American Transplant Congress

    Donor-Derived Carbapenem-Resistant Gram-Negative Infections: Risk Mitigation Strategy in Solid Organ Transplant Improves Recipients Safety and Could Expand Donor Pool

    A. Mularoni1, E. Graziano1, M. Campanella1, A. Cervo2, M. Peghin3, F. Barbera1, P. Conaldi1, A. Luca1, P. A. Grossi4

    1ISMETT, Palermo, Italy, 2Department of Infectious Diseases, Azienda Ospedaliero-Universitaria Policlinico of Modena, Modena, Italy, 3Division of Infectious Diseases, ASUFC, Udine, Italy, 4Infectious and Tropical Diseases Unit, University of Insubria, Varese, Italy

    *Purpose: We implemented an Active Surveillance System (ASS) to mitigate the risk of unexpected carbapenem-resistant Gram-negative (CRGN) donor-derived infection (DDI) in solid organ transplant recipient…
  • 2022 American Transplant Congress

    Upregulation of Innate Immune Pathways is Associated with Increased Rejection in HIV-Infected Kidney Transplant Recipients

    A. Zarinsefat1, Y. Kelly1, D. Dobi1, G. Szabo1, Z. Laszik1, P. Stock1, H. Braun2

    1UC San Francisco, San Francisco, CA, 2CA

    *Purpose: Although kidney transplantation (KT) has become the standard of care for HIV+ patients with renal failure, early experiences revealed high acute rejection (AR) rates.…
  • 2022 American Transplant Congress

    Treg Tissue Stability Depends on Adenosine Receptor Driven Lymphatic Endothelial Cell Responses

    V. Saxena1, W. Piao1, L. Li1, M. W. Shirkey1, R. Lakhan1, S. Walden2, K. L. Hippen2, B. R. Blazar2, J. S. Bromberg1

    1University of Maryland School of Medicine, Baltimore, MD, 2University of Minnesota, Minneapolis, MN

    *Purpose: Regulatory T cell (Treg) lymphatic migration and maintenance of transcription factor Foxp3 expression are required for suppressor function and allograft protection. Migrating Tregs were…
  • 2022 American Transplant Congress

    Recipient TIM4+ Macrophage is a Central Hub for Metabolic Homeostasis in Liver Transplantation: From Mouse-to-Human

    H. Hirao, K. Kadono, H. Kojima, K. J. Dery, D. G. Farmer, F. M. Kaldas, J. Kupiec-Weglinski

    UCLA, Los Angeles, CA

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major risk factor for early graft dysfunction and predisposes to rejection in orthotopic liver transplantation (OLT). Previous studies…
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