2022 American Transplant Congress
T-cell Depletion vs. Il-2 Receptor Blockade in Pancreas Transplantationt-Cell Depletion vs. Il-2 Receptor Blockade in Pancreas Transplantation
University of Wisconsin, Madison, WI
*Purpose: Because of the higher immunological risk associated with pancreas compared to kidney transplantation, many have assumed that T depleting induction is required for pancreas…2022 American Transplant Congress
Is BK After SPK Okay?: Kidney and Pancreas Transplant Outcomes After BK Viremia
*Purpose: BK viremia and BK nephropathy (BKN) are common after kidney transplant alone, occurring in ~15% and ~1-10%, and are associated with an increased risk…2022 American Transplant Congress
Comparative Outcomes at a Single Center for 71 Deceased Donor Kidney Transplants from Donors with Sars-CoV-2 RNA Detection
*Purpose: Extra-pulmonary organs from donors with SARS-CoV-2 detection during donor evaluation are not accepted by many centers due to theoretical concerns for productive infection and…2022 American Transplant Congress
Molecular Associations in Kidney Transplant Biopsies in the Trifecta Study Indicate That at Least Three Distinct Processes Release Dd-cfDNA: ABMR, TCMR, and Injury
*Purpose: In the Trifecta study (ClinicalTrials.gov # NCT04239703 53), elevated plasma dd-cfDNA is associated with molecular rejection in kidney transplant indication biopsies, particularly active ABMR…2022 American Transplant Congress
Does Machine Perfusion of Heart for Donation After Cardiac Death (DCD) Transplantation Affect Other Organ Outcomes?
*Purpose: Machine perfusion of heart for donation after cardiac death (DCD) transplants is being increasingly utilized. Initial protocol of the heart machine perfusion for the…2022 American Transplant Congress
Impaired Cellular Immunity and Elevated Myeloid Derived Suppressor Cells in Kidney Transplant Recipients with Impaired Antibody Response to Covid-19 Vaccination
1AdventHealth Transplant Institute, Orlando, FL, 2Plexision, Inc, Pittsburgh, PA
*Purpose: To evaluate post-vaccination cellular and antibody (Ab) immunity after COVID-19 vaccination in single blood samples from 17 kidney transplant (KT) recipients who had received…2022 American Transplant Congress
A Composite Endpoint to Improve Upon the Srtr 5-Tier Rating System
*Purpose: Kidney transplant program performance in the US is monitored with outcome metrics used by regulatory agencies to assess provider quality and by patients to…2022 American Transplant Congress
Combined Genome Wide and Single Nuclei Transcriptomics in Posttransplant Acute Kidney Injury Identifies Early Proinflammatory/Profibrogenic Cell Origin
*Purpose: Kidney transplants offer a unique opportunity to evaluate molecular pathways involved in development and response to acute kidney injury (AKI). This prospective study of…2022 American Transplant Congress
Leveraging Car T Cells To Achieve Desensitization And Enable Transplantation
UNIVERSITY OF PENNSYLVANIA, PHILADELPHIA, PA
*Purpose: Pre-existing allo-antibodies (allo-Abs), that preclude transplant due to the risk of hyperacute rejection, lead to prolonged wait times and high mortality rates. Current desensitization…2022 American Transplant Congress
The Effect of Bariatric Surgery Pre-Transplant on Renal Transplant Outcomes
Surgery, McGill, Montreal, QC, Canada
*Purpose: We compared post-transplant outcomes in patients with morbid obesity undergoing pre-transplant bariatric surgery to non-obese and obese patients without bariatric surgery.*Methods: Adult recipients of…
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