2022 American Transplant Congress
The Acuity Circle Allocation Policy is Associated with Worse Graft Survival After Liver Transplant with Donation After Circulatory Death Donors in Low-MELD Centers
*Purpose: Liver allocation in the United States was updated in February of 2020, with introduction of the acuity circle (AC) model. However, the effect of…2022 American Transplant Congress
CoVID-19 Vaccine Efficacy in Heart Transplant Recipients, a Single Center Experience
*Purpose: Transplant recipients have worse CoVID-19 survival compared to the general population, and thus are recommended to be vaccinated and boosted. Determinants of vaccination efficacy…2022 American Transplant Congress
BK Polyomavirus and Cytomegalovirus Infections in Kidney Transplantation from Hepatitis C Positive Donors to Uninfected Recipients
Virginia Commonwealth University, Richmond, VA
*Purpose: Transplantation of hepatitis C viremic (HCV) donor kidneys into uninfected recipients (D+/R-) is becoming more common in the United States. However, the long-term risks…2022 American Transplant Congress
Novel Immune Checkpoint Molecule TIGIT Mediates Experimental Kidney Ischemia Reperfusion Injury
Medicine, Johns Hopkins University, Baltimore, MD
*Purpose: T cells play both pathogenic and reparative roles in kidney ischemia reperfusion injury (IRI) but the molecular mechanisms regulating kidney T cell functions are…2022 American Transplant Congress
Trajectory Analysis Of Single Cell RNAseq Data Suggest Intrarenal Induction Of Tregs In Spontaneously Accepted Kidney Allografts
*Purpose: Kidney allografts transplanted across certain mouse strain combinations (e.g. DBA/2 to B6) are spontaneously accepted independent of the recipient’s thymus, spleen, and lymph nodes.…2022 American Transplant Congress
Renal Function at Five Years from a Randomized Multicenter Trial of Belatacept-Based CNI Free and Early Steroid Withdrawal Immunosuppression
1University of Cincinnati, Cincinnati, OH, 2Christ Hospital, Cincinnati, OH
*Purpose: BENEFIT and BENEFIT EXT trials have demonstrated that belatacept-based immunosuppression was associated with improved long term renal allograft function compared to cyclosporine-based immunosuppression. Similar…2022 American Transplant Congress
Quantification of Center Aggressiveness in Accepting Sub-Optimal Kidney Donations from Deceased Donors in the US
*Purpose: Understanding center-level differences in usage of marginal deceased-donor kidneys (suboptimal kidneys, SOK) can help centers increase their deceased-donor transplant rate (DDKT), and to direct…2022 American Transplant Congress
Variation in Immunosuppressive Regimen in Children Receiving Liver Transplants: An Analysis of the UNOS Database
*Purpose: Optimizing immunosuppression (IS) was identified as a priority for pediatric liver transplant (LT) families and providers in the Starzl Network, a multi-center learning health…2022 American Transplant Congress
Surveillance with Protocol Biopsies for Rejection Significantly Impacts Survival Following Intestine Transplant
*Purpose: Frequent surveillance biopsy is required on the first month post intestinal transplant(IT) due to high-risk of acute rejection. However, the utility and the frequency…2022 American Transplant Congress
Novel Portable Hypothermic Cardiac Preservation Device Enhances Cardiac Viability and Function of the Isolated Porcine Hearts
Vascular Perfusion Solutions, Inc, San Antonio, TX
*Purpose: Cardiac heart transplantation is the gold standard for treating end-stage heart failure; however, the list of patients waiting for heart transplants continues to increase.…
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