ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    A Meta-Analysis of Endoscopic Stents in the Treatment of Anastomotic Biliary Strictures After Liver Transplantation

    F. Zhou1, M. Mieth1, C. Rupp2, A. Mehrabi1, A. Nickkholgh1

    1Department of General, Abdominal and Transplant Surgery, University of Heidelberg, Heidelberg, Germany, 2Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany

    *Purpose: Biliary strictures (BS) are common after orthotopic liver transplantation (OLT). The treatment of choice is endoscopic retrograde cholangiopancreatography (ERCP). Multiple plastic stents (MPS) have…
  • 2021 American Transplant Congress

    Beneficial Effects of Argon Inhalation on Reducing Lung Ischemia-reperfusion Injury in Miniature Swine

    H. Sahara

    Div. Organ Replacement and Xeno Tx, Center for Advanced Biomedical Science and Swine Research, Kagoshima University, Kagoshima, Japan

    *Purpose: Noble gases, such as xenon and argon (Ar), are chemically inert but have shown to have cytoprotective effect. In contrast to xenon, Ar is…
  • 2021 American Transplant Congress

    Long Term Outcomes of Kidney Donors with Fibromuscular Dysplasia

    H. N. Adrogue1, A. Evans1, S. A. Hebert1, H. E. Adrogue1, D. T. Nguyen2, D. Murad1, E. A. Graviss2

    1Medicine, Houston Methodist Hospital, Houston, TX, 2Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX

    *Purpose: Fibromuscular dysplasia (FMD) is not an infrequent finding during kidney donor evaluation. Current guidelines do not provide any recommendations regarding the use of kidneys…
  • 2021 American Transplant Congress

    Economic Impact of a Pharmacist-Led Medication Safety Intervention: Report from the Transafe Rx Randomized Controlled Trial

    D. Taber, J. Fleming, Z. Su, P. Mauldin, M. Gebregziabher

    Med Univ of South Carolina, Charleston, SC

    *Purpose: We have previously demonstrated the efficacy of a pharmacist-led, mHealth intervention on reducing medication errors and adverse events leading to reduce hospitalizations in kidney…
  • 2021 American Transplant Congress

    Complement Blockade Improves Renal Xenograft Survival in Primates in the Absence of Transgenic Complement Regulatory Proteins

    D. A. Faber1, B. Lovasik1, A. Matar1, C. Breeden1, A. B. Farris2, M. Tector3, A. Tector3, A. Adams4

    1Surgery, Emory University School of Medicine, Atlanta, GA, 2Pathology, Emory University School of Medicine, Atlanta, GA, 3Surgery, University of Miami, Miami, FL, 4Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Complement activation is a major contributor to xenograft rejection. To minimize xenograft injury, complement suppression via insertion of human complement-regulatory transgenes into the donor…
  • 2021 American Transplant Congress

    Belatacept for Kidney Transplantation in the Age of Covid19, is it Safe?

    J. Pagan1, S. Anjan2, Y. Natori3, A. Fernandez3, R. Zamora-Gonzalez2, A. Mattiazzi1, L. Mendez1, G. Guerra1

    1Nephrology, University of Miami, Miami, FL, 2Infectious Diseases, University of Miami, Miami, FL, 3Infectious Disease, University of Miami, Miami, FL

    *Purpose: The COVID19 pandemic has affected kidney transplant recipients (KTR) with a wide spectrum of clinical severity. Up to this point, we have solely seen…
  • 2021 American Transplant Congress

    Frailty and Short-Term Outcomes in Kidney Transplant

    S. Van Arsdale1, K. Torbert1, R. Harland2, A. Turner2, B. Tanriover3, V. Ariyamuthu3

    1Banner University Medical Center, Tucson, AZ, 2Surgery, Banner University Medical Center, Tucson, AZ, 3Internal Medicine, Banner University Medical Center, Tucson, AZ

    *Purpose: Studies suggest worse outcomes for frail solid organ transplant recipients. We analyzed post transplant outcomes in relation to frailty.*Methods: We conducted a retrospective study…
  • 2021 American Transplant Congress

    Pharmacokinetic and Toxicity Studies of an Anti CD40L Antibody, At-1501 in Rhesus Macaques

    S. Perrin1, A. Gill2, C. Gill2, F. Vieira2, K. Thompson2

    1Novus Therapeutics, Irvine, CA, 2ALS Therapy Development Institute, Cambridge, MA

    *Purpose: CD40L is a costimulatory receptor for CD40 found on T helper cells. Binding of CD40L on T cells to CD40 on antigen presenting cells…
  • 2021 American Transplant Congress

    Targeting Il-21 Receptor Shifts Tfh/tfr Balance and Ameliorateschronic Antibody Mediated Rejection

    Y. Nian, Z. Xiong, J. Zhao, Y. Fu

    Tianjin First Central Hospital, Tianjin, China

    *Purpose: Donor specific antibody (DSA) plays a central role in chronic kidney allograft injury. As a trigger of humoral alloimmune response, follicular T helper cells(Tfh)…
  • 2021 American Transplant Congress

    The Tumor-suppressor Signaling of the α1-na/k-atpase- Cav-1-src Complex at the Caveola in Nash Related Hepatocellular Carcinoma

    U. S. Udoh1, J. D. Sanabria1, M. Banerjee1, P. K. Rajan1, M. Schade1, J. A. Sanabria1, A. Mallick1, G. Smith1, G. U. Udoh2, K. Sodhi1, S. Pierre2, Z. Xie2, J. Shapiro2, J. Sanabria1

    1Dept. of Surgery/ Marshall Institute for Interdisciplinary Research, Marshall University, Huntington,, WV, 2Marshall Institute for Interdisciplinary Research, Marshall University, Huntington,, WV

    *Purpose: Hepatocellular Carcinoma (HCC) is the 2nd and fastest-growing cause of cancer related mortality worldwide, mainly from the metabolic cellular disturbances promoted by the epidemic…
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