ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Gene Expression Profiles Assessed by the Nanostring nCounter® Platform May Differentiate Different Types of Rejection, and Importantly, T-Cell Mediated Rejection from BK Virus Nephropathy

    K. R. Degner1, K. J. Swanson1, S. Parajuli1, D. Mandelbrot1, N. Garg1, F. Aziz1, M. Mohamed1, W. Zhong1, L. Ptak1, N. A. Wilson1, R. Woodward2, A. Djamali1

    1University of Wisconsin, Madison, WI, 2CareDx, Inc., San Francisco, CA

    *Purpose: Allograft biopsies are considered the gold standard for diagnosis and therapeutic guidance in kidney transplant recipients. Expanding current biopsy assessments to include gene expression…
  • 2021 American Transplant Congress

    The Assesment of Pre-transplant Donor-reactive IL-21 Producing T Cells as a Tool to Identify Patients at Risk for Acute Rejection

    A. Mendoza Rojas1, T. van Gelder2, R. de Kuiper1, D. Reijerkerk1, M. C. Clahsen-van Groningen3, D. A. Hesselink1, C. C. Baan1, N. M. van Besouw1

    1Internal Medicine, Neprology & Transplantation, Erasmus Medical Center, Rotterdam, Netherlands, 2Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, Netherlands, 3Internal Medicine, Pathology, Erasmus Medical Center, Rotterdam, Netherlands

    *Purpose: The measurement of panel-reactive antibodies (PRA) has proven valuable in the transplant setting but it does not account for the presence of donor-reactive memory…
  • 2021 American Transplant Congress

    Role of Trugraf Testing in Kidney Allografts Previously Biopsied for Dysfunction

    Y. A. Qazi1, W. Mon1, C. Choi1, S. Qazi2, M. Smogorzewski1

    1Keck Medical Center at USC, Los Angeles, CA, 2Keck Medical Center at USC, La Canada Flt, CA

    *Purpose: TruGraf®, can be used as an alternative to surveillance biopsies for ruling out “silent” subclinical acute rejections in transplant patients with stable graft function.…
  • 2021 American Transplant Congress

    Cellular and Genetic Signatures of Operational Tolerance in Kidney Transplant Recipients Through Single Cell R N A Sequencing Analysis

    H. BAE1, H. Lee2, J. Ryu3, B. Chung2, E. Oh3

    1Department of Biomedical Science, Graduate School, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of, 2Department of Internal Medicine, Division of Nephrology, College of Medicine, Seoul St. Mary’s hospital, the Catholic University of Korea, Seoul, Korea, Republic of, 3Department of Laboratory Medicine, College of medicine, The Catholic university of Korea, Seoul, Seoul, Korea, Republic of

    *Purpose: Patients with operational tolerance do not use immunosuppressants after renal transplantation, but they show stable post-transplant results. We analyzed differently expressed mRNAs and proteins…
  • 2021 American Transplant Congress

    Death and Loss to Follow-up in Pediatric Liver Transplant Recipients Transferred to Adult Care: Who is at Risk?

    J. P. Stevens1, S. Gillespie1, M. Katz1, L. Hall2, V. Kolachala1, R. Ford3, N. A. Gupta1

    1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Transplant Services, Children's Healthcare of Atlanta, Atlanta, GA, 3Internal Medicine, Emory University School of Medicine, Atlanta, GA

    *Purpose: With improvements in surgical technique and immunosuppressive regimens, many pediatric liver transplant recipients are surviving to adulthood. Successful transition to an adult provider is…
  • 2021 American Transplant Congress

    Primary Graft Dysfunction in a Risk-Stratified vs. Routine Induction Protocol in Heart Transplant Recipients

    J. S. van Zyl1, H. Zafar1, P. M. Nguyen2, J. Felius1, T. Sam3, S. A. Hall3

    1Baylor Scott & White Research Institute, Dallas, TX, 2Texas A&M University College of Medicine Health Science Center, Dallas, TX, 3Baylor Scott & White Health, Dallas, TX

    *Purpose: Treatment of left ventricular primary graft dysfunction (PGD-LV) is supportive in nature. We aim to evaluate whether a change in induction protocol from a…
  • 2021 American Transplant Congress

    Covid Studies in 208 Patients with Consent for Donation

    A. L. Friedman, C. Ezzell, K. Delli Carpini

    LiveOnNY, New York, NY

    *Purpose: To prevent transmission of SARS CoV 2 via solid organ donation from deceased donors.*Methods: Comprehensive medical and psychosocial evaluation of potential deceased organ donors…
  • 2021 American Transplant Congress

    Weathering the Cytokine Storm: Therapeutic Plasma Exchange for the Management of Severe Covid19 in Solid Organ Transplant Recipients

    A. Mattiazzi1, J. Pagan1, L. A. Mendez Castaner2, A. Fernandez1, R. Zamora Gonzalez1, J. Simkins1, L. Preczewski1, Y. Natori1, S. Anjan1, G. Guerra1

    1Miami Transplant Institute, Miami, FL, 2Miami Trasnplant Institute, Miami, FL

    *Purpose: The treatment of SARS-CoV-2 associated pneumonia in solid organ transplant recipients (SOTr) continues to be under investigation. Timely control of the cytokine release storm…
  • 2021 American Transplant Congress

    Perioperative Anidulafungin Combined with Triazole Prophylaxis for the Prevention of Early Invasive Candidiasis in Lung Transplant Recipients

    E. Sartain1, K. Schoeppler1, B. Crowther1, J. B. Smith2, M. Abidi3, T. J. Grazia4, M. Steele2, T. Gleason2, K. Porter2, A. Gray2

    1University of Colorado Skaggs School of Pharmacy, Aurora, CO, 2Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, 3Division of Infectious Disease, University of Colorado, Denver, CO, 4Baylor University Medical Center, Dallas, TX

    *Purpose: Invasive candidiasis (IC) is a substantial cause of morbidity and mortality in lung transplant recipients (LTRs). Post-operative factors, such as prolonged hospital stay, central…
  • 2021 American Transplant Congress

    Relationship Between Diabetes Mellitus and Covid-19 Prognosis in Kidney Transplant Patients

    D. D. de Lucena, I. A. de Brito, M. P. Cristelli, J. O. Medina-Pestana, H. Tedesco-Silva, É. B. Rangel

    Department of Medicine, Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil

    *Purpose: A high number of comorbidities associated with the severity of the disease caused by SARS-CoV-2 (COVID-19) has been reported, such as systemic arterial hypertension…
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