Am J Transplant, Volume 21, Suppl 3 Archives - Page 79 of 139 - ATC Abstracts

2021 American Transplant Congress
Donor Derived Cell Free Dna: Teasing Out the Optimal Threshold for Antibody Mediated Rejection
M. Mattu¹, H. Murad¹, M. Merzkani¹, A. Malone¹, R. Delos Santos¹, M. Wang², B. Wang², S. Chang², T. Alhamad¹
¹Department of Medicine, Washington University in St Louis, St Louis, MO, ²Washington University in St Louis, St Louis, MO
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) assay is a putative noninvasive marker for renal allograft rejection and other etiologies of injury such as BK nephropathy. The…
2021 American Transplant Congress
Belatacept Conversion in Proteinuric Renal Transplant Recipients: An Interventional Multi-Center Trial
O. Efe¹, A. Al Jurdi¹, D. Wojciechowski², K. Safa¹, H. Gilligan¹, A. Chandraker³, J. Azzi³, A. Weins³, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²UT Southwestern Medical Center, Dallas, TX, ³Brigham and Women’s Hospital, Boston, MA
*Purpose: Proteinuria develops in about 30% of kidney transplant recipients and is a strong predictor of graft loss. ACEis/ARBs can reduce proteinuria but are frequently…
2021 American Transplant Congress
The Importance of Persistent and Recurrent T Cell Mediated Rejection in Tacrolimus Treated Renal Transplant Recipients
C. Rampersad¹, I. W. Gibson², D. N. Rush¹, D. Pochinco³, P. E. Birk⁴, A. Goldberg⁴, T. Blydt-Hansen⁵, M. Karpinski¹, J. Shaw¹, J. Ho¹, P. W. Nickerson¹, C. Wiebe¹
¹Department of Medicine, University of Manitoba, Winnipeg, MB, Canada, ²Department of Pathology, University of Manitoba, Winnipeg, MB, Canada, ³Shared Health Services Manitoba, Winnipeg, MB, Canada, ⁴Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada, ⁵Department of Pediatrics, University of British Columbia, Winnipeg, MB, Canada
*Purpose: Optimal follow-up after treatment for T-cell mediated rejection (TCMR) is not well-established. We sought to identify the prevalence and clinical associations of repeated TCMR…
2021 American Transplant Congress
A Significantly Shorter Waiting Time to Subsequent Kidney Transplant After Liver Transplant by Using Safety Net Policy
P. Homkrailas, S. Bunnapradist
Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: In August 2017, a new simultaneous liver-kidney transplant (SLK) allocation policy and medical eligibility criteria were introduced. These criteria aim to avoid dual organ…
2021 American Transplant Congress
Dynamics of IgG Subclass as a Mechanism of Desensitization Using Rituximab for Presensitized Patients Undergoing Living Related Liver Transplantation
H. Egawa¹, K. Ide², T. Ishizuka³, H. Ohdan⁴, Y. Kotera¹, T. Kato¹, A. Ohmori¹, Y. Hirata¹, G. Shibuya¹, S. Yamashita¹, S. Ariizumi¹
¹Tokyo Women's Medical University, Tokyo, Japan, ²Surgery, Hiroshima University, Hiroshima, Japan, ³Clinical Laboratory, Tokyo Women's Medical University, Tokyo, Japan, ⁴Hiroshima University, Hiroshima, Japan
*Purpose: Although impact of preformed HLA-related donor specific antibody (DSA) and necessity of desensitization in liver transplantation (LT) has been recognized, mechanisms of desensitization in…
2021 American Transplant Congress
Pilot Evaluation of Prognosis After Liver Transplantation in Patients with a History of Hepatocellular Carcinoma and Pd-1 Inhibition
M. Chen¹, Z. Chen¹, X. Lin²
¹First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²the Eastern Hospital of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: The successful applications of programmed death protein-1 (PD-1) inhibitors in cancer therapy has led to an expanding use of immunotherapy in oncolog Liver transplantation…
2021 American Transplant Congress
Update on Domino Liver Transplants – A Registry Report
R. Gruessner, J. Renz, A. Gruessner
SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: The ongoing shortage of livers in the setting of a growing waiting list remains a challenge in transplantation. First introduced in 1996, domino liver…
2021 American Transplant Congress
Time-averaged Oxygen Saturation During Donor Agonal Phase is Associated with Post-transplant Hepatic Graft Survival
K. C. Eddinger¹, E. M. Sonnenberg¹, A. Kayastha², N. Mahmud³, D. E. Schaubel², P. L. Abt¹
¹Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, ²Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA
*Purpose: Livers harvested from donors after cardiac death (DCD) are subjected to a period of relative warm ischemia during the agonal phase. There have been…
2021 American Transplant Congress
Impact of Liver Acuity Circles on Timing of Donor Procurements
R. Radhakrishnan, D. Goldberg
University of Miami, Miami, FL
*Purpose: The Acuity Circles (AC) policy in liver transplantation led to broader organ sharing, whereby many organ procurement organization (OPOs) had to coordinate organ offers…
2021 American Transplant Congress
Peripheral Lymphocyte Profiling and Increased Risk of EBV Infection in Pediatric Liver Transplant Recipients
V. M. Novara Gennuso¹, T. Miloh²
¹Pediatrics, Miller School of Medicine- University of Miami, Miami, FL, ²Pediatrics, Miami Transplant Institute, Miami, FL
*Purpose: Epstein-Barr virus “EBV” infection and post-transplant lymphoproliferative disorders “PTLD” are significant comorbidities in the post-transplant “PT” setting, especially in pediatrics. The synergy among T…