2021 American Transplant Congress
COVID-19 in the Kidney Transplant Waitlist Population
1Surgery, Emory University, Atlanta, GA, 2Pathology, Emory University, Atlanta, GA
*Purpose: Through banked serum samples from transplant candidates across Georgia, we characterize the prevalence, timing, and duration of SARS-CoV-2 seropositivity and investigate the impact on…2021 American Transplant Congress
Racial and Ethnic Disparities in Pediatric Kidney Transplantation – Has KAS Made a Difference?
*Purpose: Racial and ethnic minority pediatric transplant candidates have known disparities in access to kidney transplantation. The Kidney Allocation System (KAS), implemented in 2014, was…2021 American Transplant Congress
A Molecular Classifier Identifies Antibody-Mediated Rejection-Associated Changes in Lung Transplant Biopsies
*Purpose: Identifying lung transplant antibody-mediated rejection (ABMR) has been controversial. We compared gene expression in donor-specific antibody (DSA) positive vs. DSA negative lung transbronchial biopsies…2021 American Transplant Congress
Donor-Recipient BSA Matching is Prognostically Significant in Solitary and En-bloc Kidney Transplantation from Pediatric Circulatory Death Donors
Department of Surgery, University of Washington, Seattle, WA
*Purpose: The purpose of this study was to evaluate the pernicious effects of inadequate functional nephron mass in size disparate donation after cardiac death (DCD)…2021 American Transplant Congress
Treg Engagement of Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells is Required for Allograft Protection
1U Maryland, Baltimore, MD, 2Harvard U, Boston, MA
*Purpose: Sequential migration of regulatory T cells (Treg) from graft to afferent lymphatics and lymph nodes (LN) is needed for Treg suppressive function. Migration requires…2021 American Transplant Congress
Clinical and Molecular Profiling Can Help in Predicting the Response to Alemtuzumab Treatment in Kidney Transplant Recipients with Severe or Glucocorticoid-Resistant Acute Rejection
*Purpose: Alemtuzumab is an effective drug for the treatment of severe or glucocorticoid-resistant acute kidney allograft rejection (AR), but can also cause severe adverse events.…2021 American Transplant Congress
Expanding A2 to B Kidney Transplantation: Safe and Effective Use of Recipients with High Titer Antibodies
*Purpose: Minor ABO incompatible (ABOi) transplants from blood group A2 or A2B donors have increased since 2014, but virtually all centers limit recipients to having…2021 American Transplant Congress
Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality
Transplant, Washington University, Saint Louis, MO
*Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…2021 American Transplant Congress
The Metagenomic Landscape of Renal Transplant
1Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA
*Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections. Different immunosuppression regimens have been shown…2021 American Transplant Congress
Post-Transplant Idiopathic Immune Complex Glomerulonephritis
University of Wisconsin, Madison, WI
*Purpose: The appropriate treatment for post-kidney transplant immune complex glomerulonephritis (ICGN) of unknown cause is unclear.*Methods: From 01/2004 to 12/2018, 71 patients were diagnosed with…
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