2021 American Transplant Congress
Development of De Novo Antibody in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction
*Purpose: To evaluate development of de novo donor specific antibodies (dnDSA) in Renal Transplant Recipients (RTR) with immunosuppression (IS) modulation due to BK viremia (BKV)…2021 American Transplant Congress
The Impact of the Covid-19 Pandemic on Measures of Transplant Activity is Higher in Lower-Income Countries: A Multinational Survey Study
1McGill University, Montreal, QC, Canada, 2Johns Hopkins University, Baltimore, MD
*Purpose: The COVID-19 pandemic has affected the field of solid organ transplantation due to the “ramp-down” of activity during the initial months. Impact on transplant…2021 American Transplant Congress
Journey to Transplant: A Pilot Feasibility Trial of a Virtual Counseling Intervention for Patients and Their Social Support Networks to Improve Access to Kidney Transplant
*Purpose: Home counseling interventions have shown promise in increasing rates of kidney transplant, but are challenging to implement. We piloted a structured but individualized virtual…2021 American Transplant Congress
Interruption of Notch Signaling via Blockade of Delta-Like Ligand 4 Prevents Co-Stimulation Blockade Resistant Allograft Rejection
Emory University Department of Surgery, Atlanta, GA
*Purpose: Co-stimulation blockade (CoB) has emerged as a promising immunosuppression strategy with the advent of Belatacept, a novel CTLA4-Ig fusion protein that blocks CD28-mediated T…2021 American Transplant Congress
Cost-Effectiveness Analysis of Short-Duration Anti-Viral Prophylaxis for Hepatitis C Positive Donor Kidney Transplants
Virginia Commonwealth University Health System, Richmond, VA
*Purpose: Trials describing 4-12 week courses of direct-acting anti-viral drugs (DAAs) to treat hepatitis C virus (HCV) transmission from infected donors to uninfected kidney transplant…2021 American Transplant Congress
Drones and Airplanes: Modeling the Potentially Deleterious Effects of Transportation on Shipped Organs
Surgery, University of Maryland, Baltimore, MD
*Purpose: During the first shipments of human organs by drone, we identified significant differences in pressure and vibration that may adversely affect shipped organs. Liver…2021 American Transplant Congress
Disparities in Living Donor Follow-up During the COVID-19 Emergency Suspension of OPTN Follow-up Reporting Requirements
*Purpose: The OPTN temporarily suspended follow-up reporting requirements on 4/3/20 (retroactive to 3/13/20) in response to the COVID-19 crisis. We assessed the policy’s impact on…2021 American Transplant Congress
Severe Hypoxemia After Liver Transplantation in the Hepatopulmonary Syndrome
Cleveland Clinic, Cleveland, OH
*Purpose: Hepato-pulmonary syndrome (HPS) is a complication of liver disease with liver transplantation as the only curative treatment. However these patients can develop severe hypoxemia…2021 American Transplant Congress
Tacrolimus Shortage and the Rush to Convert: An Unexpected Burden on the System During the Covid-19 Pandemic?
Medical University of South Carolina, Charleston, SC
*Purpose: A national shortage of immediate release (IR) tacrolimus (FK) fully impacted our center in May 2020. The conversion process was immediately challenging during the…2021 American Transplant Congress
Murine Cytomegalovirus Induces Kidney Allograft Injury via Th17 Cells Recruited by Both Viral Antigen-Specific and Cytokine/chemokine Mediated Pathways
*Purpose: Cytomegalovirus infection in transplant recipients has been associated with renal allograft rejection and graft failure. We have previously shown that murine CMV (MCMV) infected…
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