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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Real-time Donor-derived Cell-free Dna Kinetics Indicate Decreased “Molecular Injury” During Treatment of Acute Renal Allograft Rejection

    R. Hinojosa1, K. M. Hitchman2, D. J. Ross3, R. C. Hall1, J. E. Nelson1, E. L. Kincaide1, K. Klein1, A. M. Bell3

    1Pharmacotherapy Education and Research Center | Long School of Medicine, UT Health San Antonio | University Transplant Center, University Health, San Antonio, TX, 2Long School of Medicine, UT Health San Antonio | University Transplant Center, University Health, San Antonio, TX, 3CareDx, Inc., Brisbane, CA

    *Purpose: Dd-cfDNA is a validated plasma analyte (t½~30 min) for surveillance of renal transplant (KT) rejection with limited reports characterizing response to acute allograft rejection…
  • 2021 American Transplant Congress

    Dysregulation of Immune Cell Glycolysis and Oxidative Phosphorylation Correlates with Development of Pre-liver Transplant Immune Dysfunction and Post-transplant Mortality

    G. Panayotova1, L. Jin1, A. Lemenze1, S. Simonishvili1, Y. Qin1, L. Minze2, G. Dikdan1, F. Paterno1, X. C. Li2, M. Ghobrial2, J. V. Guarrera1, K. E. Lunsford1

    1Transplant Surgery, Rutgers NJMS, Newark, NJ, 2Transplant Surgery, Houston Methodist Hospital, Houston, TX

    *Purpose: Cirrhosis-related immune dysfunction contributes to early morbidity and mortality following liver transplant (LT). We have previously identified a pre-LT biomarker panel, the immune frailty…
  • 2021 American Transplant Congress

    Trugraf Gene Expression Testing Can Discriminate Rejection in the Setting of Acute Kidney Injury

    N. Singh1, M. S. Naseer1, D. Aultman2, H. Shokouh-Amiri2, G. Zibari2

    1Nephrology, John C. McDonald Regional Transplant Center - Willis Knighton Medical Center, Shreveport, LA, 2Advanced Surgery, John C. McDonald Regional Transplant Center - Willis Knighton Medical Center, Shreveport, LA

    *Purpose: The TruGraf kidney blood gene expression test is a well-validated non-invasive biomarker to detect immune quiescence thus ruling out silent subclinical rejection in stable…
  • 2021 American Transplant Congress

    Inducing Transient Mixed Chimerism without Chimeric Transition Syndrome for Tolerance Induction After Kidney Transplantation

    K. Lee, J. Park

    Samsung Medical Center, Seoul, Korea, Republic of

    *Purpose: Immunological or operational tolerance, defined as the absence of a destructive immune response to a transplanted tissue without ongoing immunosuppression, is one strategy that…
  • 2021 American Transplant Congress

    The Perfect Candidate? The Stanford Integrated Psychosocial Assessment for Transplant

    E. J. Henricksen1, K. Stott2, S. Ilango2, Y. Moayedi3, K. Waddell4, H. I. Luikart4, J. Twiggs4, R. Lee1, B. M. Zhang5, W. Hiesinger6, K. K. Khush4, J. J. Teuteberg4

    1Transplant, Stanford Healthcare, Stanford, CA, 2Social Work, Stanford Healthcare, Stanford, CA, 3Cardiology, University Health Network, Toronto, ON, Canada, 4Cardiology, Stanford University, Stanford, CA, 5Pathology, Stanford University, Stanford, CA, 6Cardiothoracic Surgery, Stanford University, Stanford, CA

    *Purpose: The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a tool used to objectify and enhance the pre-transplant psychosocial evaluation. We sought to assess…
  • 2021 American Transplant Congress

    Practice Patterns in Pneumocystis Jirovecii Pneumonia Prophylaxis in Solid Organ and Bone Marrow Transplant Recipients

    S. Cao, K. Khalil, F. Cirrone, S. Mehta

    NYU Langone Transplant Institute, New York, NY

    *Purpose: Trimethoprim-sulfamethoxazole (TMP-SMX) is the preferred agent for pneumocystis jirovecii pneumonia (PJP) prophylaxis in solid organ transplant (SOT) and bone marrow transplant (BMT); however, adverse…
  • 2021 American Transplant Congress

    Covid-19 in a Kidney Transplant Patient Associated with Collapsing Glomerulopathy

    W. Hninn, M. Merzkani, H. Murad, A. Malone, A. Java, G. Rajashekar, R. Delos Santos, T. Alhamad

    Washington University School of Medicine, St. Louis, MO

    *Purpose: Coronavirus- 19 is a novel virus with various clinical presentations ranging from a cold to severe acute respiratory syndrome. However, little is known about…
  • 2021 American Transplant Congress

    Beta-lactam Allergies Among Solid Organ Transplant Recipients: Prevalence and Association with Transplant Admission Length of Stay

    N. N. Pettit1, V. Nguyen2, C. T. Nguyen1, A. Lew1, J. Pisano1, L. M. Potter1

    1University of Chicago Medicine, Chicago, IL, 2University of Michigan College of Pharmacy, Ann Arbor, MI

    *Purpose: Previous studies have identified that 14-27% of solid organ transplant (SOT) recipients report a beta lactam allergy (BLA). Patients with BLAs often receive less…
  • 2021 American Transplant Congress

    Cytomegalovirus Nephritis: Epidemiology and Outcomes of an Uncommon Diagnosis

    K. J. Swanson, A. Djamali, A. Ghaffar, F. Aziz, N. Garg, M. Mohamed, D. A. Mandelbrot, M. Jorgensen, S. Parajuli

    Division of Nephrology, University of Wisconsin-Madison, Madison, WI

    *Purpose: Cytomegalovirus (CMV) nephritis is an uncommon end-organ manifestation of CMV disease. Due to this, associated outcomes have not been completely elucidated.*Methods: This was a…
  • 2021 American Transplant Congress

    Clinical Outcomes and Management of Covid-19 Patients Among Kidney Transplant Recipients: A Systematic Review

    S. Ismail1, A. Babonj2, S. Al Harbi3, A. Babonj2, A. Almalki1, E. J. Murray4

    1King Khalid hospital, MNGHA, Jeddah, Saudi Arabia, 2King Abdulaziz University, Jeddah, Saudi Arabia, 3King Faisal Specialist Hospital, Jeddah, Saudi Arabia, 4Boston University School of Public Health, Boston, MA

    *Purpose: We aim to systematically review published literature and synthesize the evidence available on therapeutic interventions and clinical outcomes used in the management of COVID-19…
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