Am J Transplant, Volume 21, Suppl 3 Archives - Page 40 of 139 - ATC Abstracts

2021 American Transplant Congress
Impact Analysis of Virtual Transplant Ambulatory Pharmacist During Covid-19
L. Park, G. Waldman, J. Kim, C. Rogers, J. Clark
Massachusetts General Hospital, Boston, MA
*Purpose: During the COVID-19 pandemic, transplant centers were challenged to meet the demand for new telemedicine strategies. High-risk immunocompromised patients, such as lung transplant recipients…
2021 American Transplant Congress
Response to a Pandemic: The Fall and Rise of Kidney Transplantation in the US
S. Bisen¹, B. Boyarsky¹, W. Werbel¹, J. Snyder², J. Garonzik-Wang¹, D. Segev¹, A. Massie¹
¹JHU, Baltimore, MD, ²SRTR, Minneapolis, MN
*Purpose: During the first wave of the COVID-19 epidemic in March-April 2020, waitlist registrations and living/deceased donor kidney transplants (LDKT/DDKT) dropped substantially. A second wave…
2021 American Transplant Congress
The Initial Impact of Covid-19 on Reported Graft Failure Rates and Potential Confounding of Srtr Psrs
A. Wey¹, J. Miller¹, D. Musgrove¹, Y. Ahn¹, M. Valapour², N. Salkowski¹, M. Skeans¹, A. Massie³, R. Hirose⁴, D. Segev³, A. Israni¹, J. Snyder¹, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²Cleveland Clinic, Cleveland, OH, ³Johns Hopkins, Baltimore, MD, ⁴Univ of California, San Francisco, San Francisco, CA
*Purpose: COVID-19 could bias the Scientific Registry of Transplant Recipients (SRTR) program-specific reports (PSRs), especially if its impact varied geographically.*Methods: Recipients who received transplants from…
2021 American Transplant Congress
High Levels of Donor-Derived Cell-Free DNA Predict EGFR Decline After Kidney Transplantation
T. Alhamad¹, V. Bowers², E. Stites³, S. Anand⁴, J. S. Bromberg⁵, H. Murad¹, G. Gupta⁶, I. Moinuddin⁶, L. Bu⁷, S. Ghosh⁸, J. Zeng⁸, A. Pai⁹
¹Washington University in St. Louis, St. Louis, MO, ²Tampa General Hospital, Tampa, FL, ³University of Colorado, Aurora, CO, ⁴Intermountain Medical Center, Murray, UT, ⁵University of Maryland School of Medicine, Baltimore, MD, ⁶Virginia Commonwealth University, Richmond, VA, ⁷University of Minnesota, Minneapolis, MN, ⁸CareDx, Brisbane, CA, ⁹University of Texas McGovern Medical School, Houston, TX
*Purpose: Persistent, low-grade inflammation is associated with decline in eGFR. Cross-sectional studies have demonstrated a consistent association between circulating inflammatory markers and kidney function. Our…
2021 American Transplant Congress
The Effect of the Different Donor-Derived HLA T-Cell Epitope Targets on the Development of T Cell-Mediated Rejection After Kidney Transplantation
A. Senev, E. Van Loon, M. Emonds, M. Naesens
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: Many kidney allografts fail due to rejections caused by the donor and recipient HLA incompatibility. Recent studies have shown that HLA-DR and DQ mismatches…
2021 American Transplant Congress
A Mechanistic Evaluation to Guide the Optimal Immunosuppression Adjustment Strategy in Transplant Patients with COVID-19
V. Hall, V. Ferreira, D. Kumar, A. Humar
UHN, Toronto, ON, Canada
*Purpose: The optimal management of immunosuppression in transplant patients infected with COVID-19 is unknown. Reduction in calcineurin inhibitors or antimetabolite doses is often performed in…
2021 American Transplant Congress
LTβR Engagement Regulates Treg Migration, Stability and Suppressor Function
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, M. W. Shirkey¹, J. Iyyathurai¹, R. Lakhan¹, R. Abdi², J. Bromberg¹
¹U Maryland, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Regulatory T cell (Treg) lymphatic migration and maintenance of transcription factor Foxp3 expression are required for suppressor function and allograft protection. Treg stimulate lymphotoxin…
2021 American Transplant Congress
Evaluation of a Weight-Based Mycophenolate Mofetil Dosing Protocol for Kidney Transplant Maintenance Immunosuppression
M. Mahoney¹, E. Kincaide¹, J. Nelson¹, K. Klein¹, R. Hall¹, S. Bhayana²
¹University Health, San Antonio, Department of Pharmacotherapy and Pharmacy Services, The University of Texas at Austin, Pharmacotherapy Division, College of Pharmacy, San Antonio, TX, ²University Transplant Center, University Health, San Antonio, Department of Nephrology, The University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: To evaluate the safety and efficacy of a weight-based mycophenolate mofetil (MMF) dosing protocol in adult kidney transplant recipients (KTR).*Methods: This single-center retrospective study…
2021 American Transplant Congress
The Pediatric National Liver Review Board: What Happens to Waitlist Registrations with Denied Exception Forms?
J. Foutz¹, C. Martinez¹, A. Henderson¹, E. K. Hsu², E. R. Perito³, J. Heimbach⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF, San Francisco, CA, ⁴Mayo Clinic, Rochester, MN
*Purpose: On 5/14/19, the exceptions review process for pediatric liver transplant (LT) candidates was changed from 11 Regional Review Boards to one National Pediatric Liver…
2021 American Transplant Congress
Covid-19 Incidence Was Initially Associated with Posttransplant Kidney Graft Failure
A. Wey¹, J. Miller¹, D. Musgrove¹, N. Salkowski¹, M. Tabaka¹, R. Hirose², A. Massie³, D. Segev³, A. Israni¹, J. Snyder¹, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²Univ of San Francisco, San Francisco, CA, ³Johns Hopkins, Baltimore, MD
*Purpose: To better understand the effect of COVID-19 on kidney posttransplant outcomes, we estimated the association of county-level COVID-19 incidence with kidney posttransplant graft failure.*Methods:…