ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Hepatic Ferroptosis in Cold Stress and Warm Ischemia-reperfusion: A Novel Therapeutic Target in Liver Transplantation

    H. Kojima1, H. Hirao1, K. Kadono1, T. Ito1, K. J. Dery1, S. Kageyama2, K. Nakamura3, F. M. Kaldas1, D. G. Farmer1, J. W. Kupiec-Weglinski1

    1UCLA Medical Center, Los Angeles, CA, 2Kyoto University, Kyoto, Japan, 3Nishi-Kobe Medical Center, Kyoto, Japan

    *Purpose: Ferroptosis, a newly discovered programmed cell death platform, due to iron-dependent accumulation of lipid peroxides, has been reported to aggravate ischemia-reperfusion (IR) injury in…
  • 2021 American Transplant Congress

    Glycogen Synthase Kinase 3 Beta Regulates Distinctive Macrophage Subsets in the Activation and Resolution of Liver Ischemia Reperfusion Injury

    H. Zhang1, M. Ni2, J. Zhang1, H. Wang2, R. Busuttil1, J. Kupiec-Weglinski1, Y. Zhai1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Glycogen synthase kinase 3β (Gsk3β) differentially regulates pro- and anti-inflammatory programs in macrophages upon TLR stimulations. We have documented in a murine liver partial…
  • 2021 American Transplant Congress

    Comparative Proteomics Analysis Identifies the Biomarker of Ischemia-Reperfusion Injury During Liver Transplantation

    M. Chen1, L. Xiaohong2, H. Xitao1, J. Weiqiang1

    1Transplant Center, Sun Yat-sen University, Guangzhou, China, 2Sun Yat-sen University, Guangzhou, China

    *Purpose: To a large extent the success of liver transplantation depends on quality of allografts. The molecular basis of the susceptibility of different liver allografts…
  • 2021 American Transplant Congress

    Incidence of Pancreatic Exocrine Insufficiency in Patients Undergoing Liver Transplantation

    J. Klein1, M. Rangel1, I. Ifearulundu1, Y. Gely1, Z. Spigel2, S. Janardhan3, M. Hertl1, E. Chan1

    1Surgery, Rush University Medical Center, Chicago, IL, 2Surgery, Allegheny Health Network, Pittsburgh, PA, 3Hepatology, Rush University Medical Center, Chicago, IL

    *Purpose: The purpose of this study was to determine the incidence of Pancreatic Exocrine Insufficiency (PEI) in patients undergoing liver transplantation. Furthermore, patient-specific risk factors…
  • 2021 American Transplant Congress

    The Role of the B2 Microglobulin Trend in Patients with Delayed Graft Function After Kidney Transplant

    A. Perez-Gutierrez, P. J. Bachul, B. Juengel, P. Witkowski, D. DiSabato, R. Barth, J. Fung, Y. Becker

    Surgery, University of Chicago, Chicago, IL

    *Purpose: Delayed graft function (DGF) is associated with worse short and long-term outcomes after kidney transplantation. There is a lack of biomarkers to predict outcomes…
  • 2021 American Transplant Congress

    Identification and Validation of a Prognostic Index for Renal Allograft Survival Based on the Geo Database

    X. Zhang, Z. Wang, Z. Han, J. Tao, X. Ju, R. Tan, M. Gu

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China

    *Purpose: Chronic allograft injury (CAI) following kidney transplantation is still a threat to the allograft long-term survival. This study was designed to explore and analyze…
  • 2021 American Transplant Congress

    The Lived Experience of Older Adult Kidney Transplant Recipients: Reflections on Embodied Selfhood in Later Life

    L. Kimberly

    New York University Langone Health, New York, NY

    *Purpose: Although the number of older adults who might benefit from kidney transplantation continues to increase in the United states, little is known about older…
  • 2021 American Transplant Congress

    Geographic Variation in Candidate Listing Behavior Under the New Heart Allocation Policy

    G. Ran1, K. Chung1, A. S. Anderson2, R. Gibbons3, N. Narang4, M. Churpek5, W. F. Parker1

    1Pritzker School of Medicine, University of Chicago, Chicago, IL, 2Department of Medicine, University of Texas San Antonio, San Antoion, TX, 3Department of Medicine, University of Chicago, Chicago, IL, 4Department of Medicine, University of Illinois-Chicago, Chicago, IL, 5Department of Medicine, University of Wisconsin, Madison, WI

    *Purpose: Describe and explain variations in listing practice among U.S. transplant centers in response to the new allocation policy.*Methods: We performed an observational cohort study…
  • 2021 American Transplant Congress

    Clinical Characteristics and Outcomes of Aspergillus Infections in Intestinal Transplant Patients: Retrospective Cohort Study

    A. Fernandez, M. Romero, Y. Natori, J. Camargo, S. Anjan, R. Vianna, J. Simkins

    Miami Transplant Institute, Jackson Health System, Miami, FL

    *Purpose: Aspergillus infection is the most common mold infection in solid organ transplant recipients and its consequences can be fatal. Data in intestinal transplants (ITx)…
  • 2021 American Transplant Congress

    COVID-19 in Kidney Transplant Recipients in the Southeastern United States: A Single Center Experience

    K. R. Kumm, S. H. Shawar, R. C. Forbes, B. P. Concepcion

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19, has emerged as a viral pandemic and brought unprecedented challenges worldwide on…
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