ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    How Long is the Wait Worthwhile: Cost-Effectiveness of Accepting a Kidney from a Donor with Apolipoprotein L1 High-Risk Genotype

    K. Lentine1, D. Brennan2, M. Wang3, M. Schnitzler4, H. Xiao4, D. Axelrod5, J. Snyder6, K. Lentine4

    1Saint Louis University, St. Louis, MO, 2Johns Hopkins, Baltimore, MD, 3Washington Univ, Saint Louis, MO, 4Saint Louis Univ, Saint Louis, MO, 5Univ of Iowa, Iowa City, IA, 6SRTR, Minneapolis, MN

    *Purpose: The Apolipoprotein L1 (APOL1) Long-Term Outcomes (APOLLO) study is underway to define the impact of kidney donor renal risk variants (RRVs) on the survival…
  • 2021 American Transplant Congress

    Acute Dialysis, Mortality and Renal Failure After Heart Alone Transplant by Egfr and Dialysis Requirement in the United States

    M. Aljuhani1, T. Alexy1, S. Jackson2, C. Martin1, R. Kandaswamy3, S. Riad1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Complex Care Analytics, Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: We examined the early acute dialysis, 90-day mortality and one-year ESRD among OHT recipients by eGFR and dialysis requirement before transplantation.*Methods: Utilizing the SRTR…
  • 2021 American Transplant Congress

    Impact of High-Risk EBV Discordance Status on Survival Outcomes in Kidney Transplant Recipients: A Multivariable Analysis

    A. Dinesh1, S. Jackson2, T. L. Pruett1, S. Riad3

    1Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, 2Biostatistics, Analytics Consulting Services- Solid Organ Transplant, M Health Fairview, Minneapolis, MN, 3Department of Medicine, University of Minnesota, Minneapolis, MN

    *Purpose: High-risk EBV discordance has been linked to Post-Transplant Lymphoproliferative Disorder (PTLD) after kidney transplantation; however, the impact on recipient and graft survival is under-reported.…
  • 2021 American Transplant Congress

    Improved Outcomes Over Time of Extended Criteria Donor Grafts for Acute-on-chronic Liver Failure

    T. Kitajima, T. Ivanics, D. Moonka, T. Shamaa, A. Mohamed, K. Delvecchio, K. Collins, M. Rizzari, A. Yoshida, M. Abouljoud, S. Nagai

    Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI

    *Purpose: Given the high waitlist mortality of patients with acute-on-chronic liver failure (ACLF), liver transplant (LT) with an extended criteria donor (ECD) can be considered.…
  • 2021 American Transplant Congress

    Early Outcome of Heart-Kidney Transplantation in the Current Heart Allocation System in the United States

    S. Rao1, A. Doyle1, D. Brennan2, S. Constantinescu3

    1University of Virginia, Charlottesville, VA, 2Johns Hopkins Medical Institute, Baltimore, MD, 3Lewis Katz School of Medicine at Temple University, Philadelphia, PA

    *Purpose: In the United States, heart allograft allocation is a primary determinant for heart-kidney transplantation (HKT). We analyzed the OPTN dataset and compared the outcomes…
  • 2021 American Transplant Congress

    Systematic Implementation of Alcohol Screening Program Using Urine Ethyl Glucuronide Can Identify Post-transplant Alcohol Use and Aid Return to Sobriety in Liver Transplant Recipients

    N. Lim1, T. Leventhal1, M. Thomson1, M. Hassan1, J. Thompson1, S. Chinnakotla2, V. Kirchner2, T. Pruett1, R. Kandaswamy2, V. Humphreville2, A. Adams2, J. Lake1

    1Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, 2Division of Transplantation, University of Minnesota, Minneapolis, MN

    *Purpose: Rates of liver transplantation (LT) for alcohol-related liver disease (ALD) are increasing, particularly in patients with acute alcoholic hepatitis. Post-LT alcohol (ETOH) use has…
  • 2021 American Transplant Congress

    Impact of Lung Allocation Score Cohort Update

    M. Skeans1, A. Wey1, E. Lease2, C. Lehr3, M. Valapour3

    1SRTR, Minneapolis, MN, 2Univ of Washington, Seattle, WA, 3Cleveland Clinic, Cleveland, OH

    *Purpose: The lung allocation score (LAS) was last revised in February, 2015, based on waitlist (WL) and posttransplant (PT) survival model cohorts from 2006-2008 and…
  • 2021 American Transplant Congress

    Utility of Non-Invasive Rejection Biomarkers to Guide Immunomodulation in Kidney Transplant Patients with Active Covid-19 Infection

    J. Christensen, G. Gupta, A. Bryson, S. Paluri, R. Thompson, S. Sterling, N. Vissichelli, P. Kimball, D. Kumar

    VCUHealth, Richmond, VA

    *Purpose: Treatment of Coronavirus Disease 2019 (COVID-19) infection in organ transplant recipients has involved reduction of immunosuppression (IS). It is plausible that the cytokine release…
  • 2021 American Transplant Congress

    Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, M. Sugimoto2, O. Konno1, I. Akashi3, M. Okihara1, Y. Kihara1, T. Ueno1

    1Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, 3Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2021 American Transplant Congress

    Mortality in Organ Transplant Recipients with Covid-19 Compared to Non-transplant or Waitlisted Patients: A Meta-analysis

    A. H. Lerner, E. Klein, D. Farmakiotis

    Rhode Island Hospital/Brown University, Providence, RI

    *Purpose: Organ transplant recipients (OTR) are considered at high risk for adverse outcomes from COVID-19. However, mortality rates range from 30%. Some studies found that…
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