ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Donor-Recipient BSA Matching is Prognostically Significant in Solitary and En-bloc Kidney Transplantation from Pediatric Circulatory Death Donors

    C. J. Little, A. A. Dick, J. D. Perkins, J. D. Reyes

    Department of Surgery, University of Washington, Seattle, WA

    *Purpose: The purpose of this study was to evaluate the pernicious effects of inadequate functional nephron mass in size disparate donation after cardiac death (DCD)…
  • 2021 American Transplant Congress

    Treg Engagement of Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells is Required for Allograft Protection

    V. Saxena1, W. Piao1, L. Li1, Y. Xiong1, M. W. Shirkey1, J. Iyyathurai1, R. Lakhan1, R. Abdi2, J. Bromberg1

    1U Maryland, Baltimore, MD, 2Harvard U, Boston, MA

    *Purpose: Sequential migration of regulatory T cells (Treg) from graft to afferent lymphatics and lymph nodes (LN) is needed for Treg suppressive function. Migration requires…
  • 2021 American Transplant Congress

    Clinical and Molecular Profiling Can Help in Predicting the Response to Alemtuzumab Treatment in Kidney Transplant Recipients with Severe or Glucocorticoid-Resistant Acute Rejection

    D. M. Peelen1, M. van der Zwan1, M. C. Clahsen-van Groningen2, D. A. Mustafa2, C. C. Baan1, D. A. Hesselink1

    1Internal Medicine - Nephrology & Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Pathology, Erasmus MC, Rotterdam, Netherlands

    *Purpose: Alemtuzumab is an effective drug for the treatment of severe or glucocorticoid-resistant acute kidney allograft rejection (AR), but can also cause severe adverse events.…
  • 2021 American Transplant Congress

    Expanding A2 to B Kidney Transplantation: Safe and Effective Use of Recipients with High Titer Antibodies

    A. Gilbert1, S. Radomski2, J. Verbesey1, J. Vucci1, M. Cooper1

    1Medstar Georgetown Transplant Institute, Washington, DC, 2Department of Surgery, Johns Hopkins Medical Center, Baltimore, MD

    *Purpose: Minor ABO incompatible (ABOi) transplants from blood group A2 or A2B donors have increased since 2014, but virtually all centers limit recipients to having…
  • 2021 American Transplant Congress

    Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality

    M. A. Merzkani, H. Murad, A. Pottebaum, A. Java, A. Malone, J. Schilling, A. Itoh, R. Delos Santos, T. Alhamad

    Transplant, Washington University, Saint Louis, MO

    *Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…
  • 2021 American Transplant Congress

    The Metagenomic Landscape of Renal Transplant

    A. Johnson1, G. Karadkhele2, C. Larsen2

    1Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections. Different immunosuppression regimens have been shown…
  • 2021 American Transplant Congress

    Post-Transplant Idiopathic Immune Complex Glomerulonephritis

    F. Aziz, T. Singh, N. Garg, D. Mandelbrot

    University of Wisconsin, Madison, WI

    *Purpose: The appropriate treatment for post-kidney transplant immune complex glomerulonephritis (ICGN) of unknown cause is unclear.*Methods: From 01/2004 to 12/2018, 71 patients were diagnosed with…
  • 2021 American Transplant Congress

    Liver Dysfunction Following Lung Transplantation

    E. J. Hyzny1, E. G. Chan1, J. P. Ryan1, T. Harano1, M. R. Morrell2, P. G. Sanchez1

    1Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: To describe the incidence and risk factors for postoperative hepatic dysfunction (POHD) following lung transplantation (LT) and long-term outcomes for these patients.*Methods: We performed…
  • 2021 American Transplant Congress

    Clinical Correlation of Frailty Measures and Evaluation of Complementary Molecular Frailty Biomarker Candidates in a Prospective National Cohort of Liver Transplant Candidates

    S. Cremen1, M. Robinson2, T. Gallagher1

    1Department of Hepatobiliary and Transplant Surgery, St Vincent's University Hospital, Dublin, Ireland, 2Department of Biology, Maynooth University, Kildare, Ireland

    *Purpose: Frailty is a clinical condition characterized by a loss of physiologic reserve and increased susceptibility to stressors. Molecular frailty biomarkers may reflect the dysregulation…
  • 2021 American Transplant Congress

    Covid-19 Impact of the Pandemic Surge on Patients Waiting for Renal Transplantation at a Single New York City Transplant Center

    G. Boyd, D. Tsapepas, R. Bonifacio, L. Brinkers, C. Brennan, A. Chang, M. Dalangin, L. Lowe, J. K. Mendoza, J. V. Mendoza, C. McNulty, M. Morris, M. Muttiah, K. Nickason, L. Ratner

    Transplant, NYP - Columbia University Medical Center, New York, NY

    *Purpose: There was a critical need to understand the impact that the COVID-19 pandemic had on our patients awaiting transplantation, including infection rates, morbidity, mortality,…
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