Am J Transplant, Volume 21, Suppl 3 Archives - Page 14 of 139 - ATC Abstracts

2021 American Transplant Congress
Hla-dq Epitope Mismatch Predicts De Novo Donor-Specific Antibody Formation and Acute Cellular Rejection After Living Donor Liver Transplantation
K. Ono, K. Ide, Y. Tanaka, M. Ohira, H. Tahara, N. Tanimine, S. Akimoto, Y. Imaoka, K. Sato, H. Yamane, N. Tsukiyama, R. Ide, T. Mochizuki, H. Ohdan
Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health S, Hiroshima University, Hiroshima City, Japan
*Purpose: Epitope mismatch (MM) effect on living donor liver transplantation (LDLT) has not been studied in detail. This study aimed to investigate the role of…
2021 American Transplant Congress
Analysis of Single Cell RNA Sequencing Data to Define Biomarkers of Human Liver Immune Tolerance
B. Rocque¹, A. Barbetta¹, P. Singh¹, C. Goldbeck¹, D. G. Helou², E. Loh³, N. Ung⁴, J. S. Lee⁴, O. Akbari², J. Emamaullee¹
¹Surgery, University of Southern California Keck School of Medicine, Los Angeles, CA, ²Molecular Microbiology and Immunology, University of Southern California, Los Angeles, CA, ³Norris Medical Library, University of Southern California Keck School of Medicine, Los Angeles, CA, ⁴Ellison Institute, University of Southern California, Los Angeles, CA
*Purpose: The liver is unique in its ability to maintain immune homeostasis and promote operational tolerance following solid organ transplantation. Single-cell RNA sequencing (scRNA seq)…
2021 American Transplant Congress
Precision Medicine in Renal Transplantation: T-cell Repertoire Sequencing to Define Donor-specific Clones for Post-transplant Monitoring
K. R. Sherwood¹, P. Wong¹, F. Fenninger¹, V. Wu¹, J. Beckrud², D. P. Cina³, L. Allan², J. Lan², P. A. Keown²
¹University of British Columbia, Vancouver, BC, Canada, ²Vancouver General Hospital, Vancouver, BC, Canada, ³Urologic Sciences, Vancouver General Hospital, Vancouver, BC, Canada
*Purpose: Measuring donor-specific clonal responses offers a precise, sensitive and specific biomarker of immune recognition and activation. Combining deep immunophenotyping (DI) and T-cell receptor (TCR)…
2021 American Transplant Congress
Medical Costs in the Year Following Kidney Transplantation: Relationships with Renal Function and Graft Failure
M. Cooper¹, M. A. Schnitzler², C. Nilubol¹, W. Wang³, X. Zhu³, J. Wu³, R. J. Nordyke⁴
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Saint Louis University, St. Louis, MO, ³Genesis Research, Hoboken, NJ, ⁴Angion Biomedica, San Francisco, CA
*Purpose: We describe relationships between total medical costs in the first year following kidney transplant with overall renal function as measured by: 1) estimated glomerular…
2021 American Transplant Congress
Outcomes of Lung Transplantation with Multi Drug Resistant Colonized Grafts, Retrospective Cohort Study in a Tertiary Care Hospital
N. Al-Ashi
Pharmacy, King Fahad Specialist Hospital -Dammam, Khobar, Saudi Arabia
*Purpose: Infections are the primary cause of morbidity and mortality after solid organ transplantation. Due to high incidence of lung graft colonization with multi drug…
2021 American Transplant Congress
Observational Study of the Clinical Characteristics and Short-term Outcomes of Kidney Transplant Recipients Diagnosed with Coronavirus-19 Infection (sars-cov2) Requiring Hospitalization in New Orleans
S. Giusti¹, S. Chazin², P. Vaitla³, K. Atiemo⁴, M. Atari¹, A. Paramesh⁴, H. Jeon⁴, A. Vijay⁴, A. Torres⁵, M. Killackey⁴, R. Thimmisetty⁶, J. Garces⁶
¹Tulane University Section of Nephrology & Hypertension, New Orleans, LA, ²Tulane University School of Medicine, New Orleans, LA, ³University of Mississippi Medical Center, Jackson, MS, ⁴Tulane Transplant Institute, New Orleans, LA, ⁵Ochsner Medical Center, New Orleans, LA, ⁶Ochsner Multi-Organ Transplant Institute, New Orleans, LA
*Purpose: Kidney transplant recipients are at increased risk of severe disease and death caused by Coronavirus-19 infection. The role of immunosuppressive medications in the clinical…
2021 American Transplant Congress
Seroprevalence of SARS-CoV-2 Antibodies in Transplant Recipients in a Croatian Transplant Center
A. Mrzljak¹, Z. Jurekovic¹, J. Pavicic Saric², L. Antolasic³, L. Milasincic³, I. Tabain³, T. Vilibic Cavlek³
¹Department of Internal Medicine, Merkur University Hospital, Zagreb, Croatia, ²Department of Anesthesiology, Merkur University Hospital, Zagreb, Croatia, ³Department of Microbiology, Croatian Institute of Public Health, Zagreb, Croatia
*Purpose: In Croatia, the first case of coronavirus disease (COVID-19) has been reported on 25 February 2020; however, the COVID-19 seroprevalence in the liver (LTR)…
2021 American Transplant Congress
Delayed Valganciclovir Initiation and the Incidence of Cytomegalovirus Infection in Liver Transplant Recipients
S. Shaikh, P. Kawewat-Ho, Y. Genyk, L. Sher, J. Kahn, L. Rivera
Keck Medical Center of USC, Los Angeles, CA
*Purpose: Opportunistic infections remain a significant burden after liver transplantation, particularly cytomegalovirus (CMV) infection. With the use of valganciclovir (VGCV), the incidence of CMV infection…
2021 American Transplant Congress
Does High-Risk CMV Discordance Affect Elderly Kidney Transplant Recipient Survival? A Multivariable Analysis
A. Dinesh¹, S. Jackson², S. Riad³, T. L. Pruett¹
¹Division of Transplantation, Department of Surgery, University of Minnesota, Minneapolis, MN, ²Biostatistics, Analytics Consulting Services- Solid Organ Transplant, M Health Fairview, Minneapolis, MN, ³Department of Medicine, University of Minnesota, Minneapolis, MN
*Purpose: High-risk CMV discordance (R-/D+) has often been linked to deleterious outcomes after kidney transplantation. The elderly transplant population is more susceptible to CMV infections…
2021 American Transplant Congress
An Unusual Viral Tropism in a Solid Organ Transplant Recipient
P. Singh, A. Bentall, C. Langstraat, A. Swanson, P. Deziel, Y. Huang, R. Razonable
Mayo Clinic, Rochester, MN
*Purpose: Cytomegalovirus (CMV) tissue-invasive disease occurs in higher proportion in CMV-mismatched kidney transplant recipients (KTxR) with no pre-existing immunity and those who are markedly immunologically-impaired.…