ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Is There a Role for Donor-Specific Antibody Testing in Simultaneous Liver-Kidney Transplantation? A Single Center Analysis of Outcomes

    A. Das, A. Barbetta, D. Remulla, C. Goldbeck, T. Maw, J. Kim

    University of Southern California, Los Angeles, CA

    *Purpose: Simultaneous liver-kidney transplantation (SLKT) has grown exponentially since its conception in the 1960’s. The role for donor specific antibody (DSA) testing in SLKT is…
  • 2021 American Transplant Congress

    Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury in a Renal Specific Manner

    C. S. O'Brien, P. Hernandez, Z. Wang, G. Ge, W. Hancock, M. H. Levine

    Surgery, University of Pennsylvania, Philadelphia, PA

    *Purpose: Renal Ischemia Reperfusion Injury (IRI) is a major contributor to delayed graft function (DGF) in kidney transplantation. Previously, we have shown lower rates of…
  • 2021 American Transplant Congress

    Associations of Lack of Insurance and Other Sociodemographic Traits with Deficiencies in Follow-Up After Living Kidney Donation

    K. Lentine1, R. Hays2, N. Lam3, A. Tietjen4, A. Muiru5, H. Xiao1, A. Garg6, C. Thomas7, G. McNatt7, R. Howey8, U. Lebron-Banks9, M. Cooper10, M. Conboy11, B. Kasiske11

    1Saint Louis Univ, Saint Louis, MO, 2Univ of Wisconsin, Madison, WI, 3Univ of Calgary, Calgary, AB, Canada, 4St. Barnabas, Livingston, NJ, 5Univ of California, San Francisco, San Francisco, CA, 6Western Univ, London, ON, Canada, 7Univ of Iowa, Iowa City, IA, 8Toyon Associates, Concord, CA, 9New York Presb Hosp, New York, NY, 10Medstar-Georgetown, Washington, DC, 11SRTR, Minneapolis, MN

    *Purpose: Follow-up after living kidney donation in the United States has improved with recent policy mandates. We hypothesized that lack of insurance at donation may…
  • 2021 American Transplant Congress

    Psychosocial Determinants of Regimen Adherence Among Kidney Transplant Recipients

    A. Balakrishnan, S. Bailey, D. Mroczek, M. Serper, D. P. Ladner, M. S. Wolf

    Northwestern University, Chicago, IL

    *Purpose: There is increasing evidence suggesting a high prevalence of inadequate medication adherence among kidney transplant recipients (KTRs) and its subsequent consequences on health outcomes.…
  • 2021 American Transplant Congress

    The Australian and New Zealand Living Kidney Donor Profile Index

    G. L. Irish1, S. Chadban1, N. Boudville2, S. B. Campbell3, J. Kanellis4, P. A. Clayton1

    1Australian and New Zealand Dialysis and Transplant Registry, South Australian Health and Medical Research Institute, Adelaide, Australia, 2Medical School, University of Western Australia, Perth, Australia, 3Department of Nephrology, Princess Alexandra Hospital, Brisbane, Australia, 4Department of Nephrology, Monash Health, Melbourne, Australia

    *Purpose: Risk scores may aid risk quantification and decision-making in kidney transplantation. The Living Kidney Donor Profile Index (LKDPI) was developed to choose between living…
  • 2021 American Transplant Congress

    Assessing the Prevalence of Risk Factors for Osteoporosis and Rate of Screening by Dexa Scan in Patients Referred for Liver Transplant Evaluation

    A. France1, J. Kirk2, M. Dokus2, B. Al-Judaibi2, M. Laryea2

    1Department of Internal Medicine, University of Rochester Medical Center, Rochester, NY, 2Division of Gastroenterology and Hepatology, University of Rochester Medical Center, Rochester, NY

    *Purpose: Osteoporosis (OP) and fragility fractures are well-known complications of both chronic liver disease (CLD) and transplant, with a significant increase in the prevalence of…
  • 2021 American Transplant Congress

    The Effect of Acuity Circles on Deceased Donor Transplant and Offer Rates Across Meld and Exception Statuses

    A. Wey1, S. Noreen2, S. Gentry3, N. Salkowski1, M. Cafarella2, R. Hirose4, J. Trotter5, D. Segev6, A. Israni1, J. Snyder1, B. Kasiske1

    1SRTR, Minneapolis, MN, 2UNOS, Richmond, VA, 3USNA, Annapolis, MD, 4Univ of San Francisco, San Francisco, CA, 5BSW Health, Dallas, TX, 6Johns Hopkins, Baltimore, MD

    *Purpose: Acuity circles (AC) allocation was implemented on February 4, 2020. AC significantly changed the relative priority of candidates with allocation PELD/MELD scores of 29…
  • 2021 American Transplant Congress

    Environmental Factors That Shape T-cell Alloimmunity: Role of the Microbiome

    K. Janek1, J. H. Fechner1, R. A. Daley1, K. Krautkamer1, F. Rey2, J. D. Mezrich1

    1Surgery, University of Wisconsin School of Medicine & Public Health, Madison, WI, 2Bacteriology, University of Wisconsin, Madison, WI

    *Purpose: Unlike other types of immunity, T-cell alloimmune responses to mismatched MHC proteins do not need priming by a previous exposure. While genetic differences between…
  • 2021 American Transplant Congress

    Transgenic Beta-cell Cxcl12 Expression and Stem Cell Mobilization Synergize to Suppress Type 1 Diabetes

    D. A. Alagpulinsa, A. Jajoo, M. H. Chapin II, M. C. Poznansky

    Vaccine & Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA

    *Purpose: Hematopoietic stem and progenitor cells (HSPCs) and regulatory T cells (Tregs) highly express CXCR4, the receptor for the CXCL12 chemokine. This keeps them predominantly…
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