2021 American Transplant Congress
Effects of IL-2 and/ or Anti-IL6R Therapy on Long-term Cardiac Allograft Survival in Non-Human Primates (NHPs)
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
*Purpose: Cardiac allograft tolerance in NHPs has been achieved by our group using a mixed chimerism model with allogeneic bone marrow transplant after non-myeloablative conditioning…2021 American Transplant Congress
Transgenic Overexpression of Human Ectonucleoside Triphosphate Diphosphohydrolase 1 (entpd1, Or Hcd39) in Pig to Primate Xenotransplantation Models
*Purpose: Human CD39 (hCD39) is the gene of interest in xenotransplantation due to its reported capacity to prevent platelet aggregation by metabolizing extracellular ATP to…2021 American Transplant Congress
Tubastatin-a Mediated Protection from Liver Injury is Preserved in a Lymphocyte Deficient Model
1University of Pennsylvania, Philadelphia, PA, 2University of Illinois at Chicago, Chicago, IL
*Purpose: Liver Ischemia reperfusion injury (IRI) and Acetaminophen (APAP) toxicity are important causes of acute liver failure in the United States, that lack effective therapy.…2021 American Transplant Congress
General Public Attitude Toward Vascularized Composite Allografts (VCA) Donation?
*Purpose: To analyze factors associated with affirmative authorization for VCA donation from public opinion.*Methods: KnowledgePanel is the largest online panel that relies on probability-based sampling…2021 American Transplant Congress
Combined Donor Derived Cell Free DNA (AlloSure) and Peripheral Immune Cell Gene Expression (AlloMap) Testing for the Diagnosis of Rejection in Kidney Transplant Recipients with De Novo Donor Specific Antibodies
University of Wisconsin, Madison, WI
*Purpose: Combined donor-derived cell-free DNA (dd-cfDNA, AlloSure) and peripheral immune cell gene expression (AlloMap) may increase the predictive value of de novo DSA (dnDSA) for…2021 American Transplant Congress
Immunosuppression is Not Associated with High-risk Immunologic Parameters in Transplant Recipients with the Sars-cov2 Virus
Medicine/Surgery, Columbia University Medical Center, New York, NY
*Purpose: The factors associated with severe COVID-19 disease in transplant patients are poorly understood. Despite concern that patients with weakened immune responses have increased risk…2021 American Transplant Congress
Tru and Sure -A Tale of Two Cities! Can Allosure Predict and Enhance Trugraf Results?
1Keck Medical Center at USC, Los Angeles, CA, 2Keck Medical Center at USC, La Canada Flt, CA
*Purpose: With the introduction of Cell free DNA(cfDNA) technology in transplantation a few years ago, and a more recent addition of genomic testing with TruGraf…2021 American Transplant Congress
Estimated GFR by Serum Myo-inositol, Valine, Creatinine, and Cystatin-c Outperforms Current CKD-epi Equations in Renal Transplant Recipients
*Purpose: Current estimated GFR (eGFR) equations using creatinine and/or cystatin C do no perform well in kidney transplant (KTx) recipients. Therefore, some large transplant programs…2021 American Transplant Congress
Solid Organ Transplant Recipients and Healthcare Burden in Covid19 Era
*Purpose: Pneumonia(PNA)- Acute inflammation of the lung parenchyma from an infection, is a frequent cause for hospitalization among Solid Organ Transplant Recipients (SOTRs), adversely effecting…2021 American Transplant Congress
Risk Factors Associated with Severe COVID19 Illness in Kidney Transplant Recipients
Hamad Medical Corporation, Doha, Qatar
*Purpose: COVID19 is an acute respiratory infection that is caused by the SARS-COV-2 that has been shown to be highly contagious and poses a significant…
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