2021 American Transplant Congress
Extracellular Vesicles from Patients with Diabetic Nephropathy Induce Endothelial Dysfunction Through Icam-1 and Vcam-1 in an In Vitro Model
*Purpose: Extracellular Vesicles (EVs) are membranous structures produced by cells which contain different cytoplasmic compounds and that have been described as potentially pathogenic elements in…2021 American Transplant Congress
CHBP Induces Stronger Immunosuppressive CD127+ M-MDSC via Erythropoietin Receptor
Urology, Zhongshan Hospital, Fudan University, Shanghai, China
*Purpose: Erythropoietin (EPO) is not only an erythropoiesis hormone, but also an immune regulatory cytokine. The receptors of EPO, (EPOR)2 and tissue protective receptor (TPR),…2021 American Transplant Congress
Anti-CD272 Antibody (6B2) Generated Foxp3+Regulatory T Cells and Suppressed Donor Specific Antibody in Murine Cardiac Transplant Model
*Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…2021 American Transplant Congress
Transforming Growth Factor-Beta Induced Myeloid-Derived Suppressor Cells Promote Transplant Immune Tolerance
*Purpose: Myeloid-derived suppressor cells (MDSCs) are a group of heterogeneous cells derived from bone marrow with immunosuppressive effect, which contribute to the establishment of transplant…2021 American Transplant Congress
The Harmful Effect of Retained Peripheral Cells During Flushing and Static Cold Storage in Rat Liver Normothermic Machine Perfusion
*Purpose: Retained donor blood in a liver graft can cause damage to resident cells that is exacerbated by static cold storage (SCS), leading to platelet…2021 American Transplant Congress
Galectin-3 Blockade Can Decrease Reperfusion Injury in Response to Ischemia in a Rat Hind Limb Transplant Model
1University of Colorado, Aurora, CO, 2University of Michigan, Ann Arbor, Ann Arbor, MI
*Purpose: Vascularized composite allograft (VCA) transplant is technically feasible and results in successful clinical outcomes. However, skin and muscle containing VCA is highly susceptible to…2021 American Transplant Congress
Remote Monitoring Using Mobile Phlebotomy and Donor-derived Cell-free DNA in Kidney Transplant Recipients During the Covid-19 Pandemic
1NYU Langone, New York, NY, 2Medical Science Liason, CareDx, Brisbane, CA
*Purpose: The rapid shift to telemedicine and remote monitoring of kidney transplant recipients (KTRs) during COVID-19 aimed to mitigate exposure risk for this vulnerable population.…2021 American Transplant Congress
Outcomes of Novel Coronavirus 2019 in Solid Organ Transplant Recipients: Yet Again, Race and Payor Status Matters
*Purpose: By the early spring of 2020, the United States has become the global epicenter of the coronavirus 2019 (COVID-19) pandemic. Little is known if…2021 American Transplant Congress
Initial Experience with TrugrafTm Gene Expression Profile and TracTm Dd-cfdna Testing in Kidney Transplant Recipients Suggests Synergy and Enhanced Management within the First Year Post-transplant and Beyond
Nephrology, Baystate Medical Center, Springfield, MA
*Purpose: Non-invasive validated rejection biomarkers are now available to monitor kidney transplant patients (KTRs). Two such biomarkers are; TruGrafTM (TG) gene expression profile validated to…2021 American Transplant Congress
Analysis of the Difference of the Monitoring Results of Tcr High Variable Area in Renal Transplant Recipients After Treatment with Different Immune Induction Schemes
The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China
*Purpose: To observe and summarize the effect of different induction schemes on the highly variable region of T-lymphocyte receptor (TCR) in living relative renal transplant…
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