ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Caspase-3 is a Predominant Regulator of Microvascular Dysfunction and Aki-ckd Transition Post Renal Ischemia-reperfusion Injury

    S. Lan, F. Migneault, J. Turgeon, M. Bourgault, M. Dieudé, N. Patey, H. Cardinal, M. Hébert

    CRCHUM, University of Montreal, Montreal, QC, Canada

    *Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor for chronic renal failure. Caspase-3, an effector responsible for apoptosis execution, is activated within tubular epithelial…
  • 2021 American Transplant Congress

    Identification and Comprehensive Validation of Prognostic Genes After Ischemic and Reperfusion Injury Across Different Donor Types in Renal Transplantation

    D. Zhang, Y. Wang, Y. Wang, X. Hu

    Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China

    *Purpose: Ischemic and reperfusion injury (IRI) remains an inevitable and major challenge for renal transplant patients. The current study aims to obtain overall insights into…
  • 2021 American Transplant Congress

    Impact of Deceased Donor Mode of Death and Kidney Donor Profile Index on Baseline Donor Derived Cell Free DNA in Kidney Transplant Recipients

    B. Chopra, A. Grazier, K. K. Sureshkumar

    Allegheny Health Network, Pittsburgh, PA

    *Purpose: Donor derived-cell free DNA (dd-cfDNA) is a novel serum biomarker available for earlier prediction of acute rejection in renal allograft. Baseline dd-cfDNA values are
  • 2021 American Transplant Congress

    Brain Natriuretic Peptide and Pedometer Activity are Most Predictive of Poor Kidney Transplant Waitlist Outcomes

    P. Manay1, P. TenEyck2, R. Kalil3, M. Sanders4, M. Swee4, G. Binns5, J. Hornikel5, D. Katz1

    1Department of Surgery, University of Iowa, Iowa City, IA, 2Institute for Clinical and Translational Science, University of Iowa, Iowa City, IA, 3Department of Medicine, University of Maryland Medical Center, Baltimore, MD, 4Department of Medicine, University of Iowa, Iowa City, IA, 5Iowa City VAMC, Iowa City, IA

    *Purpose: Tools for indicating which patients are most at risk for complications and death after transplant listing would allow for a rational approach to targeted…
  • 2021 American Transplant Congress

    GENiE in a Bottle – Renasight Testing in the Kidney Transplant Setting – A Single Center Experience

    Y. A. Qazi1, W. Mon1, N. Ioannou2, M. Smogorzewski1

    1Keck Medical Center at USC, Los Angeles, CA, 2Natera, San Carlos, CA

    *Purpose: Renasight™(Natera), a recently available genetic test provides analysis on 382 genes associated with adult-onset kidney disease, covering clinical categories (cystic, tubular, glomerular, complement-related, congenital…
  • 2021 American Transplant Congress

    Torque Teno Virus Load Predicts Allograft Rejection but Not Viral Infection After Kidney Transplantation; A Cohort Joint Modelling Study

    A. L. van Rijn1, H. F. Wunderink2, I. A. Sidorov1, C. S. de Brouwer1, A. C. Kroes1, H. Putter3, A. P. de Vries4, J. I. Rotmans4, M. C. Feltkamp1

    1Medical Microbiology, Leiden University Medical Center, Leiden, Netherlands, 2Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands, 3Medical Statistics, Leiden University Medical Center, Leiden, Netherlands, 4Internal Medicine, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: The main challenge of immunosuppressive therapy after solid organ transplantation is to find the optimal dose regimen, and prevent allograft rejection as well as…
  • 2021 American Transplant Congress

    Impact of Rejection in Pediatric and Young Adult Kidney Transplant Recipients on the Use of Mental Health Resources

    E. Ruzicka1, E. Lyons2, C. Naclerio2, A. Sikora2, K. McKinnon2, E. Blanchette2, M. Chandran2, M. Bock2, E. Christofferson2

    1Children's Hospital Colorado, Aurora, CO, 2University of Colorado, Aurora, CO

    *Purpose: Allograft rejection often results in increased hospital and medical resource utilization. Pediatric kidney transplant recipients (KTR) are at risk for psychosocial stressors, nonadherence to…
  • 2021 American Transplant Congress

    Simultaneous Heart-Liver-Kidney Transplantation Survival: National and Single-Center Outcomes

    U. A. Siddiqi1, P. S. Combs1, G. Kim2, T. Baker3, Y. Becker1, V. Jeevanandam1

    1Section of Cardiac Surgery, University of Chicago Medicine, Chicago, IL, 2Section of Cardiology, University of Chicago Medicine, Chicago, IL, 3University of Chicago Medicine, Chicago, IL

    *Purpose: Simultaneous Heart-Liver-Kidney transplantation (SHLKTx) is an incredibly rare, high-risk operation undergone by well-selected patients presenting with multi-organ failure. Our center has performed 10 of…
  • 2021 American Transplant Congress

    Outcomes in High Risk CMV Liver Transplants with Elevated MELD Scores

    S. Freedman1, K. Saunders2, T. Sparkes1, B. Masters1, M. Plazak1, K. Saharia3, D. Maluf3, B. Ravichandran2

    1University of Maryland Medical Center, Baltimore, MD, 2University of Maryland School of Pharmacy, Baltimore, MD, 3University of Maryland School of Medicine, Baltimore, MD

    *Purpose: There is inconclusive evidence on the impact of MELD score on CMV viremia after liver transplantation. Following the implementation of Share 35, liver transplant…
  • 2021 American Transplant Congress

    COVID-19 in Hospitalized Kidney Transplant Recipients: Clinical Course, Prognostic Factors and Differences Between First and Second Waves

    N. Macías, M. Rodríguez Ferrero, A. Acosta, J. Carbayo, Á. González Rojas, A. Muñoz de Morales, A. García Prieto, M. Goicoechea

    Nephrology, Hospital Gregorio Marañón, Madrid, Spain

    *Purpose: The aim was to describe the clinical course and management of SARS-CoV-2 infection in kidney transplant recipients (KTR) hospitalized with COVID-19, identify risk factors…
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