ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    A Machine Learning-Based Predictive Model for Outcome of Covid-19 in Kidney Transplant Recipients

    I. Revuelta1, F. Santos-Arteaga2, D. Di Caprio3, E. Montagud-Marrahi1, F. Cofan1, J. Torregrosa1, M. Bodro4, A. Moreno4, P. Ventura-Aguiar1, D. Cucchiari1, N. Esforzado1, G. Piñeiro1, J. Ugalde-Altamirano1, J. Campistol1, A. Alcaraz5, B. Bayès1, E. Poch1, F. Oppenheimer1, F. Diekmann1

    1Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, 2Faculty of Economics and Management, Free University of Bolzano, Bolzano, Italy, 3Department of Economics and Management, University of Trento, Trento, Italy, 4Department of Infectious Diseases, Hospital Clinic, Barcelona, Spain, 5Department of Urology, Hospital Clinic, Barcelona, Spain

    *Purpose: Health systems need tools to deal with COVID-19, especially for high-risk population,such as transplant recipients. Predictive models are necessary to improve management of patients…
  • 2021 American Transplant Congress

    Challenges and Stressors of COVID-19 Kidney and Transplant Patients: A Mixed Methods Study

    Y. A. Iraheta1, A. L. Murillo2, E. H. Wood1, S. M. Advani3, R. Pines4, A. D. Waterman1

    1UCLA David Geffen School of Medicine, Los Angeles, CA, 2Terasaki Institute, Los Angeles, CA, 3National Human Genome Research Institute (NIH), Bethesda, MD, 4Santa Barbara Cottage Hospital, Santa Barbara, CA

    *Purpose: To assess the unique needs of at-risk kidney and transplant patients and their caregivers during COVID-19, we established a telephone Listening Center enabling them…
  • 2021 American Transplant Congress

    Successful Long-Term TMA- and Rejection-Free Survival of a Kidney Xenograft With Triple Xenoantigen Knockout Plus Insertion of Multiple Human Transgenes

    T. Hirose1, D. Ma1, G. Lassiter1, H. Sasaki1, I. Rosales2, T. Coe1, C. Rickert1, R. Matheson1, R. Colvin2, W. Qin3, Y. Kan3, J. Layer3, K. Stiede3, K. Hall3, M. Youd3, W. Westlin3, M. Curtis3, J. F. Markmann1, T. Kawai1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2Pathology, Massachusetts General Hospital, Boston, MA, 3eGenesis Inc, Cambridge, MA

    *Purpose: Pigs with deletion of 3 carbohydrate xenoantigens (triple knock-out, TKO) are expected to be optimal donors for human xenotransplantation. However, anti-porcine natural antibodies of…
  • 2021 American Transplant Congress

    Transplanting Hepatitis C Infected Organs Into Uninfected Recipients: A Pharmacy Perspective

    M. L. Holt, A. James, K. Gutierrez, T. Sparkman, J. Banbury, D. Jones

    University of Alabama at Birmingham Hospital, Birmingham, AL

    *Purpose: Due to direct acting antivirals (DAAs), hepatitis C virus (HCV) positive patients are now resources for organ transplantation in HCV negative recipients. Our institution…
  • 2021 American Transplant Congress

    Does the NSQIP-Transplant Experience Demonstrate That Obese Kidney Transplant Recipients are Still at Increased Risk for Surgical Site Infections?

    H. C. Yaffe1, A. K. Belli1, J. R. Parekh2, D. L. Sudan3, N. Elias4, K. D. Conzen5, D. P. Foley6, R. Hirose7, S. M. Greenstein1

    1Surgery, Montefiore-Einstein Center for Transplantation, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, 2Surgery, University of California San Diego, San Diego, CA, 3Surgery, Division of Abdominal Transplant Surgery, Duke University Medical Center, Durham, NC, 4Surgery, Transplant Surgery Division, Massachusetts General Hospital, Boston, MA, 5Surgery, Division of Transplant Surgery, University of Colorado Hospital, Aurora, CO, 6Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, 7Surgery, University of California San Francisco, San Francisco, CA

    *Purpose: The National Surgical Quality Improvement Program for Transplant (NSQIP-T) was designed to track surgical outcomes in adult liver and kidney transplants (KTX). The Pilot…
  • 2021 American Transplant Congress

    Predicted Heart Mass Difference as a Risk Factor for Severe Primary Graft Dysfunction in the Contemporary Era of Heart Transplantation: A Report from the International Consortium on Primary Graft Dysfunction

    F. Foroutan1, L. K. Truby2, Y. Moayedi1, J. Han3, J. Guzman4, M. Farrero4, E. Baughan5, M. Farr5, H. Zafar6, J. Felius6, J. van Zyl7, D. Law8, S. Chih8, P. Angleitner9, M. Sabatino10, A. DeVore2, R. J. Miller11, L. Potena10, A. Zuckermann9, K. K. Khush3, S. A. Hall6, H. J. Ross1

    1Ted Rogers Centre for Heart Research, Toronto, ON, Canada, 2Duke University School of Medicine, Durham, NC, 3Stanford University, Stanford, CA, 4Clinic Barcelona Hospital Universitari, Barcelona, Spain, 5Columbia University Medical Center, New York, NY, 6Baylor University Medical Center, Dallas, TX, 7Dallas University Medical Center, Dallas, TX, 8University of Ottawa Heart Institute, Ottawa, ON, Canada, 9Medical University of Vienna, Vienna, Austria, 10Bologna University Hospital, Bologna, Italy, 11University of Calgary, Calgary, AB, Canada

    *Purpose: Primary Graft Dysfunction (PGD) increases early mortality after heart transplant (HT). Predicted heart mass (PHM) difference may be a risk factor for PGD. Lack…
  • 2021 American Transplant Congress

    The Intersection of Cost, Quality, and Volume in Liver Transplant

    D. Axelrod1, R. Balakrishnan1, A. Harris2, S. Hohmann2, J. Snyder3, B. Kasiske3, M. Schnitzler4, K. Lentine4

    1Univ of Iowa, Iowa City, IA, 2Vizient Inc., Irving, TX, 3SRTR, Minneapolis, MN, 4Saint Louis Univ, Saint Louis, MO

    *Purpose: As a consequence of changing allocation practices and the ongoing shortage of high-quality organs, the cost of liver transplant (LT) continues to increase throughout…
  • 2021 American Transplant Congress

    Aligning Pediatric Waiting List and Post-Transplant Outcomes with the Adult Lung Allocation Score

    M. Skeans1, A. Wey1, E. Lease2, C. Lehr3, J. Alcorn4, R. Goff4, D. Stewart4, M. Valapour3

    1SRTR, Minneapolis, MN, 2Univ of Washington, Seattle, WA, 3Cleveland Clinic, Cleveland, OH, 4UNOS, Richmond, VA

    *Purpose: Lung allocation is moving toward a continuous distribution framework (CDF), with components for waitlist (WL) urgency and post-transplant (PT) survival, as computed in LAS.…
  • 2021 American Transplant Congress

    The Microenvironment of Belatacept-Resistant Rejection

    A. Johnson, J. Zhang, C. Larsen

    Surgery, Emory University, Atlanta, GA

    *Purpose: Belatacept is a co-stimulation blockade immunosuppressant, that despite demonstrating improved long-term outcomes, has not been widely adopted, in part, due to concern over early…
  • 2021 American Transplant Congress

    Quantifying Hidden Sensitization: HLA-reactive Memory B Cells in the Spleens of Sensitized Women

    J. T. Killian1, J. A. Houp1, A. Nellore2, R. G. King3, P. M. Porrett1, F. E. Lund3

    1Department of Surgery, University of Alabama at Birmingham School of Medicine, Birmingham, AL, 2Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, 3Department of Microbiology, University of Alabama at Birmingham School of Medicine, Birmingham, AL

    *Purpose: Measurement of circulating anti-HLA antibody (anti-HLA-Ab) in transplant candidates and recipients is required for successful organ transplantation. However, serum Ab measurement alone likely underestimates…
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