Am J Transplant, Volume 20, Suppl 3 Archives - Page 79 of 223 - ATC Abstracts

2020 American Transplant Congress
Heart Transplantation Outcomes in Patients with Marfan Syndrome: A UNOS Registry Analysis
P. Genyk¹, K. Yang¹, J. Pizula¹, A. Lee¹, D. Miklin¹, S. Shah¹, S. Nuno¹, S. Hashmi¹, J. Nattiv¹, A. Kiankhooy¹, L. Grazette¹, M. Fong¹, J. Rahman¹, K. Pandya¹, A. Vaidya¹, D. Vucicevic², J. Li¹, P. Kingsford¹, P. Banankhah¹, A. Wolfson³, G. Liu¹, R. Chand⁴, E. Depasquale¹
¹Keck Medicine of USC, Los Angeles, CA, ²Newark Beth-Israel Medical Center, Newark, NJ, ³University of Arizona Sarver Heart Center, Tucson, AZ, ⁴Harbor-UCLA Medical Center, Torrance, CA
*Purpose: Marfan syndrome (MS) is an autosomal dominant connective tissue disorder due to a defect in the fibrillin-1 gene. MS patients can develop a discrete…
2020 American Transplant Congress
Bariatric Surgery for Congestive Heart Failure Patients Improves Access to Transplantation and Long-Term Survival
R. A. Choudhury¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, D. Yoeli¹, K. R. Dumon³, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Colorado Hospital, Philadelphia, PA
*Purpose: Obese patients with congestive heart failure (CHF) are often denied access to heart transplantation until they obtain significant weight loss to achieve a certain…
2020 American Transplant Congress
The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion
K. Noda¹, B. J. Philips¹, M. Velayutham², T. Harano¹, P. Reck dos Santos¹, S. Shiva², P. G. Sanchez¹
¹Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA
*Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…
2020 American Transplant Congress
Five Year Patient Important Outcomes of Treated Acute Rejections Diagnosed with Protocol and Clinical Biopsy after Pancreas Transplant Alone for Type 1 Diabetes
Y. C. Kudva, S. R. Rizvi, R. Kaur, B. H. Smith, S. Batthula, P. G. Dean, A. Kukla, W. K. Kremers, M. D. Stegall
Mayo Clinic, Rochester, MN
*Purpose: STUDY PURPOSE: Acute rejection (AR) after Pancreas Transplant alone (PTA) continues to be a significant morbidity. We compared the outcomes of PTA recipients treated…
2020 American Transplant Congress
Machine Learning Model Outperforms Linear Regression Models for 1- and 3-Year Post-Transplant Survival: Is This the Future?
R. W. Pettit¹, S. J. Corr², J. Havelka³, A. Rana¹
¹Baylor College of Medicine, Houston, TX, ²Interdisciplinary Surgical Technology and Innovation Center, Baylor College of Medicine, Houston, TX, ³InformAI, Houston, TX
*Purpose: Modeling is essential for regulatory oversight and risk stratification in clinical practice. Our hypothesis was that machine learning models would be superior to linear/logistic…
2020 American Transplant Congress
Estrogen Receptor Beta Deletion in the Vascular Endothelium is Protective in Renal Ischemia Reperfusion Injury
L. Krumeich¹, P. Hernandez¹, C. O'Brien¹, S. Concors¹, Z. Wang¹, G. Ge¹, W. Hancock², M. Levine¹
¹Hospital of University of Pennsylvania, Philadelphia, PA, ²Childrens Hospital of Philadelphia, Philadelphia, PA
*Purpose: Renal ischemia reperfusion injury (IRI) is a major contributor to early allograft dysfunction (EAD) in kidney transplantation. We previously identified lower rates of EAD…
2020 American Transplant Congress
AIPCs Home to and Engraft in the Pancreas When Injected Intravenously
J. B. Pollett¹, N. Thai²
¹Imagine Pharma, Pittsburgh, PA, ²Allegheny Health Network, Pittsburgh, PA
*Purpose: AIPCs (Activated Islet Proliferating Cells) are a recently developed cell population generated from isolated islets of mice and humans. AIPCs are over 65% CD133-,…
2020 American Transplant Congress
The Fibrinogen-Like Protein 2 Molecule Influences the Development of Thymic Regulatory T-Cells
C. Lam¹, S. Moshkelgosha¹, G. A. Levy², A. Chruscinski³, S. C. Juvet⁴
¹Latner Thoracic Surgery Research Laboratories, University Health Network, Toronto, ON, Canada, ²Multi Organ Transplant Program, University Health Network, Toronto, ON, Canada, ³Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON, Canada, ⁴Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada
*Purpose: Transplantation is the primary treatment for patients with end-stage organ failure. However, long-term outcomes are limited by immunosuppressant toxicities and chronic graft rejection. Identifying…
2020 American Transplant Congress
Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus
H. Joharji, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. Elsiesy, M. Alsebayel, H. Alashgar, M. Alquaiz, W. Alhamoudi, A. Almoshishir, A. Aljedai
King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
*Purpose: Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of HCV has shifted in the last few…
2020 American Transplant Congress
Post-Transplant Rebound and Not Baseline Anti-A Titers are Associated with Acute Antibody-Mediated Rejection in A₂– to B/O Incompatible Kidney Transplantation
V. Kumar, D. Mompoint-Williams, M. Marques, P. MacLennan, M. Mustian, J. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Decreased antigen expression among blood group A subtype 2 (A2) donor kidneys allows these organs to be considered as universal donors; under the new…