Am J Transplant, Volume 20, Suppl 3 Archives - Page 70 of 223 - ATC Abstracts

2020 American Transplant Congress
Association between Sarcopenia and Nutritional Factors in Kidney Transplant Recipients
A. Kosoku¹, J. Uchida¹, T. Ishihara², T. Iwai¹, H. Shimada¹, K. Kabei¹, S. Nishide¹, T. Naganuma¹, T. Nakatani¹
¹Urology, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Innovative and Clinical Research Promotion Center, Gifu University Hospital, Gihu, Japan
*Purpose: Malnutrition is an important risk factor for the development of sarcopenia. Several methods are used for the assessment of nutritional status including serum albumin…
2020 American Transplant Congress
Should Steatotic Livers Be Transplanted Into Pediatric Recipients?
M. MacConmara, C. Feizpour, P. Vagefi, C. Ramirez, L. DeGregorio, C. S. Hwang
UT Southwestern, Dallas, TX
*Purpose: Although steatotic livers are frequently transplanted in the adult population, they are not commonly transplanted in pediatric recipients. We questioned if the outcomes of…
2020 American Transplant Congress
Hypothermia Attenuates Renal Fibrosis after Renal Ischemia Reperfusion in Mice
D. Choi¹, D. Kim², E. Kim², J. Jeong², J. Kim¹, Y. Ham¹, Y. Chang³, K. Na¹, K. Lee¹
¹Nephrology, Chungnam National University, Daejeon, Korea, Republic of, ²Department of Medical Science, Chungnam National University, Daejeon, Korea, Republic of, ³Nephrology, Catholic University of Korea, Daejeon, Korea, Republic of
*Purpose: Recently, acute kidney injury is a important cause of chronic kidney injury, characterized by glomerular sclerosis and tubular fibrosis. Hypothermia attenuates the acute kidney…
2020 American Transplant Congress
Epithelial To Mesenchymal Transition Mediates Engraftment Of Endoderm And Hepatic Progenitor Cells In The Quiescent Liver
W. S. Fagg¹, N. Lui², L. Patrikeev³, O. Saldarriaga*⁴, H. Lerner-Stevenson⁵, V. Popov⁶, M. Motamade³, J. H. Fair¹
¹Surgery, University of Texas Medical Branch, Galveston, TX, ²Surgery, Naiyou Lui, Galveston, TX, ³Ophthalmology, University of Texas Medical Branch, Galveston, TX, ⁴Pathology, Omar Saldarriaga, Galveston, TX, ⁵pathology, University of Texas Medical Branch, Galveston, TX, ⁶Pathology, University of Texas Medical Branch, Galveston, TX
*Purpose: Stem cell transplantation to the liver is a promising therapeutic strategy for a variety of disorders. Hepatocyte transplantation has short term efficacy, but can…
2020 American Transplant Congress
Naïve B Cells Regulation by TLR-Breg Cells In Vitro
Q. Fu, K. Lee, G. Huai, K. Deng, N. J. Feeney, C. Leguern, S. Deng, J. F. Markmann
Center for Transplant Science, MGH, Boston, MA
*Purpose: Regulatory B cells (Bregs) have shown great potential in cell therapies for murine organ transplantation by inhibiting the proliferation of cytotoxic and helper T…
2020 American Transplant Congress
Analysis of the Mechanism of Liver-Resident NK Cells Activity via the Aryl Hydrocarbon Receptor
K. Sato, M. Ohira, Y. Imaoka, H. Ohdan
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
*Purpose: Tumor recurrence is the main limitation of liver transplantation (LT) in patients with hepatocellular carcinoma (HCC). We previously reported an adoptive immunotherapy approach that…
2020 American Transplant Congress
Targeting Th17: TIGIT as a Key Regulator of Tregs/Th17 Cells in Belatacept Resistant Rejection
C. R. Hartigan, M. Wagener, M. L. Ford
Emory University Transplant Center, Emory University, Atlanta, GA
*Purpose: Belatacept resistant-rejection (BRR) is a major barrier to the widespread adoption of immune checkpoint blockade therapeutics in transplantation. Our lab has shown that patients…
2020 American Transplant Congress
Tolerant Liver Transplant Patients Have Higher Level of Y RNA Fragments in the Circulation
C. Kuscu¹, A. Wolen¹, A. Bajwa¹, C. Kuscu¹, J. Eason², B. Ramaswami³, D. Maluf¹, G. Mazariegos³, G. Chalasani³, V. Mas¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ²James D. Eason Transplant Institute, Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ³Thomas E. Starzl Transplantation Institute, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Tolerance post transplantation continue to be the ultimate goal in transplantation. Circulating small RNAs are one of the best candidates for biomarker studies. To…
2020 American Transplant Congress
Diagnostic Method of Acute Kidney Rejection after Transplantation Using Metabolome Analysis via a Liquid Biopsy Approach
H. Iwamoto
Department of Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan
*Purpose: At present, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy…
2020 American Transplant Congress
Assessment of Deceased Donor Kidney and Liver Surgical Recovery Error Rates
R. D. Hasz, S. M. West, H. M. Nathan
Gift of Life Donor Program, Philadelphia, PA
*Purpose: There is no nationally available data related to the incidence of surgical errors in deceased donor organ recoveries or its impact on organ discard…