Am J Transplant, Volume 20, Suppl 3 Archives - Page 67 of 223 - ATC Abstracts

2020 American Transplant Congress
Dosing and Outcomes of Conversion to Extended-Release Tacrolimus in Heart and Lung Transplant Recipients
C. Doligalski¹, K. Walter¹, P. Chang², L. J. Lobo²
¹University of North Carolina Medical Center, Chapel Hill, NC, ²Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: Extended release tacrolimus (LCP-Tac) is a novel once daily formulation with improved pharmacokinetic parameters compared to immediate release tacrolimus (IR-Tac). LCP-Tac use in renal…
2020 American Transplant Congress
Heart Transplant Outcomes for Patients with Left Ventricular Assist Devices (LVAD) Before and after the 2018 Revision of the United Network for Organ Sharing (UNOS) Adult Heart Allocation System
J. Pizula¹, K. Yang¹, J. Li¹, S. Shah¹, G. Liu¹, A. Lee¹, P. Banankhah¹, J. Nattiv¹, D. Miklin¹, P. Genyk¹, P. Kingsford¹, K. Pandya¹, R. Joeseph¹, M. Fong¹, G. Luanda¹, A. Kiankhooy¹, S. Hashmi¹, S. Nuno¹, A. Wolfson², A. Salimbangon³, R. Chand⁴, D. Vucicevic⁵, L. Corey⁶, E. Depasquale¹, A. Vaidya¹
¹Cardiology, LAC-USC, Los Angeles, CA, ²University of Arizona Sarver Heart Center, Tuscon, AZ, ³UCLA Medical Center, Los Angeles, CA, ⁴Harbor-UCLA Medical Center, Los Angeles, CA, ⁵Newark Beth-Israel Medical Center, Newark, NJ, ⁶The Queen's Medical Center, Honolulu, HI
*Purpose: In October of 2018 UNOS chaged their adult heart allocation criteria to address disparity in waiting list survival. The implications of this policy change…
2020 American Transplant Congress
Characteristics and Outcomes of Patients with Cystic Fibrosis Receiving Lung Transplant with and without ECMO Bridge – A Single Center Experience
J. Loeb, S. Pirrotta, P. Chung, S. Ganesh
Pulmonary & Critical Care, USC, Los Angeles, CA
*Purpose: ECMO is a viable bridge to lung transplantation (LTx) for end-stage cystic fibrosis (CF) patients refractory to traditional medical support. We sought to identify…
2020 American Transplant Congress
Chronic Hyperammonemia an Important Cause of Morbidity in Isolated Intestine Transplant Patients with Venous Outflow to the Vena Cava
R. S. Mangus, C. A. Kubal, T. Burch, B. Ekser, P. Mihaylov, J. Fridell
Indiana University, Indianapolis, IN
*Purpose: There are limited options for superior mesenteric vein (SMV) outflow in isolated intestine transplant (ITx), the two most common being anastomosis to the recipient…
2020 American Transplant Congress
Total Pancreatectomy with Islet Autotransplantation in Diabetic and Prediabetic Patients with Intractable Chronic Pancreatitis
P. J. Bachul¹, D. J. Grybowski¹, R. Anteby², L. Basto¹, L. Perea¹, K. Golab¹, L. Wang¹, M. Tibudan¹, A. Perez-Gutierrez¹, M. Komorniczak³, S. Nagpal⁴, A. Lucander¹, P. Borek¹, M. Dimitrov¹, J. Fung¹, J. B. Matthews¹, P. Witkowski¹
¹Surgery, University of Chicago, Chicago, IL, ²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland, ⁴Medicine, University of Chicago, Chicago, IL
*Purpose: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment option for non-diabetic patients with intractable chronic pancreatitis. The outcome and potential benefits for…
2020 American Transplant Congress
Ex Vivo Isolated Human Vessel Perfusion System for the Design and Assessment of Nanomedicines Targeted to the Endothelium
L. G. Bracaglia¹, T. Lysyy², L. Qin², C. Albert¹, J. S. Pober², G. Tellides², W. M. Saltzman¹, G. T. Tietjen²
¹Yale University, New Haven, CT, ²Yale School of Medicine, New Haven, CT
*Purpose: In solid organ transplantation the host immune system acts to reject the graft. This process is facilitated at the endothelial surface, where inflamed donor…
2020 American Transplant Congress
A Recombinant, Fully Human ATG Polyclonal Antibody Drug Drives Immune Cell Depletion in a Model of Graft-versus-Host Disease
S. M. Keating, A. S. Adler, R. A. Mizrahi, J. Leong, M. A. Asensio, Y. W. Lim, A. R. Niedecken, Y. Chiang, R. Leong, D. S. Johnson
Immunology, GigaGen, South San Francisco, CA
*Purpose: Anti-thymocyte globulin (ATGs) are polyclonal antibody products that target and deplete T cells for immunosuppression in transplantation (prophylaxis of rejection). Since ATGs are derived…
2020 American Transplant Congress
Src Induces Endothelial-to-Mesenchymal Transition and Renal Allograft Fibrosis via Promoting WNT/β-catenin Pathway
W. Zijie, Z. Gui, M. Zheng, Z. Han, J. Tao, H. Chen, L. Sun, X. Ju, R. Tan, M. Gu
Jiangsu Province Hospital, Nanjing, China
*Purpose: Endothelial-to-mesenchymal(EndMT)is recognized as an important source of myofibroblasts contributing to the pathogenesis of allograft interstitial fibrosis in our previous studies. Increased proto-oncogene tyrosine-protein kinase…
2020 American Transplant Congress
Comparison of Anti-Thymocyte Globulin and Alemtuzumab as Induction Therapy in Older Kidney Transplant Recipients
M. Chaung, E. Hollinger, M. Brokhof, N. Alvey, L. Lineberger, N. Kenyon
Rush University Medical Center, Chicago, IL
*Purpose: The purpose of this study is to evaluate the safety and efficacy of induction with either anti-thymocyte globulin (ATG) (total dose 5 mg/kg) or…
2020 American Transplant Congress
The Application of Hypothermic Machine Perfusion in Kidney Transplantation from Delay Graft Function High Risk Donor
Y. Li, X. Hu, G. Chen, C. Ding, W. Xue
Kidney Transplantation Department, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
*Purpose: To investigate the clinical effect of the hypothermic machine perfusion (HMP) method on renal transplantation from high risk donation after citizen death (DCD) and…