Am J Transplant, Volume 20, Suppl 3 Archives - Page 6 of 223 - ATC Abstracts

2020 American Transplant Congress
Chronic Diarrhea in Renal Transplant Recipients: A Metagenomic Study of Gut Microbiota Composition and Functionality
J. C. Swarte¹, R. M. Douwes¹, S. Hu², R. Gacesa², H. J. Harmsen³, R. K. Weersma², S. J. Bakker¹
¹Internal Medicine - Nephrology, University Medical Centre Groningen, Groningen, Netherlands, ²Gastroenterology and Hepatology, University Medical Centre Groningen, Groningen, Netherlands, ³Medical Microbiology, University Medical Centre Groningen, Groningen, Netherlands
*Purpose: Chronic diarrhea is a common problem in renal transplant recipients (RTR) and can lead to a lower quality of life. However, in many patients…
2020 American Transplant Congress
Relapse-Prone Unresectable Hepatoblastoma (HB) Requiring Liver Transplantation (LT) Are Immunogenic and May Be Sensitive to Immune Checkpoint Inhibitors
M. Ningappa¹, C. Ashokkumar¹, J. Garifallou², M. Gonzalez², H. Hakonarson², S. Ranganathan¹, B. W. Higgs¹, R. Sindhi¹
¹Pediatric Transplant, Pittsburgh, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA
*Purpose: Unresectable HB accounts for 8% of all pediatric LT. Post-LT relapse rates approach 20% indicating a need for more effective neoadjuvant chemotherapy.*Methods: To discover…
2020 American Transplant Congress
Metformin Improves Biomarkers of Calcineurin Inhibitor Related Nephrotoxicity
M. R. Fernando, K. Taylor, S. Herath, A. Au, J. Erlich, Z. Endre
Department of Nephrology, Prince of Wales Hospital, Randwick, Australia
*Purpose: Calcineurin Inhibitors (CNIs) prevent transplant rejection but cause significant nephrotoxicity. Biomarkers of CNI nephrotoxicity could help drug dosing and improve long-term graft outcomes. As…
2020 American Transplant Congress
Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication During Cardiac Allograft Rejection in the Mouse Heart Transplantation
Y. Tang, X. Shi, X. He
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Allograft rejection is still the leading causes of the graft loss, especially long-term outcome. Single-cell genomics techniques are revolutionizing our ability to comprehensively characterize…
2020 American Transplant Congress
Changes in Gut Microbiota and Acute Rejection after Kidney Transplantation
H. Cho¹, J. Kim², H. Kim², J. Park³, M. Kwak⁴, B. Kim⁴, D. Kim², J. Lee⁵, B. Kim⁶, H. Lee²
¹Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea, Republic of, ²Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, ³Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea, Republic of, ⁴ChunLab Inc. Seoul National University, Seoul, Korea, Republic of, ⁵Department of Internal Medicine, Seoul National University Boramae Hospital, Seoul, Korea, Republic of, ⁶Department of Life Science, Multidisciplinary Genome Institute, Hallym University, Chuncheon, Korea, Republic of
*Purpose: Kidney transplantation (KT) is the best treatment for end-stage renal disease. Although rejection is a normal immune response of the body to a foreign…
2020 American Transplant Congress
Mitochondrial Metabolism is Enriched Following Normothermic Ex-Vivo Kidney Perfusion of Grafts Procured Following Cardiac Death
P. Urbanellis¹, C. McEvoy¹, L. Mazilescu¹, S. Ganesh¹, R. John¹, I. Mucsi¹, A. Ghanekar¹, D. Bagli², A. Konvalinka¹, L. Robinson², M. Selzner¹
¹University Health Network, Toronto, ON, Canada, ²The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Normothermic ex-vivo kidney perfusion (NEVKP) preservation has demonstrated superior graft outcomes for kidneys procured following donation-after-cardiac death (DCD) over static cold storage (SCS). To…
2020 American Transplant Congress
Outcomes of Kidney Donors with Impaired Fasting Glucose and Diabetes
S. Hebert, D. T. Nguyen, E. A. Graviss, H. E. Adrogue, A. Gaber, A. Matas, H. Ibrahim
Houston Methodist Hospital, Houston, TX
*Purpose: Many kidney donor candidates with impaired fasting glucose (IFG) and all candidates with diabetes (DM) are excluded from donation. The diagnostic thresholds for IFG…
2020 American Transplant Congress
Geographic Variation in Listing for Kidney Transplantation: A State-Level Assessment of Access among Patients with End-Stage Renal Disease in the United States
M. N. Mustian, H. Qu, D. Anderson, P. A. MacLennan, R. D. Reed, C. Kale, B. Orandi, B. A. Shelton, V. Kumar, M. Hanaway, J. E. Locke
University of Alabama at Birmingham, Birmingham, AL
*Purpose: Barriers to deceased donor kidney transplantation (DDKT) exist, including referral for transplant and waitlist addition, which may vary regionally. The objective of this study…
2020 American Transplant Congress
Higher Body Mass Index Before Living Kidney Donation Can Increase Wound Infection after Hand-Assisted Laparoscopic Living Donor Nephrectomies
X. Benavides, M. Merzkani, R. T. Rogers, E. K. Tan, S. Thirunavukkarasu, B. H. Smith, A. D. Rule, M. Prieto, J. K. Heimbach, T. Taner, G. K. Chow, P. G. Dean, M. D. Stegall
Kidney Transplant, Mayo Clinic, Rochester, MN
*Purpose: According to the CDC (2015-2016), 71.6% of the adult population in the United States has a BMI equal or higher than 25kg/m2, and the…
2020 American Transplant Congress
Calcium Level-Dependence of the Adverse Effect of Tertiary Hyperparathyroidism on Graft Survival in Renal Transplant Recipients
M. Okada, T. Tomosugi, T. Hiramitsu, K. Futamura, A. Kanda, N. Goto, S. Narumi, T. Ichimori, Y. Watarai
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan
*Purpose: Tertiary hyperparathyroidism (THPT) is a condition in which hyperparathyroidism persists after renal transplantation (RTx), and is a frequent complication. The aim of this retrospective…

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