Am J Transplant, Volume 20, Suppl 3 Archives - Page 55 of 223 - ATC Abstracts

2020 American Transplant Congress
Development of De Novo Antibody in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction
R. Hod Dvorai¹, R. Lee², P. Muluhngwi², M. Raijmakers³, A. Shetty², A. Tambur², M. Ison²
¹Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, ²Northwestern University, Chicago, IL, ³University of Santiago, Santiago, Chile
*Purpose: To evaluate development of de novo donor specific antibodies (dnDSA) in Renal Transplant Recipients (RTR) with immunosuppression (IS) modulation due to BK viremia (BKV)…
2020 American Transplant Congress
Racial Disparities in Long-Term Outcomes in Kidney Transplantation from Elderly Donors in United States
S. Shah, B. Abu Jawdeh, S. Bumb, T. Kaur, M. Anand, A. Govil, R. Jain
University of Cincinnati, Cincinnati, OH
*Purpose: Kidney transplantation offers survival benefit and improved quality of life in end-stage renal disease patients. Because the waiting list continues to grow, there has…
2020 American Transplant Congress
Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion
G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
2020 American Transplant Congress
In-Depth Assessment of Ischemia/Reperfusion Injury in a Murine Model of Hindlimb Transplantation
F. Messner¹, K. Kadono², Y. Guo¹, B. Oh¹, J. Kupiec-Weglinski², G. Brandacher¹
¹Department of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Surgery, Division of Liver and Pancreas Transplantation, University of California, Los Angeles, Los Angeles, CA
*Purpose: Static cold storage (SCS) still represents the gold standard for organ and tissue preservation in transplantation. Ischemia/reperfusion injury (IRI) that occurs due to the…
2020 American Transplant Congress
Utilization of High Terminal Creatinine Kidney Donors for Simultaneous Kidney and Pancreas Transplantation
A. Montal, J. Torabi, N. Muhdi, J. Melvin, Y. Miura, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, E. Akalin, S. Greenstein, J. P. Rocca, J. A. Graham
Montefiore Medical Center, Bronx, NY
*Purpose: The use of kidneys with high terminal creatinine has been demonstrated in renal transplantation with excellent outcomes. Here we explore the use of high…
2020 American Transplant Congress
Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy
Y. Caliskan¹, B. Dirim², E. Aksoy², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
2020 American Transplant Congress
Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model
S. Jain¹, R. Plenter², T. Nydam², A. Jani¹
¹Renal, University of Colorado, Aurora, CO, ²Transplant Microsurgery Program, University of Colorado, Aurora, CO
*Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…
2020 American Transplant Congress
Treg Stability Depends on Lymphotoxin Beta Receptor-Driven Migration
V. Saxena, W. Piao, L. Li, Y. Xiong, C. Palusckievicz, T. Simon, M. Shirkey, R. Abdi, J. S. Bromberg
University of Maryland, Baltimore, Baltimore, MD
*Purpose: Regulatory T cell (Treg) suppressor function for allograft survival requires maintenance of transcription factor Foxp3 and sequential migration from tissues to lymph nodes (LN).…
2020 American Transplant Congress
Improved Survival of Acute Liver Failure by “Off-the-Shelf” Bioartificial Liver Support System Using Immobilized Cryopreserved Hepatocyte Spheroids in Porcine Model
S. Lee¹, J. Lee², H. Park², Y. Kim², J. Noh³, J. Jung³, S. Lee³, H. Shin³, H. Yoon⁴, D. Lee³, S. Lee¹
¹Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of, ²Stem Cell and Regenerative Medicine Center, Research Institute for Future Medicine, Samsung Medical Center, Seoul, Korea, Republic of, ³Biomedical Research Center, Lifeliver, Co. Ltd., Yongin, Korea, Republic of, ⁴Biomedical Research Center, Lifeliver, Co. Ltd., Seoul, Korea, Republic of
*Purpose: Acute liver failure (ALF) has a rapid and unpredictable onset with high mortality. The only current treatment is to transplant a donor organ but…
2020 American Transplant Congress
Natural Antibodies and Left Ventricular Assist Device Complications
S. B. See¹, D. Onat², E. Hittesdorf³, F. McDougan⁴, M. Yuzefpolskaya², V. K. Topkara², Y. Naka⁵, H. Takayama⁵, K. Takeda⁵, G. Milligan⁶, D. Wencker⁶, S. Hall⁶, M. Askar⁶, P. Kimball⁴, G. Wagener³, P. C. Colombo², E. Zorn¹
¹Columbia Center for Translational Immunology, Columbia University Irving Medical Center, New York, NY, ²Department of Medicine, Columbia University Irving Medical Center, New York, NY, ³Department of Anesthesiology, Columbia University Irving Medical Center, New York, NY, ⁴Department of Transplant Surgery, Virginia Commonwealth University, Richmond, VA, ⁵Department of Surgery, Columbia University Irving Medical Center, New York, NY, ⁶Center for Advanced Heart and Lung Disease, Baylor University Medical Center, Dallas, TX
*Purpose: Left ventricular assist device (LVAD) implantation is followed by a sharp increase in serum levels of IgG natural antibodies (Nabs) recognizing oxidation-specific epitopes (OSE)…