ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Incidence of Cytomegalovirus and Role of Reduced Dose Valganciclovir in Kidney Transplant Recipients

    A. Szczepanik1, E. Metzker1, C. Burrelli1, K. Chavin2

    1Pharmacy, University Hospitals Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH

    *Purpose: Valganciclovir (VGC) is the optimal agent for preventing cytomegalovirus (CMV) but its use is limited by cost and leukopenia. Reduced dose VGC (rVGC) has…
  • 2020 American Transplant Congress

    Characteristics of Early BK Viremia after Renal Transplantation at an Urban Academic Medical Center

    K. Kurzweil, K. Lamartina, K. Svaflarska, D. Kutrzuba, N. Fayyaz, O. Piatek, P. West-Thielke, Z. Hajjiri, I. Tzvetanov, E. Benedetti, A. Lichvar

    University of Illinois at Chicago, Chicago, IL

    *Purpose: BK viremia (BKV) is a deleterious complication after renal transplantation that can compromise allograft function. Centers face the challenge of identifying at-risk patients and…
  • 2020 American Transplant Congress

    Inequitable Access to Living Donor Kidney Transplantation in Black and Asian Minority Ethnic Groups in the UK: A Single Centre Cross-Sectional Cohort Study

    A. Cronin, K. Sran, R. Gokmen, A. Copley, L. Silas, R. Zakri

    Guy's and St. Thomas' Hospital, London, United Kingdom

    *Purpose: Black, Asian and Minority Ethnic (BAME) communities constitute 11% of the UK population, yet represent 31% of the national kidney transplant waiting list. Moreover,…
  • 2020 American Transplant Congress

    Bridging the Gap: Normothermic Perfusion of Discarded Livers Significantly Alleviates the Donor Shortage

    S. Raigani, R. J. De Vries, C. Carroll, Y. Chen, D. C. Chang, K. Uygun, H. Yeh

    Transplant Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: European studies have shown that discarded liver grafts can be successfully transplanted if they meet viability criteria during normothermic machine perfusion (NMP). The potential…
  • 2020 American Transplant Congress

    Non-Invasive Near Infrared Fluorescence Based Monitoring of Macrophage Mediated Inflammation

    H. Karagoz1, N. Vettikattu1, F. Selek1, H. Kapucu1, E. Goktas1, L. Liu2, Y. Kulahci1, F. Zor1, J. M. Janjic2, V. S. Gorantla1

    1Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 2Department of Pharmaceuticals, Duquesne University, Pittsburgh, PA

    *Purpose: Clinical assessments for inflammation and acute rejection (AR) require regular, invasive biopsies followed by staining protocols that provide static images of tissue. Despite such…
  • 2020 American Transplant Congress

    TPIAT Outcomes in Diabetic and Non-Diabetic Patients with Chronic Pancreatitis

    M. A. Kanak, P. Saravanan, J. Kalivarathan, G. Hobbs, M. F. Levy

    Virginia Commonwealth University, Richmond, VA

    *Purpose: Total pancreatectomy with islet auto-transplantation (TPIAT) is becoming the standard of care for patients with severe chronic pancreatitis (CP). However, it is necessary to…
  • 2020 American Transplant Congress

    Urinary APOA4 as a Biomarker for Chronic Renal Allograft Injury and Rapid Renal Function Decline in Kidney Transplant Recipients

    H. Jeon1, D. Shin1, J. Oh1, J. Park2, K. Ko3, J. Kim3, S. Lee3

    1Department of Internal Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, 2Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of, 3Department of Surgery, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea, Republic of

    *Purpose: Chronic renal allograft injury (CRAI) remains a major cause of allograft loss in kidney transplant recipients (KTRs). The aim of this study was to…
  • 2020 American Transplant Congress

    Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside

    Y. Liu1, T. Lu2, C. Zhang1, Z. Xue1, R. Busuttil1, J. Kupiec-Weglinski1, H. Ji1

    1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Shanghai Jiaotong University, Shanghai, China

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…
  • 2020 American Transplant Congress

    Challenges in Manufacturing Clinically Competent Regulatory T Cells from Obese Renal Transplant Recipients

    F. Marti, A. Ruffing, E. Chacon, L. Turcios, D. Valvi, J. Gonzalez, R. Gedaly

    Surgery, University of Kentucky, Lexington, KY

    *Purpose: The obesity epidemic has expanded rapidly over the last decade. Our program is developing a novel clinical protocol using expanded autologous regulatory T cell…
  • 2020 American Transplant Congress

    Construction of Three-Dimensional Vascularized Functional Beta-Cells Tissues Using a Layer-by-Layer Cell Coating Technique

    S. Takaichi1, T. Akagi2, Y. Tomimaru1, S. Kobayashi1, Y. Iwagami1, H. Akita1, T. Noda1, K. Gotoh1, Y. Doki1, M. Akashi2, H. Eguchi1

    1Department of Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan, 2Building Block Science Joint Research Chair, Graduate School of Frontier Biosciences, Osaka University, Suita, Japan

    *Purpose: Regenerative therapy for type I Diabetes Mellitus has been expected to be a promising treatment. A subcutaneous site is an ideal candidate for stem…
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