ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Feasibility and Long Term Safety of T Regulatory Cell Therapy in Kidney Transplantation

    P. N. Harden1, D. Game2, J. Van der Net1, F. Issa3, W. Petchey1, M. Brook1, P. Friend1, R. Hilton4, G. Lombardi5, K. Wood3

    1Kidney Transplantation, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, 2Kidney Transplantation, Guys and St Thomas's Hospital, London, United Kingdom, 3Transplant Immunology Research Group, Oxford University, Oxford, United Kingdom, 4Kidney Transplantation, Guys and St Thomas's Hospital, Oxford, United Kingdom, 5Transplant Immunology Group, Kings Healthcare Partners, London, United Kingdom

    *Purpose: A sequential clinical trial of autologous polyclonal T regulatory cellular therapy compared with a standardised reference cohort of live donor kidney transplant recipients. The…
  • 2020 American Transplant Congress

    Protocolized Exercise Improves Frailty Parameters and Lower Extremity Impairment: A Promising Prehabilitation Strategy for Kidney Transplant Candidates

    E. C. Lorenz, L. J. Hickson, R. Weatherly, K. Thompson, H. Walker, J. Rasmussen, T. Stewart, J. Garrett, C. C. Kennedy

    Mayo Clinic, Rochester, MN

    *Purpose: Frailty and lower extremity (LE) impairment are risk factors for numerous adverse outcomes in kidney transplant (KT) candidates, including decreased rates of transplantation, increased…
  • 2020 American Transplant Congress

    Living Kidney Donation is Associated with Accelerated Podocyte Loss Early after Donation

    A. S. Naik, D. Le, S. Wang, M. Chowdhury, M. D. Doshi, R. Wiggins

    University of Michigan, Ann Arbor, MI

    *Purpose: Living kidney donation (LKD) is associated with increased long-term risk of CKD/ESRD. Post donation DM/HTN are associated with this increased risk. However, the remaining…
  • 2020 American Transplant Congress

    Liver Retransplantation (reLT) in the Modern Post-MELD, Post-DAA Era

    B. Shi, C. Freise, D. Brandman

    School of Medicine, UCSF, San Francisco, CA

    *Purpose: Liver retransplantation (reLT) is responsible for a small proportion of all liver transplants (LT), but outcomes are much worse than primary LT. Hepatitis C…
  • 2020 American Transplant Congress

    A Survey of Lung Transplant Recipient Attitudes and Beliefs on Accepting an Organ That Was Positive for Hepatitis C Virus

    S. S. Humar1, N. Pinzon1, M. Cypel1, S. Abbey2

    1University Health Network, Transplant Center, Toronto, ON, Canada, 2University Health Network, Center for Mental Health, Toronto, ON, Canada

    *Purpose: Recent data show that organs from donors who are HCV positive (+ve) can be safely transplanted into HCV negative recipients. We conducted a survey…
  • 2020 American Transplant Congress

    Roles of Calpastatin in Ischemia/Reperfusion Injury in Aged Livers

    J. Kim, C. Lee, W. Chapman

    Surgery, Washington University St. Louis, St. Louis, MO

    *Purpose: Aged livers are far more susceptible to ischemia/reperfusion (I/R) injury than young livers. No therapeutic strategies are available to reduce I/R injury in elderly…
  • 2020 American Transplant Congress

    Role of Innate Allorecognition Pathways in Mouse Kidney and Heart Allograft Rejection

    D. Zhao1, H. Dai1, K. Abou-Daya1, R. Tieu1, A. Williams1, M. Oberbarnscheidt1, X. Li2, F. Lakkis1

    1Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 2Houston Methodist Hospital Immunobiology & Transplant Science Center, Houston, TX

    *Purpose: Paired immunoglobulin-like receptors (PIR) and CD47 are molecules expressed on host myeloid cells. They recognize donor polymorphic MHC and signal regulatory protein alpha (SIRPα),…
  • 2020 American Transplant Congress

    An Evaluation of Deceased Donor Eligibility and US Organ Donation Rates

    L. DeRoos1, Y. Zhou2, W. Marrero1, M. Lavieri1, D. Hutton3, N. Parikh4

    1Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI, 2Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, 3School of Public Health, University of Michigan, Ann Arbor, MI, 4Internal Medicine, University of Michigan, Ann Arbor, MI

    *Purpose: Organ Procurement Organization (OPO) performance assessment is essential for identifying best practices and improvement opportunities. We aimed to evaluate OPO performance using the following…
  • 2020 American Transplant Congress

    The Urine Qisant Score: Non-Invasive, Accurate, Diagnosis and Prediction of Kidney Transplant Rejection

    J. Y. Yang1, R. Sarwal1, T. Sigdel1, I. Damm1, B. Rosenbaum1, J. Liberto1, C. Chan-On1, J. Alberu2, F. Vincenti1, M. M. Sarwal1

    1University of California San Francisco, San Francisco, CA, 2University of Mexico, Instituto Nacional De Ciencias Medicas y Nutricion, San Francisco, CA

    *Purpose: Accurate and non-invasive monitoring of renal allografts post-transplant is essential for early detection of acute rejection (AR) and to directly impact the long-term survival…
  • 2020 American Transplant Congress

    Factors Predicting Outcome after Living Donor Liver Transplantation in the Era of Intra-Operative Flow Measurements and Inflow Modulation

    D. Sonbare, D. Jorgensen, A. Humar

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: To identify pre/intra-operative factors which predict adverse outcome after living donor liver transplantation (LDLT).*Methods: All patients who underwent first LDLT at UPMC, Pittsburgh from…
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