ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
  • 2020 American Transplant Congress

    A Stroke Volume-Based Fluid Resuscitation Protocol Decreases Vasopressor Support and Increases Organ Yield in Brain-Dead Donors

    G. F. Marklin

    Mid-America Transplant, St Louis, MO

    *Purpose: Brain-dead donors are frequently hypovolemic and hypotensive requiring vasopressor support. The goal of fluid resuscitation is to increase perfusion and oxygen delivery and avoid…
  • 2020 American Transplant Congress

    Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant

    T. Egan1, S. Arunachalam2, C. Chang2, P. Strassle1

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Institute of the Environment, UNC at Chapel Hill, Chapel Hill, NC

    *Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…
  • 2020 American Transplant Congress

    T and B Lymphocyte Dynamics after Genetically-Modified Pig-To-Baboon Kidney Xenotransplantation with an Anti-CD40mAb-Based Immunosuppressive Regimen

    A. Jagdale1, H. Iwase1, H. Nguyen1, T. Yamamoto1, D. Ayares2, D. Anderson1, D. Eckhoff1, D. Cooper1, H. Hara1

    1Surgery, University of Alabama at birmingham, Birmingham, AL, 2Revivicor, Blacksburg, VA, VA

    *Purpose: We have evaluated recovery of T and B lymphocytes and their subsets after depletion by anti-thymocyte globulin (ATG) and an anti-CD20mAb (Rituximab), followed by…
  • 2020 American Transplant Congress

    One Year of COIIN Outcomes: Did Cohorts A and B Maintain Graft Survival?

    J. Foutz, R. J. Carrico, K. Sisaithong, H. Tosoc-Haskell, D. Klassen

    United Network for Organ Sharing, Richmond, VA

    *Purpose: The Collaborative Innovation and Improvement Network (COIIN) was a 3-year OPTN project aimed at increasing the utilization of kidneys with a kidney donor profile…
  • 2020 American Transplant Congress

    Empowering Recipients Through a Champion Program: A Life Saving Initiative

    C. L. Rochon, D. Woch, K. Rancourt, O. K. Serrano, A. K. Asamoah

    Transplantation, Hartford Hospital, Hartford, CT

    *Purpose: Our purpose was to increase access to living donor kidney transplantation for patients referred at our center. With our interventions, our patients and their…
  • 2020 American Transplant Congress

    Living Donor Liver Transplantation for Unresectable Liver Confined Colorectal Liver Metastases: A North American Experience

    L. I. Ruffolo, K. Dokus, M. Larye, J. Errigo, J. Bhoely, R. Dunne, M. Levstik, B. Al-Jadaibi, K. Tomiyama, R. Hernandez-Alejandro

    Surgery, University of Rochester Medical Center, Rochester, NY

    *Purpose: Colorectal cancer is the third leading cause of cancer related death, and 50% of patients will either present with synchronous or develop colorectal liver…
  • 2020 American Transplant Congress

    Donor Derived Transmissions 2018: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)

    M. Michaels1, B. Plucinski2, E. Ward2, L. Strasfeld1, M. Malinis1, C. Ho1, L. Danziger-Isakov1, J. Bucio1, G. Berry1, M. Rana1, C. Marboe1, S. Aslam1, R. Razonable1, S. Pouch1, G. F. Marklin1, J. Levitsky1, D. Levine1, A. Agarwal1, R. LaHoz1

    1OPTN DTAC, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: The OPTN DTAC, a multidisciplinary group, evaluates potential donor derived transmission events (PDDTE), mostly infections (I) & malignancies (M), to assess the likelihood of…
  • 2020 American Transplant Congress

    Three-Year Post-Transplant Outcome of Desensitized Mechanical Circulatory Support Patients Awaiting Heart Transplantation

    J. Youn1, R. Cole2, D. Ramzy2, E. Kim1, J. Kobashigawa2, J. Moriguchi2

    1Seoul St. Mary's Hospital, Seoul, Korea, Republic of, 2Cedars-Sinai Heart Institute, Los Angeles, CA

    *Purpose: Up to 30% of durable mechanical circulatory support (MCS) patients (pts) develop panel reactive antibody (PRA) screen >= 10%. In our program, desensitization (DS)…
  • 2020 American Transplant Congress

    Proteomics and Metabolomics Technologies Reveal the Effect of Oxygen in Hypothermic Machine Perfusion to Alleviate Donation after Circulatory Death Liver Injury

    X. Zeng1, X. Fan2, Y. Wang2, Q. Xia1, J. Liu1, H. Li1, Q. Ye2, Z. Wang1

    1Department of Urology, Union Hospital, Affiliated TongJi Medical College, Huazhong University of Science & Technology, Wuhan, China, 2Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Wuhan, China

    *Purpose: To compare the effects of oxygenated and nitrogenated hypothermic machine perfusion on the preservation of donation after circulatory death (DCD) livers, and to explore…
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