Am J Transplant, Volume 20, Suppl 3 Archives - Page 223 of 223 - ATC Abstracts

2020 American Transplant Congress
Activated CD27⁺CD21^– Subset Dominate the Memory B Cell Response During Antibody-Mediated Rejection of Kidney Allografts
K. Louis¹, E. Bailly¹, C. Macedo¹, M. Marrari¹, M. Yamada¹, P. Randhawa¹, A. Zeevi¹, C. Lefaucheur², D. Metes¹
¹Surgery, University of Pittsburgh, Pittsburgh, PA, ²Inserm UMR 976, Paris, France
*Purpose: The role of alloreactive memory B (mB) cells in the pathogenesis of antibody-mediated rejection (ABMR) is increasingly recognized. Yet, a comprehensive characterization of mB…
2020 American Transplant Congress
Characterizing the Waitlist Candidate Who Was Bypassed by the Successfully Transplanted Candidate with Alcoholic Hepatitis
J. Ge¹, C. L. Berg², F. Y. Yao¹, J. P. Roberts³, J. C. Lai¹
¹Medicine - Gastroenterology, University of California, San Francisco, San Francisco, CA, ²Duke University, Durham, NC, ³Surgery, University of California, San Francisco, San Francisco, CA
*Purpose: Early liver transplantation (LT) for acute alcoholic hepatitis (AH) has increased dramatically in the US since 2016. Due to high MELD-Na scores, AH candidates…
2020 American Transplant Congress
Living Donor Liver Transplantation Should Be Considered Cautiously in Recurrent Hepatocellular Carcinoma within the Milan Criteria after Curative Liver Resection
J. Kim¹, N. Yi², G. Choi¹, C. D. Kwon³, K. Lee², K. Suh², J. Joh¹
¹Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, ²Division of HBP Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, ³Department of Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH
*Purpose: Insufficient data are available about patient survival following different treatments for recurrent hepatocellular carcinoma (HCC) after primary hepatectomy. We retrospectively evaluated the effects of…
2020 American Transplant Congress
Less is More: A Single Brain Death Exam Improves Organ Donation Outcomes
A. J. Matar¹, H. Wichmann², L. Kenney², A. Subramanian³, J. Ratcliff⁴, V. Patel⁴, B. M. Tracy², R. B. Gelbard²
¹Surgery and Transplantation, Emory University, Atlanta, GA, ²Surgery, Emory University, Atlanta, GA, ³Surgery, Lawnwood Regional Medical Center, Fort Pierce, FL, ⁴Neurosurgery, Emory University, Atlanta, GA
*Purpose: The diagnosis of brain death in adults has historically required two brain death examinations (TBD) before considering organ donation. Despite American Academy of Neurology…
2020 American Transplant Congress
An Optimized Integrative Model Using Urinary Chemokines for Noninvasive Diagnosis of Acute Allograft Rejection
C. Tinel¹, A. Devresse¹, A. Vermorel¹, D. Marx², S. Caillard², C. Legendre¹, M. Rabant³, D. Anglicheau¹
¹Nephrology and Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Nephrology and Kidney Transplantation, Strasbourg University Hospital, Strasbourg, France, ³Pathology, Necker Hospital, Paris, France
*Purpose: The aim of this study was to optimize the performance of urinary chemokines C-X-C motif ligand (CXCL) 9 and CXCL10 as noninvasive diagnostic markers…
2020 American Transplant Congress
Low HLA Class I Epitope Mismatch Associated with Improved Pancreas Graft Survival in Simultaneous Pancreas-Kidney Transplantation
J. M. Ladowski, M. Romine, D. Kloda, C. Young, J. Locke, V. Hauptfeld-Dolejsek, J. Houp
University of Alabama-Birmingham, Birmingham, AL
*Purpose: Antibody-mediated rejection remains the principal cause of allotransplant graft failure. Human leukocyte antigen (HLA) matching between donor and recipients significantly reduces the risk of…
2020 American Transplant Congress
Getting to Yes Faster: Multifactorial Filters to Reduce Unwanted Offers
A. Toll, H. McGehee, J. Rosendale, D. Stewart, R. McTier
United Network for Organ Sharing, Richmond, VA
*Purpose: Evaluate if multifactorial filters can reduce unwanted kidney offers to centers, thereby reducing administrative burden and getting to the accepting candidate quicker.*Methods: Using recursive…
2020 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies are Associated with Younger Age and Renal Dysfunction in Pediatric Kidney Transplantation
M. Pearl¹, E. T. Chambers², A. Kirk², R. Garro³, B. L. Warshaw³, P. Grimm⁴, R. Ettenger¹, E. Reed¹
¹UCLA, Los Angeles, CA, ²Duke, Durham, NC, ³Emory, Atlanta, GA, ⁴Stanford, Stanford, CA
*Purpose: The significance of non-HLA antibodies in renal transplantation remains unclear. In small single center retrospective studies, angiotensin II type 1 receptor antibody (AT1R-Ab) has…