2020 American Transplant Congress
Hypernatremia Predicts Waitlist Death and Deterioration, but Not Post-Transplant Outcomes in Pediatric Liver Transplant Candidates
*Purpose: Pre-transplant hypernatremia has been shown to predict post-transplant mortality in adult liver transplant (LT) recipients. The effects of hypernatremia in children, however, remain unexplored.…2020 American Transplant Congress
Rates of Urinary Tract Infections in Kidney Transplant Patients Using Trimethoprim/Sulfamethoxazole versus Alternative Agents for Pneumocystis Jiroveci Prophylaxis
Hennepin Healthcare, Minneapolis, MN
*Purpose: Trimethoprim/sulfamethoxazole (TMP/SMX) is used in kidney transplant patients for prophylaxis against Pneumocystis jiroveci pneumonia (PJP) and has demonstrated a decrease in the incidence of…2020 American Transplant Congress
Development of De Novo Antibody in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction
*Purpose: To evaluate development of de novo donor specific antibodies (dnDSA) in Renal Transplant Recipients (RTR) with immunosuppression (IS) modulation due to BK viremia (BKV)…2020 American Transplant Congress
Racial Disparities in Long-Term Outcomes in Kidney Transplantation from Elderly Donors in United States
University of Cincinnati, Cincinnati, OH
*Purpose: Kidney transplantation offers survival benefit and improved quality of life in end-stage renal disease patients. Because the waiting list continues to grow, there has…2020 American Transplant Congress
Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion
*Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…2020 American Transplant Congress
In-Depth Assessment of Ischemia/Reperfusion Injury in a Murine Model of Hindlimb Transplantation
*Purpose: Static cold storage (SCS) still represents the gold standard for organ and tissue preservation in transplantation. Ischemia/reperfusion injury (IRI) that occurs due to the…2020 American Transplant Congress
Utilization of High Terminal Creatinine Kidney Donors for Simultaneous Kidney and Pancreas Transplantation
Montefiore Medical Center, Bronx, NY
*Purpose: The use of kidneys with high terminal creatinine has been demonstrated in renal transplantation with excellent outcomes. Here we explore the use of high…2020 American Transplant Congress
Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy
*Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…2020 American Transplant Congress
Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model
*Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…2020 American Transplant Congress
Treg Stability Depends on Lymphotoxin Beta Receptor-Driven Migration
University of Maryland, Baltimore, Baltimore, MD
*Purpose: Regulatory T cell (Treg) suppressor function for allograft survival requires maintenance of transcription factor Foxp3 and sequential migration from tissues to lymph nodes (LN).…