ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Hypernatremia Predicts Waitlist Death and Deterioration, but Not Post-Transplant Outcomes in Pediatric Liver Transplant Candidates

    L. Thalji1, N. Thalji2, S. Ibrahim3, J. Heimbach2, P. Kamath4, D. Haile1, D. Kor1

    1Anesthesiology, Mayo Clinic, Rochester, MN, 2Surgery, Mayo Clinic, Rochester, MN, 3Pediatric Gastroenterology, Mayo Clinic, Rochester, MN, 4Gastroenterology, Mayo Clinic, Rochester, MN

    *Purpose: Pre-transplant hypernatremia has been shown to predict post-transplant mortality in adult liver transplant (LT) recipients. The effects of hypernatremia in children, however, remain unexplored.…
  • 2020 American Transplant Congress

    Rates of Urinary Tract Infections in Kidney Transplant Patients Using Trimethoprim/Sulfamethoxazole versus Alternative Agents for Pneumocystis Jiroveci Prophylaxis

    L. C. Laird, R. M. Nygaard, T. L. Anderson-Haag, A. M. Spenningsby, P. A. Stahler

    Hennepin Healthcare, Minneapolis, MN

    *Purpose: Trimethoprim/sulfamethoxazole (TMP/SMX) is used in kidney transplant patients for prophylaxis against Pneumocystis jiroveci pneumonia (PJP) and has demonstrated a decrease in the incidence of…
  • 2020 American Transplant Congress

    Development of De Novo Antibody in Renal Transplant Recipients with BK Viremia Managed with Immunosuppression Reduction

    R. Hod Dvorai1, R. Lee2, P. Muluhngwi2, M. Raijmakers3, A. Shetty2, A. Tambur2, M. Ison2

    1Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, 2Northwestern University, Chicago, IL, 3University of Santiago, Santiago, Chile

    *Purpose: To evaluate development of de novo donor specific antibodies (dnDSA) in Renal Transplant Recipients (RTR) with immunosuppression (IS) modulation due to BK viremia (BKV)…
  • 2020 American Transplant Congress

    Racial Disparities in Long-Term Outcomes in Kidney Transplantation from Elderly Donors in United States

    S. Shah, B. Abu Jawdeh, S. Bumb, T. Kaur, M. Anand, A. Govil, R. Jain

    University of Cincinnati, Cincinnati, OH

    *Purpose: Kidney transplantation offers survival benefit and improved quality of life in end-stage renal disease patients. Because the waiting list continues to grow, there has…
  • 2020 American Transplant Congress

    Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion

    G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

    *Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
  • 2020 American Transplant Congress

    In-Depth Assessment of Ischemia/Reperfusion Injury in a Murine Model of Hindlimb Transplantation

    F. Messner1, K. Kadono2, Y. Guo1, B. Oh1, J. Kupiec-Weglinski2, G. Brandacher1

    1Department of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Surgery, Division of Liver and Pancreas Transplantation, University of California, Los Angeles, Los Angeles, CA

    *Purpose: Static cold storage (SCS) still represents the gold standard for organ and tissue preservation in transplantation. Ischemia/reperfusion injury (IRI) that occurs due to the…
  • 2020 American Transplant Congress

    Utilization of High Terminal Creatinine Kidney Donors for Simultaneous Kidney and Pancreas Transplantation

    A. Montal, J. Torabi, N. Muhdi, J. Melvin, Y. Miura, M. Ajaimy, L. Lirano, Y. Azzi, C. Pynadath, E. Akalin, S. Greenstein, J. P. Rocca, J. A. Graham

    Montefiore Medical Center, Bronx, NY

    *Purpose: The use of kidneys with high terminal creatinine has been demonstrated in renal transplantation with excellent outcomes. Here we explore the use of high…
  • 2020 American Transplant Congress

    Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy

    Y. Caliskan1, B. Dirim2, E. Aksoy2, R. Ouseph1, Y. Ozluk3, H. Randall4, F. Savran Oguz5, A. Turkmen2, M. S. Sever2, K. Lentine1

    1Division of Nephrology, Saint Louis University, Saint Louis, MO, 2Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, 3Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, 4Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, 5Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey

    *Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
  • 2020 American Transplant Congress

    Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model

    S. Jain1, R. Plenter2, T. Nydam2, A. Jani1

    1Renal, University of Colorado, Aurora, CO, 2Transplant Microsurgery Program, University of Colorado, Aurora, CO

    *Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…
  • 2020 American Transplant Congress

    Treg Stability Depends on Lymphotoxin Beta Receptor-Driven Migration

    V. Saxena, W. Piao, L. Li, Y. Xiong, C. Palusckievicz, T. Simon, M. Shirkey, R. Abdi, J. S. Bromberg

    University of Maryland, Baltimore, Baltimore, MD

    *Purpose: Regulatory T cell (Treg) suppressor function for allograft survival requires maintenance of transcription factor Foxp3 and sequential migration from tissues to lymph nodes (LN).…
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