ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Autophagy Attenuates Renal Allograft Interstitial Fibrosis by Regulating the EndMT Induced by TNF-α

    Z. Gui, C. Suo, Z. Wang, S. Fei, Z. Han, J. Tao, H. Chen, L. Sun, X. Ju, R. Tan, M. Gu

    Jiangsu Province Hospital, Nanjing, China

    *Purpose: Kidney interstitial fibrosis is a significant cause of allograft failure in kidney transplantation. Autophagy is a self-digestive process that eliminates impaired or aged proteins…
  • 2020 American Transplant Congress

    Effect of Rituximab Dose as Induction Therapy in ABO Incompatible Living Kidney Transplantation A Systemic Review and Network Meta Analysis

    S. Hwang1, W. Park2, K. Kim1, S. Lee1, J. Song1

    1Inha University, Incheon, Korea, Republic of, 2Keimyung University, Daegu, Korea, Republic of

    *Purpose: ABO-incompatible living kidney transplantation (ABOILKT) has steadily become more widespread. However, the optimal immunosuppressive regimen for ABOILKT remains uncertain. We aimed to determine the…
  • 2020 American Transplant Congress

    Effects of Kidney Transplantation on Cystogenesis in Kidneys Procured from a Deceased Donor with Autosomal Dominant Polycystic Kidney Disease

    M. C. Chumley1, H. Kim2, D. M. Williams3, V. Kumar3, M. Mrug3

    1University of Alabama at Birmingham, Birmingham, AL, 2Radiology, University of Alabama at Birmingham, Birmingham, AL, 3Nephrology, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Autosomal Dominant Polycystic Kidney Disease (ADPKD) patients are not routinely considered as kidney donors for renal transplantation. This is partially due to a concern…
  • 2020 American Transplant Congress

    The Role of mTOR Inhibitors on Cardiovascular Aging in Renal Transplanted Patients with Chronic Graft Dysfunction

    G. Castellano1, B. Infante1, P. Pontrelli1, R. Franzin1, F. Rascio1, C. Prisciandaro2, L. Gesualdo1, N. Coviello3, G. Grandaliano3, G. Stallone3

    1Emergency and Organ Transplantation, University of Bari, Bari, Italy, 2University of Foggia, Foggia, Italy, 3Emergency and Organ Transplantation, University of Foggia, Foggia, Italy

    *Purpose: Chronic Kidney Disease (CKD) is strongly associated with increased circulatory complications that can lead to accelerated cardiovascular aging. During CKD, persistent oxidative stress triggered…
  • 2020 American Transplant Congress

    A Mouse Model of Non-MHC Mismatches Recapitulates Chronic Allograft Dysfunction and I-IFTA

    V. Pavlov1, F. Garzon1, R. Haroon Al Rasheed2, K. Banu1, F. ElSalem1, L. Li1, E. Cody1, M. Planoutene1, N. Chun1, Z. Zhang1, J. Leventhal1, B. Murphy1, P. Heeger1, M. C. Menon1

    1Medicine, Mount Sinai School of Medicine, New York, NY, 2Pathology, Mount Sinai School of Medicine, New York, NY

    *Purpose: Fibrotic and atrophic changes or IF/TA is an important cause of graft loss. We reported that genome-wide donor-recipient non-HLA mismatches independently correlate with Banff…
  • 2020 American Transplant Congress

    Patient Attitudes Regarding Contraception and Pregnancy after Transplantation

    P. Puerzer1, T. McIntosh2, C. Sammons3, N. Casciello3, T. Fallah3, M. Norris3, M. Sumit4, J. DuBois5, A. Iltis6, D. Sawinski1

    1Univ of Pennsylvania, Philadelphia, PA, 2Washington Univ in St Louis, St Louis, MO, 3Pharmacy, Hospital of the Univ of Pennsylvania, Philadelphia, PA, 4Columbia Univ, New York, NY, 5Washington Univ in St Louis, St. Louis, MO, 6Wake Forest Univ, Winston-Salem, NC

    *Purpose: Professional society recommendations regarding contraception and pregnancy after transplantation exist but little is known about patient attitudes.*Methods: We conducted a survey of female transplant…
  • 2020 American Transplant Congress

    Early Graft Function and Intrarenal Resistant Index after Kidney Transplantation Using New Preservation Fluid (Biolasol)

    A. Kolonko1, R. Król2, J. Chudek3, L. Cierpka2, A. Więcek1

    1Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland, 2General, Vascular and Transplant Surgery, Medical University of Silesia, Katowice, Poland, 3Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, Katowice, Poland

    *Purpose: Biolasol is a newly developed preserving solution for cold organ storage prior to transplantation. The aim of this study was to compare in the…
  • 2020 American Transplant Congress

    Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression During the First Year Post-Transplant (<1yr Tx) Increases Risk for CMV Infection Through Inhibition of Anti-CMV Humoral Immunity

    B. Shin, N. Ammerman, S. Sethi, A. Vo, S. C. Jordan, M. Toyoda

    Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: We have shown a higer CMV infection rate in kidney Tx patients (KTx Pts) who were converted to BLT 1yr post-Tx. Viral infections are…
  • 2020 American Transplant Congress

    Lowering Meld, Diminishing Length of Stay, and Increasing Liver Transplant Numbers Comes Through the Generosity of Others: Declined HCV-NAT Offers Subsequently Transplanted Have Excellent Outcomes

    R. Gilroy, S. Sell, J. Krong, A. Gagnon, I. Zendejas, S. Fujita, M. Rodriguez, D. Alonso

    Transplant Services, Intermountain Healthcare, Murray, UT

    *Purpose: There is variability between programs in the acceptance of organ offers. This paper examines offer, acceptance and program performance with HCV NAT positive donor…
  • 2020 American Transplant Congress

    Transplant Outcomes, Risk Factors, and Regional Variation in Selection of Morbidly Obese Liver Transplant Candidates in the US

    T. Lian1, N. Kaur2, J. Emamaullee2, M. Lo3, P. Ender4, J. Kahn5, L. Sher2

    1Keck School of Medicine at USC, Los Angeles, CA, 2Department of Surgery, Keck School of Medicine at USC, Los Angeles, CA, 3Department of Preventative Medicine, Keck School of Medicine at USC, Los Angeles, CA, 4Statistical Consulting Group, University of California Los Angeles, Los Angeles, CA, 5Department of Medicine, Keck School of Medicine at USC, Los Angeles, CA

    *Purpose: Body Mass Index (BMI) limits for liver transplant (LT) candidacy are controversial. We evaluated waitlist and post-LT outcomes, prognostic factors, and regional patterns of…
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