ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Successful Liver-Kidney Transplantation in a Highly Sensitized Pediatric Patient

    M. Bock, M. Chandran, J. Goebel, E. Blanchette, M. Wachs, M. Adams, S. Sundaram

    Children's Hospital Colorado, Denver, CO

    *Purpose: While immunologically challenging and controversial, we report a successful case of same donor staged simultaneous liver-kidney transplant (SLK) in a highly sensitized child against…
  • 2020 American Transplant Congress

    High Estimated Glomerular Filtration Rate at the First Year after Kidney Transplantation is Associated with Worse Long-Term Graft Survival in Kidney Recipient

    H. Choi1, K. Huh2, M. Kim2, S. Kim2, Y. Kim2, B. Kim1

    1Internal Medicine, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Department of Transplantation Surgery, Yonsei University College of Medicine, Seoul, Korea, Republic of

    *Purpose: High estimated glomerular filtration rate (eGFR) as well as low eGFR is associated with cardiovascular morbidity and mortality. The transplanted kidney in the recipient…
  • 2020 American Transplant Congress

    Change in Hypertension (HTN) Guidelines in Living Kidney Donors (LKDs) and Long-Term Renal Outcomes

    M. Merzkani1, A. Denic1, M. D'Costa1, L. Ricaurte1, R. Narasimhan1, X. Benavides1, A. Mullan1, J. Larson1, W. Kremer1, W. Park1, M. P. Alexander1, H. Chakkera2, S. Textor1, S. Taler1, M. Stegall1, N. Issa1, A. Rule1

    1Mayo Clinic Rochester, Rochester, MN, 2Mayo Clinic Rochester, Scottsdale, AZ

    *Purpose: There is limited knowledge regarding the long-term renal outcomes in hypertensive LKDs. We performed a multicenter study assessing long-term outcomes with or without HTN…
  • 2020 American Transplant Congress

    Clinical Outcomes in Kidney Transplant Recipients Following Implementation of a Strategic Maintenance Reduction Protocol

    H. Perkins, K. Foster, N. Patel, H. Meadows, F. Bartlett, C. Perez, J. McGillicuddy, N. Pilch, M. Casey, M. A. Posadas-Salas, D. Taber

    Pharmacy, Medical University of South Carolina, Charleston, SC

    *Purpose: Post-transplant complications are commonly due to over-immunosuppression, particularly as it relates to infections. The purpose of this study was to assess clinical outcomes in…
  • 2020 American Transplant Congress

    Simultaneous Liver and Kidney Transplantation—The Lack of Influence of Pre-Formed DSA

    A. Bhansali, F. Mahir, M. Facciuto, R. Shapiro, J. Crismale, T. Schiano, G. De Boccardo

    Recanati-Miller Transplantation Institute, Mount Sinai Hospital, New York, New York, NY

    *Purpose: It is known that renal transplant recipients with preformed donor specific antibodies (DSA) have poorer outcomes associated with episodes of acute rejection (AR) and…
  • 2020 American Transplant Congress

    Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors

    A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

    Johns Hopkins Hospital, Baltimore, MD

    *Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of…
  • 2020 American Transplant Congress

    Acute Liver Failure Etiology is an Independent Predictor of Waitlist Outcome Accounting for Severity of Illness in a National Cohort

    N. Z. Wong, K. R. Reddy, T. Bittermann

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Severity of illness and liver transplant (LT) waitlist outcome can differ according to acute liver failure (ALF) etiology. However, it is unknown whether ALF…
  • 2020 American Transplant Congress

    Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment

    I. H. Song1, K. Ilic2, J. Wu3

    1Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, 2Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, 3Biostat, Shire, a Takeda Company, Lexington, MA

    *Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
  • 2020 American Transplant Congress

    Impact and Outcomes of Primary Cytomegalovirus Infection in Seronegative Abdominal Solid Organ Transplant Recipients of Cytomegalovirus Unexposed Donors (D-/R-)

    M. Jorgenson1, M. Hillis1, N. Friedlander1, A. Gracon2, D. Yang2, G. Leverson2, J. Smith2, R. Redfield2

    1UWHC, Madison, WI, 2UWMF, Madison, WI

    *Purpose: Primary cytomegalovirus infection (CMV) in high risk (D+/R-) abdominal solid organ transplant recipients (aSOTRs) is well described, however there is a paucity of literature…
  • 2020 American Transplant Congress

    Long-Term Safety in Epstein-Barr Virus (EBV)-Seropositive Kidney-Only Transplant Recipients Treated with Belatacept (BELA) in Clinical Practice: Final Study Results from the ENLiST Registry

    C. Larsen1, F. Vincenti2, T. Kou3, C. Shadur4, B. Bresnahan5, S. Jordan6, E. S. Woodle7, N. Goes8, J. Vella9, D. Wojciechowski10, M. Polinsky3, A. Gomez-Caminero3

    1Emory University Transplant Center, Atlanta, GA, 2UCSF Transplant Center, San Francisco, CA, 3Bristol-Myers Squibb, Princeton, NJ, 4Iowa Kidney Physicians, Des Moines, IA, 5Medical College of Wisconsin, Milwaukee, WI, 6Cedars-Sinai Medical Center, Los Angeles, CA, 7University of Cincinnati, Cincinnati, OH, 8Kaiser Permanente, San Francisco, CA, 9Maine Nephrology Associates, PA, Portland, ME, 10University Hospital Kidney and Liver Transplant Clinic, Dallas, TX

    *Purpose: BELA, a selective T-cell costimulation blocker, is approved for the prophylaxis of organ rejection in EBV-seropositive adult kidney transplant recipients. In phase 3 BENEFIT…
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