ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Reduction in UTI and UTI-Related Hospitalizations with Antibiotic Prophylaxis for Stent Removal in Kidney Transplant Recipients

    K. D. Belfield1, J. D. Smith2, L. F. Borges3, M. Malinis4

    1Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, 2Section of Nephrology, Yale School of Medicine, New Haven, CT, 3Western New England University College of Pharmacy, Springfield, MA, 4Section of Infectious Diseases, Yale School of Medicine, New Haven, CT

    *Purpose: After kidney transplantation ureteral stents are used while the anastomosis between the transplanted ureter and the bladder heals. While the use of stents reduces…
  • 2020 American Transplant Congress

    Depression Screening Protocol in Post Transplant Clinic. Implementing the A3 Scientific Method for Improving Patient Safety

    W. M. Potts, A. Anthony, K. Brayman, A. Doyle

    Charles Strickler Transplant Center, University of Virginia Health System, Charlottesville, VA

    *Purpose: Effect of the routine use of Patient Health Questionnaire PHQ-2 Screening in ambulatory transplant clinic to identify patients at risk for self-harm*Methods: Following a…
  • 2020 American Transplant Congress

    Early Prediction of Human Renal Allograft Rejection (AR) by Inflammatory Transitional B Cells

    A. Cherukuri1, A. Sharma1, R. Mehta1, H. Sundaram1, A. Salama2, D. Rothstein1

    1Starzl Transplantation Institute, UPMC, Pittsburgh, PA, 2UCL, London, United Kingdom

    *Purpose: Early prediction of AR within the 1st post-transplant year could identify at-risk patients for targeted therapeutic interventions to mitigate risk and improve outcomes.*Methods: In…
  • 2020 American Transplant Congress

    Hematopoietic Cell Kinase Promotes Kidney Fibrosis Through Autophagy Pathway

    C. Wei, L. Mou, K. Banu, M. Menon, W. Zhang, C. He, B. Murphy

    Icahn School of Medicine at Mount Sinai, New York, NY

    *Purpose: In our previous studies, we identified hematopoietic cell kinase (HCK) as a key driver of renal fibrosis through TGFβ/Smad3 pathway. Here in this study,…
  • 2020 American Transplant Congress

    Early Steroid Withdrawal in HIV+ Kidney Transplant Recipients is Associated with Increased Acute Rejection by 1 Year

    W. A. Werbel1, S. Bae2, S. Yu3, F. Al-Ammary4, C. M. Durand1, D. L. Segev3

    1Infectious Diseases, Johns Hopkins University, Baltimore, MD, 2Epidemiology, Johns Hopkins University, Baltimore, MD, 3Surgery, Johns Hopkins University, Baltimore, MD, 4Nephrology, Johns Hopkins University, Baltimore, MD

    *Purpose: Kidney transplantation among HIV+ recipients (HIV+ KT) is increasing, with excellent outcomes. Acute rejection (AR), however, is 2-3-fold more common than in HIV- KT.…
  • 2020 American Transplant Congress

    The Impact Of Weight Reduction Surgery And Morbid Obesity On Renal Function After Transplantation

    S. Negi1, N. Saberi1, P. Bouchard2, a. Andalib2, M. Cantarovich1, S. Paraskevas1, J. Tchervenkov1

    1RIMUHC, Montreal, QC, Canada, 2McGill University, Montreal, QC, Canada

    *Purpose: Morbid obesity is a significant barrier and renal transplantation is rarely offered to patients with Class III obesity (body mass index (BMI) > 40…
  • 2020 American Transplant Congress

    Altruistic Liver Donors at Thomas E Starzl Transplant Institute: Impact of the Educational Campaign: Gift of Life

    S. Ganesh, M. Molinari, L. Tubb, A. Tevar, C. Hughes, J. Behari, A. Humar

    Transplant Surgery, UPMC Thomas E Starzl Transplant Institute, Pittsburgh, PA

    *Purpose: Background and aims: There is an urgent need to expand access to living donor liver transplants due to a wide gap in the availability…
  • 2020 American Transplant Congress

    Evaluation of the Safety and Efficacy of Valganciclovir to Prevent Cytomegalovirus Infection in Pediatric Solid Organ Transplant Recipients Utilizing Two Dosing Regimens

    K. Le, A. Patel, N. M. Jasiak-Panek

    Pharmacy, Ann and Robert H. Lurie Children's Hospital, Chicago, IL

    *Purpose: Valganciclovir (VGCV) is FDA-approved for CMV prophylaxis in children aged one month to sixteen years old using the Pescovitz algorithm (7 x body surface…
  • 2020 American Transplant Congress

    Risk Aversion in Lung Transplantation: Organ Procurement Organizations Differ in Willingness to Pursue Non-Ideal Donor Organs

    S. E. Halpern1, A. McConnell2, S. Peskoe2, V. Raman3, O. K. Jawitz3, A. Y. Choi1, J. C. Haney3, J. A. Klapper3, M. G. Hartwig3

    1Duke University School of Medicine, Durham, NC, 2Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, 3Department of Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Lungs from non-ideal deceased donors are disproportionally discarded despite evidence that waitlisted candidates benefit from use of these organs. Organ procurement organizations (OPOs) individually…
  • 2020 American Transplant Congress

    Humanized Mouse Reveals the Cytoprotective Function of Hepatocyte RXFP1 in Liver Transplant Recipients

    H. Kojima1, S. Kageyama1, K. Kadono1, H. Hirao1, K. J. Dery1, T. Ito1, G. Sugahara2, Y. Ishida2, T. Saito2, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1Surgery, The Dumont-UCLA Transplantation Center, Los Angeles, CA, 2Division of Gastrointestinal and Liver Disease, Keck School of Medicine, USC, Los Angeles, CA

    *Purpose: RXFP1 (RLX family peptide receptor 1) is a cognate receptor for relaxin (RLX), an insulin-like growth factor, with vasoactive/remodeling properties. We have documented cytoprotective…
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