Am J Transplant, Volume 20, Suppl 3 Archives - Page 211 of 223 - ATC Abstracts

2020 American Transplant Congress
Changes in Health-Related Quality of Life During the First Year in Lung Transplantation Recipients
H. Zhou, J. Chen
Lung Transplant Center, Wuxi People’s Hospital, Wuxi, China
*Purpose: This longitudinal study was conducted to recognize the tracks of HRQOL during the first year after transplantation and the main factors associated with HRQOL…
2020 American Transplant Congress
Single Cell Profiling of PBMC Identifies Immune Populations Associated with High Risk of Early Acute Rejection
W. Zhang, S. Farouk, Z. Sun, W. Huang, Z. Yi, J. Fu, C. Wei, M. Fribourg-Casajuana, C. He, P. Cravedi, B. Murphy
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Our previous transcriptomic analysis of pre-transplant peripheral blood revealed a 23-gene set predictive of early acute rejection (EAR) post kidney transplant (JCI Insight, 2019).…
2020 American Transplant Congress
Stability of Immune Phenotype, Alloreactive, and Antiviral Immunity after Switch to Belatacept-Based Regimen after Kidney Transplantation
J. Schaenman, M. Rossetti, H. Wilhalme, V. Groysberg, G. Sunga, J. Gadzhyan, B. Abdalla, E. Lum, P. Pham, G. Danovitch, J. Veale, H. A. Gritsch, D. Elashoff, E. Reed, S. Bunnapradist
David Geffen School of Medicine at UCLA, Los Angeles, CA
*Purpose: This investigator-initiated study examines the impact of belatacept on T cell immune phenotype and function.*Methods: 19 patients with evidence of calcineurin inhibitor (CNI) toxicity…
2020 American Transplant Congress
Impact of Body Mass Index on Methodsof Assessing Glomerular Filtration Rate in Living Kidney Donors
Y. Lu¹, A. Naik¹, R. Doshi², K. Woodside³, M. Doshi¹
¹Internal Medicine, University of Michigan, Ann Arbor, MI, ²Internal Medicine, Vanderbilt University, Nashville, TN, ³Surgery, University of Michigan, Ann Arbor, MI
*Purpose: The current Organ Procurement and Transplantation Network (OPTN) policy on living kidney donors (LKD) require that all LKD candidates have measured glomerular filtration rate…
2020 American Transplant Congress
Simultaneous Liver and Kidney Transplant Outcomes after “Safety Net” Policy Change
D. Keys¹, T. Leventhal¹, S. Jackson¹, S. Riad¹, R. Spong¹, A. Matas¹, J. Rao²
¹University of Minnesota, Minneapolis, MN, ²Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Criteria for listing for Simultaneous Liver and Kidney (SLK) transplant changed on August 10, 2017. These changes were implemented to standardize the criteria for…
2020 American Transplant Congress
Reduction in UTI and UTI-Related Hospitalizations with Antibiotic Prophylaxis for Stent Removal in Kidney Transplant Recipients
K. D. Belfield¹, J. D. Smith², L. F. Borges³, M. Malinis⁴
¹Department of Pharmacy, Yale New Haven Hospital, New Haven, CT, ²Section of Nephrology, Yale School of Medicine, New Haven, CT, ³Western New England University College of Pharmacy, Springfield, MA, ⁴Section of Infectious Diseases, Yale School of Medicine, New Haven, CT
*Purpose: After kidney transplantation ureteral stents are used while the anastomosis between the transplanted ureter and the bladder heals. While the use of stents reduces…
2020 American Transplant Congress
Depression Screening Protocol in Post Transplant Clinic. Implementing the A3 Scientific Method for Improving Patient Safety
W. M. Potts, A. Anthony, K. Brayman, A. Doyle
Charles Strickler Transplant Center, University of Virginia Health System, Charlottesville, VA
*Purpose: Effect of the routine use of Patient Health Questionnaire PHQ-2 Screening in ambulatory transplant clinic to identify patients at risk for self-harm*Methods: Following a…
2020 American Transplant Congress
Early Prediction of Human Renal Allograft Rejection (AR) by Inflammatory Transitional B Cells
A. Cherukuri¹, A. Sharma¹, R. Mehta¹, H. Sundaram¹, A. Salama², D. Rothstein¹
¹Starzl Transplantation Institute, UPMC, Pittsburgh, PA, ²UCL, London, United Kingdom
*Purpose: Early prediction of AR within the 1st post-transplant year could identify at-risk patients for targeted therapeutic interventions to mitigate risk and improve outcomes.*Methods: In…
2020 American Transplant Congress
Hematopoietic Cell Kinase Promotes Kidney Fibrosis Through Autophagy Pathway
C. Wei, L. Mou, K. Banu, M. Menon, W. Zhang, C. He, B. Murphy
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: In our previous studies, we identified hematopoietic cell kinase (HCK) as a key driver of renal fibrosis through TGFβ/Smad3 pathway. Here in this study,…
2020 American Transplant Congress
Early Steroid Withdrawal in HIV+ Kidney Transplant Recipients is Associated with Increased Acute Rejection by 1 Year
W. A. Werbel¹, S. Bae², S. Yu³, F. Al-Ammary⁴, C. M. Durand¹, D. L. Segev³
¹Infectious Diseases, Johns Hopkins University, Baltimore, MD, ²Epidemiology, Johns Hopkins University, Baltimore, MD, ³Surgery, Johns Hopkins University, Baltimore, MD, ⁴Nephrology, Johns Hopkins University, Baltimore, MD
*Purpose: Kidney transplantation among HIV+ recipients (HIV+ KT) is increasing, with excellent outcomes. Acute rejection (AR), however, is 2-3-fold more common than in HIV- KT.…