Am J Transplant, Volume 20, Suppl 3 Archives - Page 211 of 223 - ATC Abstracts

2020 American Transplant Congress
TRANSBIO Study: Clinical Evaluation of Immunobiogram, a Novel In Vitro Diagnostic Immunoassay to Guide Adjustment of Immunosuppressive Therapy in Kidney Transplantation
J. Pascual¹, C. Jiménez², M. Krajewska³, C. Kotton⁴, D. Seron⁵, J. Portolés⁶, O. Witzke⁷, S. S. Sorensen⁸, A. Andrés⁹, T. Díez¹⁰, A. Ortega¹⁰, I. Portero¹⁰
¹Consorci Mar Parc de Salut, Barcelona, Spain, ²La Paz Hospital, Madrid, Spain, ³Wroclaw Medical University, Wroclaw, Poland, ⁴Massachusetts General Hospital, Boston, MA, ⁵Vall d’Hebron Hospital, Barcelona, Spain, ⁶Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, ⁷University Hospital Essen, University Duisburg-Essen, Essen, Germany, ⁸Rigshospitalet, Copenhagen, Denmark, ⁹12 de Octubre Hospital, Madrid, Spain, ¹⁰Biohope Scientific Solutions for Human Health SL, Madrid, Spain
*Purpose: Immunobiogram (IMBG) is a first-in-class blood-based pharmacodynamic immunoassay that provides the sensitivity/resistance profile of each patient’s lymphocytes to a panel of immunosuppressive drugs (IS).…
2020 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis (NASH) by Single-Nucleus RNA Sequencing
C. Kuscu¹, A. Mouhammed², C. Kuscu³, A. R. Wolen³, J. D. Eason³, D. Maluf³, V. Mas³
¹Dept of Surgery, Transplant Research Institute, James D. Eason Transplant Institute, University of Tennessee Health Science Center, Memphis, TN, ²Bioinformatics, University of Tennessee Health Science Center, Memphis, TN, ³Department of Surgery, University of Tennessee Health Science Center, Memphis, TN
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is a progressive disease and it constitutes a significant portion of the chronic liver diseases that affected more than…
2020 American Transplant Congress
Genetic Testing of Living Related Donors for Inherited Renal Disease Improves Evaluation and Promotes Informed Choice of At-Risk Living Donors
C. P. Thomas¹, M. E. Freese¹, D. A. Katz²
¹Internal Medicine, University of Iowa, Iowa City, IA, ²Surgery, University of Iowa, Iowa City, IA
*Purpose: Living kidney donors (LKDs) with a family history of kidney disease are at higher risk of end-stage renal disease (ESRD) compared to LKDs without…
2020 American Transplant Congress
Liver Transplantation for Patients with Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Survival Rates
I. A. Ziogas¹, K. P. Economopoulos², M. H. Hayat¹, L. K. Matsuoka¹, M. I. Montenovo¹, M. Izzy¹, S. P. Alexopoulos¹
¹Vanderbilt University Medical Center, Nashville, TN, ²Duke University Medical Center, Durham, NC
*Purpose: Liver transplant (LT) accompanied by neoadjuvant chemoradiation has emerged as the only curative option for unresectable cholangiocarcinoma (CCA). Although numerous centers have published their…
2020 American Transplant Congress
Living Donor Gender Disparities Vary by Donor-Recipient Familial Relationship
Y. Chen¹, Y. Hung², C. de Crescenzo¹, C. Rickert¹, Y. Hsu³, H. Yeh¹, D. Chang¹
¹Department of Surgery, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Sinai Hospital of Baltimore, Baltimore, MA, ³Department of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA
*Purpose: Women are more likely to be living transplant donors and less likely to be recipients. It has been difficult to distinguish how much of…
2020 American Transplant Congress
Transplant Regimen Adherence for Kidney Recipients by Engaging Information Technologies: Update on the Take It Trial
E. Yoon¹, S. Hurr¹, L. Curtis¹, D. Ladner², S. Nair³, M. S. Wolf¹
¹Center for Applied Health Research on Aging (CAHRA), Northwestern University Feinberg School of Medicine, Chicago, IL, ²Surgery, Northwestern Medicine, Chicago, IL, ³Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ
*Purpose: In 2017, the TAKE IT trial began its evaluation of a multifaceted, technology-enabled, transplant center-based intervention to monitor medication adherence behaviors among Kidney Transplant…
2020 American Transplant Congress
Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis
A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub
Indiana University School of Medicine, Indianapolis, IN
*Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
2020 American Transplant Congress
Immunomodulation with FasL Presenting Biomaterials Achieves Long-Term Survival of Allogeneic Islets in the Absence of Chronic Immunosuppression in a Non-Human Primate Model
J. Lei¹, H. Deng¹, T. Chen¹, K. Lee¹, C. Peters¹, Z. Yang¹, K. Deng¹, G. Rickert¹, I. Rosales¹, N. Serifis¹, M. Coronel², M. Hunckler², E. Yolcu³, H. Shirwan³, A. García², J. Markmann¹
¹Surgery, Mass General, Boston, MA, ²School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA, ³School of Mechanical Engineering, University of Louisville School of Medicine, Louisville, KY
*Purpose: The full potential of islet transplantation will only be realized by the development of tolerogenic strategies that obviate the need for maintenance immunosuppressants. We…
2020 American Transplant Congress
Outcomes Associated with Mycophenolate Weight-Based Dosing in Varying Immunologic Risk Kidney Transplant Recipients
A. A. Al-Bahou, A. R. Webb, M. Bloxam, L. J. Bowman Anger, R. S. Baliga, A. J. Brueckner
Tampa General Hospital, Tampa, FL
*Purpose: Mycophenolate acid (MPA) is traditionally dosed in kidney transplant recipients (KTR) using the FDA-approved fixed dosing which is irrespective of patient-specific variables such as…
2020 American Transplant Congress
CHAIR Score: A Novel Risk Stratification in Transplant Renal Artery Stenosis
X. Tian, W. Duan, T. Yan, X. Wu
Henan Province People's Hospital, Zhengzhou, Henan Province, China
*Purpose: The aim of the study is to evaluate the clinical application of CHAIR score based on creatinine (C), hypertension (H), age (A), imaging evidence…